Another paper showing improved QoL on combination therapy

[diogenes]

They are coming thick and fast now. Here is a paper showing markedly improved QoL of patients switched to combination therapy from T4 only:

Eur Thyroid Journal

Levothyroxine/Liothyronine

Combination Therapy and Quality of

Life: Is It All about Weight Loss?

Luba Freja Michaelsson

, Jeppe Lerche la Cour

, Bjarke Borregaard Medici

,

Torquil Watt

, Jens Faber

a, Birte Nygaard

,

Department of Endocrinology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark;

b

Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Published online: July 13, 2018

Department of Endocrinology, Herlev Hospital

University of Copenhagen, Herlev Ringvej 75

DK–2730 Herlev (Denmark)

E-Mail birte.nygaard @ regionh.dk

© 2018 European Thyroid Association

Published by S. Karger AG, Basel

E-Mail [e-mail]

karger.com

DOI: 10.1159/000490383

[megarub]

Could you supply a copy to TUK please?

[diogenes Remembering in reply to megarub]

Have done through Louise Roberts

[jimh111]

Thanks, will ask Louise for a copy. Unfortunately it doesn't appear to be a double blind study. The results seem striking good for such small doses of liothyronine.

[helvella Administrator]

Abstract available here:

karger.com/Article/Abstract...

[SilverAvocado]

Strange fixation on weight loss in this study. Is it supposed to imply that if added T3 ONLY allowed patients to lose the extra weight (although that's my words, the idea of it being extra weight isn't mentioned), then it wouldn't be a legitimate improvement?

Or maybe that T3 is purely a weightloss drug and the lost weight wouldn't be the excess that's put on due to being hypothyroid.