Hello I am on 2.5 grains NDT and quarter to half T3. I deliberately reduced from 3 grains because I seemed to rT3 crash (go very hypo suddenly). I have never tested positive for antibodies or inflammation. Does it matter if my T4 is lower end or should I try to up my NDT slightly. I have a mutated Dio2 so conversion is an issue.
Most people increase dose when they feel hypo, not reduce. The T3 in NDT and Liothyronine you are taking will overcome poor T4 to T3 conversion.
FT4 is almost always a lot lower on NDT than on Levothyroxine, sometimes below range. It doesn't matter that FT4 is low when FT3 is good and as your FT3 is in the upper range so you will be overmedicated if you increase dose.
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