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Thyroid UK
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Period gone missing

Hi, wonder if anyone has been similar.

I am 46 and until December my periods have returned to normal after been on 100 Levo. However, I have missed a period again, about 2 weeks late now, not pregnant!

My last blood test was in November and my TSH was 0.48 (.2 - 4.2). Unfortunately they didn’t test anything else.

I have made a doctors appointment, but can’t been seen for another 3 weeks. Don’t really know what to think. Don’t feel like it’s the menopause either.

Does anyone have any ideas?


2 Replies


TSH 0.48 indicates you are adequately dosed. I think it is more likely peri-menopause at age 46.


As you have Hashimoto's have you gone strictly gluten free yet?

Hashimoto's affects the gut and leads to low stomach acid and then low vitamin levels

Low vitamin levels affect Thyroid hormone working

Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten

According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)

But don't be surprised that GP or endo never mention gut, gluten or low vitamins. Hashimoto's is very poorly understood

Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies

Ask GP for coeliac blood test first

Persistent low vitamins with supplements suggests coeliac disease or gluten intolerance









Are your vitamins optimal?

For full evaluation you ideally need TSH, FT4, FT3, TT4, plus rechecking vitamin D, folate, ferritin and B12

Just TSH does not show if FT3 is adequate

DIO2 gene test too as a consideration


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