Antibody levels: Any idea what they mean please... - Thyroid UK

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Antibody levels

Leah11 profile image
5 Replies

Any idea what they mean please thankyou

SE Thyroid Peroxidase antibody 874 (<34)

SE Thyroglobulin antibody 255.6 (<115)

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Leah11
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SlowDragon profile image
SlowDragonAdministrator

Are you diagnosed as being hypothyroid and already on Levothyroxine?

Do you have other thyroid test results - TSH, FT4 and FT3

TPO antibodies are over 34

TG antibodies are over 115

So your antibodies are high this is Hashimoto's, (also known by medics here in UK more commonly as autoimmune thyroid disease).

About 90% of all hypothyroidism in Uk is due to Hashimoto's

Essential to test vitamin D, folate, ferritin and B12. Always get actual results and ranges. Post results when you have them, members can advise

Hashimoto's affects the gut and leads to low stomach acid and then low vitamin levels

Low vitamin levels affect Thyroid hormone working

Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten

According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)

But don't be surprised that GP or endo never mention gut, gluten or low vitamins. Hashimoto's is very poorly understood

Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies

Ask GP for coeliac blood test first

Persistent low vitamins with supplements suggests coeliac disease or gluten intolerance

gluten.org/resources/health...

thyroidpharmacist.com/artic...

thyroidpharmacist.com/artic...

amymyersmd.com/2017/02/3-im...

chriskresser.com/the-gluten...

scdlifestyle.com/2014/08/th...

drknews.com/changing-your-d...

thyroidpharmacist.com/artic...

Leah11 profile image
Leah11 in reply to SlowDragon

Diagnosed but not on levothyroxine thankyou

Leah11 profile image
Leah11 in reply to SlowDragon

TSH 103.5 (0.2 - 4.2)

FT4 9.3 (12 - 22)

FT3 2.2 (3.1 - 6.8)

Clutter profile image
Clutter in reply to Leah11

Leah11,

How are you diagnosed but not prescribed Levothyroxine? You are profoundly hypothyroid and need Levothyroxine. Make an appointment to see your GP as soon as possible.

Thyroid peroxidase and thyroglobulin antibodies are positive for autoimmune thyroid disease (Hashimoto's). There is no cure for Hashimoto's which causes 90% of hypothyroidism. Levothyroxine treatment is for the low thyroid levels it causes. Many people have found that 100% gluten-free diet is helpful in reducing Hashi flares, symptoms and eventually antibodies.

chriskresser.com/the-gluten...

thyroiduk.org.uk/tuk/about_...

For maximum absorption Levothyroxine should be taken with water 1 hour before, or 2 hours after, food and drink, 2 hours away from other medication and supplements, and 4 hours away from calcium, iron, vitamin D supplements, magnesium and oestrogen.

It takes 7-10 days for Levothyroxine to be absorbed before it starts working and it will take up to six weeks to feel the full impact of the dose. Symptoms may lag behind good biochemistry by several months.

You should have a follow up thyroid test 6-8 weeks after starting Levothyroxine. Arrange an early morning and fasting (water only) blood draw when TSH is highest, and take Levothyroxine after your blood draw.

thyroiduk.org.uk/tuk/about_...

SlowDragon profile image
SlowDragonAdministrator in reply to Leah11

Your GP should have contacted you immediately on getting these results

Make an urgent appointment today or tomorrow. You are extremely hypothyroid

Your GP should start your immediately on 50mcg of Levothyroxine (possibly higher dose, definitely not a lower dose)

Ask for coeliac testing and vitamins tested

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