medichecks results

[Bola77]

just got results back from the ultra check the one thing i dont quite understand is the peroxidase antibodies my result 89 (0.00-34.00)

my question is what are they and what can i do about it?

thanks

[Clutter]

Bola77,

Thyroid peroxidase antibodies are positive for autoimmune thyroid disease (Hashimoto's). There is no cure for Hashimoto's which causes 90% of hypothyroidism. Levothyroxine treatment is for the low thyroid levels it causes. Many people have found that 100% gluten-free diet is helpful in reducing Hashi flares, symptoms and eventually antibodies.

chriskresser.com/the-gluten...

thyroiduk.org.uk/tuk/about_...

[Bola77 in reply to Clutter]

thank you no one has told me i have hashis but through a bit of research i did wonder ill check the links thanks

[Clutter in reply to Bola77]

Bola77,

UK doctors can be a bit peculiar about the term "Hashimoto's" and are more likely to say it is "chronic thyroiditis", "autoimmune thyroiditis" or just "thyroiditis".

[Bola77 in reply to Clutter]

or in my case "your symptoms have nothing to do with thyroid but ill up your dose anyway"

[Clutter in reply to Bola77]

Bola77,

What were your thyroid results and ranges?

GPs don't usually raise dose unless you are undermedicated and being undermedicated makes one symptomatic. Doctors often don't accept that Hashimoto's also causes symptoms. My doctors told me my symptoms were non-thyroidal because I had euthyroid Hashimoto's.

[Bola77 in reply to Clutter]

tsh 4.99 (0.27-4.20)

free thyroxine 15.7 (12.00-22.00)

free t3 5.41(3.10-6.80)

t4 107 (59.00-154.00)

reverse t3 21 (10-24)

reverse t3 ratio 16.77 (15.01-75.00)

thyroglobulin antibody 13.600 (0.00-115.00)

[Clutter in reply to Bola77]

Bola77,

Good job your GP increased dose because you were very undermedicated to have TSH 4.99 while taking Levothyroxine.

The goal of Levothyroxine is to restore the patient to euthyroid status. For most patients that will be when TSH is 0.3 - 1.0 with FT4 in the upper range. FT4 needs to be in the upper range in order that sufficient T3 is converted. Read Treatment Options in thyroiduk.org.uk/tuk/about_...

You should have a follow up TFT 6-8 weeks after increasing dose in case further adjustment is required. Arrange an early morning and fasting (water only) blood draw when TSH is highest, and take Levothyroxine after your blood draw.

[Bola77 in reply to Clutter]

thats my result yesterday two weeks after my doctor upd my dose!

[Clutter in reply to Bola77]

Bola77,

Well make sure your GP retests 6-8 weeks after the dose increase as you may need another dose increase.

[SlowDragon Administrator]

Your antibodies are high this is Hashimoto's, (also known by medics here in UK more commonly as autoimmune thyroid disease).

About 90% of all hypothyroidism in Uk is due to Hashimoto's

Essential to test vitamin D, folate, ferritin and B12.

Always get actual results and ranges. Post results when you have them, members can advise

Hashimoto's affects the gut and leads to low vitamin levels

Low vitamin levels stop Thyroid hormone working

Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten

According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)

But don't be surprised that GP or endo never mention gut, gluten or low vitamins. Hashimoto's is very poorly understood

Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies

thyroidpharmacist.com/artic...

thyroidpharmacist.com/artic...

amymyersmd.com/2017/02/3-im...

chriskresser.com/the-gluten...

scdlifestyle.com/2014/08/th...

drknews.com/changing-your-d...

All thyroid tests should be done as early as possible in morning and fasting and don't take Levo in the 24 hours prior to test, delay and take straight after. This gives highest TSH, lowest FT4 and most consistent results

Link about antibodies

thyroiduk.org.uk/tuk/about_...

Link about thyroid blood tests

thyroiduk.org/tuk/testing/t...

list of symptoms off, tick all that apply

thyroiduk.org/tuk/about_the...

See Box 1 towards end of article

Some possible causes of persistent symptoms in euthyroid patients on L-T4

onlinelibrary.wiley.com/doi...

[Bola77 in reply to SlowDragon]

thanks ill read yes the results are early fasting blood test levo taken after

ferritin 51.6 (13.00-150.00)

crp 0.1 (0.00-5.00)

vit D 58.5 (50.00-200.00)

folate 7.57 (2.91-50.00)

active b12 81.9 (25.10-165.00)

[SeasideSusie Remembering in reply to Bola77]

Bola77

Although none of your levels are dire, they are on the low side.

ferritin 51.6 (13.00-150.00) - For thyroid hormone to work (that's our own as well as replacement hormone) ferritin needs to be at least 70, preferably half way through range. You can help raise your level by eating liver regularly, maximum 200g per week due to it's high Vit A content, and including lots of iron rich foods in your diet apjcn.nhri.org.tw/server/in...

vit D 58.5 (50.00-200.00) - The Vit D Council recommends a level of 100-150nmol/L. If you don't already supplement then my suggestion would be to take 5000iu daily for 3 months then retest. A good supplement - bodykind.com/product/2463-b... When you've reached the recommended level then you'll need a maintenance dose which may be 2000iu daily, it's trial and error so it's recommended to retest once or twice a year to keep within the recommended range. You can do this with a private fingerprick blood spot test with City Assays vitamindtest.org.uk/

There are important cofactors needed when taking D3

vitamindcouncil.org/about-v...

D3 aids absorption of calcium from food and K2-MK7 directs the calcium to bones and teeth where it is needed and away from arteries and soft tissues where it can be deposited and cause problems.

D3 and K2 are fat soluble so should be taken with the fattiest meal of the day, D3 four hours away from thyroid meds.

Magnesium helps D3 to work and comes in different forms, check to see which would suit you best and as it's calming it's best taken in the evening, four hours away from thyroid meds

naturalnews.com/046401_magn...

Check out the other cofactors too.

folate 7.57 (2.91-50.00)

active b12 81.9 (25.10-165.00)

Your folate level should be at least half way through it's range so I would suggest taking a good B Complex with 400mcg methylfolate, eg Thorne Basic B, which also contains 400mcg methylcobalamin which might give your B12 a bit of a boost as that's less than half way through it's range.

[Bola77 in reply to SeasideSusie]

thank you so much for taking the time to reply to me