Thyroid UK
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NDT struggles

Hi all, so as I’ve posted about already I’m struggling to get my optimal level on NDT. I’m now on a grain and a half and will go up to two in a weeks time. (I was on 75mg Levo for ten months and have been on NDT for two and a half weeks)

My concern is my mental problems have been worse this past week. I didn’t think it was possible for them to be worse. I’m terribly anxious, verging on confused, scared, brain fogged to the point of feeling like I’m not here and could pass out, and have an overwhelming feeling like I could lose my mind.

Will this pass? Is this a transition thing? I see my specialist on Thursday. Need some reassurance badly :(

4 Replies


Has the anxiety etc. got worse since you switched to NDT from Levothyroxine?


Initially it was better and now it’s worse. Everything else seems improved apart from mental issues


Hi clutter, initially it was better now it’s worse



I suggest you have a thyroid function test including FT3 before increasing further to see where FT3 is. 1.5 grains is equivalent to 97.5mcg Levothyroxine so you may be overmedicated and that will exacerbate anxiety.

If you are not overmedicated it may be worth trying a different brand of NDT as some people have to try a few different brands before they find one which suits.


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