Julie1166 What on earth is her GP doing leaving her on 150mcg Levo with results like that! The aim of a treated hypo patient generally is for TSH to be 1 or below or wherever it is needed for FT4 and FT3 to be in the upper part of their respective reference ranges. She needs to make an appointment with her GP and ask for an increase of 25mcg, followed by regular retesting/increases of 25mcg every 6-8 weeks until she feels well.
To support her request, she should take the following information from ThyroidUK's main website thyroiduk.org.uk/tuk/about_... > Treatment Options:
"Dr Toft states in Pulse Magazine, "The appropriate dose of levothyroxine is that which restores euthyroidism and serum TSH to the lower part of the reference range - 0.2-0.5mU/l.
In this case, free thyroxine is likely to be in the upper part of its reference range or even slightly elevated – 18-22pmol/l. Most patients will feel well in that circumstance.
But some need a higher dose of levothyroxine to suppress serum TSH and then the serum-free T4 concentration will be elevated at around 24-28pmol/l.
This 'exogenous subclinical hyperthyroidism' is not dangerous as long as serum T3 is unequivocally normal – that is, serum total around T3 1.7nmol/l (reference range 1.0-2.2nmol/l)."
She can obtain a copy of the article by emailing email@example.com print if off and highlight question 6 to show her GP.
Dr Toft is past president of the British Thyroid Association and leading endocrinologist. He also wrote a booklet for patients, published by the British Medical Association, "Understanding Thyroid Disorders", which says "many people do not feel well unless their levels are at the bottom of the TSH range or below and at the top of the FT4 range or a little above." The booklet is available from pharmacies and Amazon for £4.95
Also, her high antibodies confirm autoimmune thyroid disease aka Hashimoto's which is where antibodies attack the thyroid and gradually destroy it. The antibody attacks cause fluctuations in symptoms and test results. She can help reduce the antibodies by adopting a strict gluten free diet which has helped many members here. Gluten contains gliadin which is a protein thought to trigger antibody attacks. Supplementing with selenium L-selenomethionine 200mcg daily and keeping TSH suppressed can also help reduce antibodies.
Doctors tend to dismiss antibodies as being of no importance and don't understand the nature of Hashi's so she's best learning as much as possible about it so she can help herself.
Hashi's and gut/absorption problems tend to go hand in hand and often low nutrient levels are the result. If she's had the following tested, post the results, say if she is supplementing, with what and the dose. If not already tested she should ask for them to be done:
Full blood count