Thyroid UK
85,754 members100,686 posts

Block replace

Hi I ended my block and replace treatment on June 30th . Treated with 20mg carbimazole and 120 thyroxine for Graves' disease, hoping for it to go into remission.

Had bloods back , has come back abnormal. Tsh only level so far I have 0.02. Is it normal for results to drop and then go back up when thyroid kicks in on its own?

Any help please do not want to think remission has failed!

12 Replies
oldestnewest

Angelstar444,

What was your TSH when you were on B&R?

TSH 0.02 is suppressed and I would have expected the lab to check FT4 and FT3 as you were recently hyperthyroid.

Reply

Everything was in range when in treatment. Plan was to stop all meds and hope Graves go into remission.

I don't have all the levels GP hasn't phoned. I'm hoping that levels drop and then rise and this is normal!! 🤞

Reply

Angelstar444,

No, sorry, as TSH has dropped remission isn't working.

Reply

Thank you.

I can't believe it's happened so fast I stopped meds less than 2 weeks ago :-(

My thyroid hasn't even had a chance to get going!

Reply

Angelstar444,

Do you have Graves antibodies?

Reply

Yes I did when first diagnosed 16mths ago.

I don't think I have been tested since so I don't know now

Reply

Angelstar444,

Permanent remission fails in more than 50% of Graves patients. However, your remission hasn't really started at all.

Reply

I know! That's what I feel.

Do you think I needed longer on block and replace?

Reply

Angelstar444,

12-18 months is usually long enough. I think you'll have to go back on B&R if FT4 and FT3 are rising too.

Reply

It's just so upsetting and frustrating! Pinned all my hopes on it working as was waiting to start trying for a baby

Reply

Angelstar444,

Being hyperthyroid doesn't stop you conceiving but you will need to switch to Propythiouracil (PTU) when you become pregnant as Carbimazole can cross the placenta.

Reply

Or you could try just Carbimazole. B&R didn't work for me but titrating Carb did.

Reply

You may also like...