Transition NDT to T3

[AKatieD]

Hi All

I have started taking my first lot of Tiromel. I started with 1x 25mcg during the morning and result was feeling very weary. I tried taking it at night and could not sleep so went back to day time. I thought perhaps drop my NDT more or take more tiromel.

Whatever I do just seems to make me feel tireder, which was never one of my hypo symptoms. Any ideas what is going wrong or should I just go back to NDT only?

Thanks

[Jazzw]

OK, I've had a quick look at your posts from 2 months ago.

So how much NDT are you taking now? Have you stopped your levo altogether?

How long have you been taking the T3?

I think we need a bit more info to advise...

[AKatieD in reply to Jazzw]

Ok sorry thought I was asking general question.

Yes stopped all levo. Been taking 6 grains ndt only. Started by adding the t3 2 weeks ago but not sure if worth persisting as immediate effect tiredness?

Appreciate 2 weeks not long.

Also before I started ft4 and ft3 back in range. Ft3 about 70% through range.

Thanks

[shaws in reply to AKatieD]

6 grains of NDT is equal to 600mcg of levothyroxine so I think you've overshot well above what would make you feel better. Many make the mistake of thinking 60mg is 60mcg but it isn't.

I'd suggest stopping dose for a few days to let your system recover.

Always start on a dose equal to what your previous dose was, i.e. 50mcg if equal to around half tablet of T3 or half grain of NDT.

[AKatieD in reply to shaws]

Thanks but 6 grains is what gave me the mid range blood test results as per the answers to Clutter and Jazzw so don't think i am over replaced. I was ok on that but not feeling as well as I have been before so was going to transition to T3 to see if that made me feel better (as per suggestion from Greygoose).

But as I am feeling like I have been hit by sledge hammer on lowest dose T3 (1 pill of 25 mcg) not sure it is worth persisting with transition and this is what my question was about? Is that normal at the start and should i persist or does it mean t3 doesnt agree with me?

[Clutter]

AKatieD,

Have you had a thyroid test since you've been taking 6 grains? Your FT3 was 5.65 on 150mcg Levothyroxine + 3 grains NDT so I think FT3 could be over range on 6 grains. Adding 25mcg T3 is equivalent to adding another grain of NDT. Overmedication causes fatigue.

[AKatieD in reply to Clutter]

Yes thanks Clutter.

On 6 grains in June results were

FT4 96 (59 - 154)

FT3 5.59 (3.1 - 6.8)

Have had much higher levels and never fely tired like this before, to the extent of falling asleep during day

[Clutter in reply to AKatieD]

AKatieD,

How long had you been on 6 grains when you tested?

FT3 5.59 is good why are you trying to push it up? 25mcg T3 will almost certainly push your FT3 over range.

[AKatieD]

Hi again. Because have not felt well since reducing meds over last 9 months so trying to find somewhere I can live with and was hoping t3 was going to help that. Felt well when meds were over range and was hoping t3 would help feel well within range.

Over a month on 6 grains before testing.