I suffer from myxeodema, have done for a long time, and it has been well controlled on 150ug Levothyroxine. It was due to undiagnosed autoimmune thyroid disease. Recently I've been trying to manage pain for other conditions and was given Tramadol (which was horrendous and only lasted 2 weeks) but since then I have suffered neck pain and now I've been told my thyroid levels are way out. A locum gp has cut my medication from 150ug to 100ug. Has anyone else had problems combining these two drugs? Would love some feedback before I jump in all guns blazing. Wondering if it's another incompetent prescribing mistake. GP had wanted to give me some other tablets and start autoimmunity tests when I told her I had myxoedema, obviously she hadn't even read my notes. Thanks.