Odd anxiety, lightheadedness

Since being diagnosed hypothyroid 3 mths ago my Tsh has reduced from 36 to 13 in 50mcg but every time I try to increase the dose to 75mcg I feel so odd, sped up, freq passing urine, loose toilet and generally to fast without energy. When I get cold I take hours to warm up. I do not really feel any better on medication but am scared to stop in case I feel worse. The anxiety feels very real but very unnatural like an odd release internally that you feel come and go?? Adrenaline or something ? I'm clueless

6 Replies

  • richard123, Some people find they need to increase very slowly. Instead of taking 75mcg every day, you could try taking 50mcg one day and 75mcg the next for a while and see how that feels.

  • richard,

    Many years of low thyroid hormone can compromise the adrenal glands and there is thought that to raise the metabolism (through thyroid hormone replacement) and not address possible adrenal hormone imbalances, will create further.

    GP's will serum blood test cortisol levels but this will only give a total amount (indicating if they are working well) but not the "free" amount of cortisol which is active. A saliva test will measure the available "active" cortisol (& DHEA) secreted at set times over a 24 hours period. The results will allow you to see any imbalances in the daily circadian pattern so enabling use of correcting supplements to aid your adrenal health. Unfortunately this test is not generally used or recognised by GP's.

    "They" tried to take me down the POTS road ..... but there are many weird syndromes whose symptoms overlap with many weird autoimmune conditions, etc, and as there is no cure for POTS, I figured it better to concentrate on my thyroid (& associated) issues.... it paid off.


    Saliva Stress Test (test ref END01)


    The cost is £77.00 which is a discounted price for THyroidUK when code A42AQ is used.


  • Thank you for your reply, very helpful I will arrange the saliva stress test.

  • I was like this for years: not being euthyroid, but increasing T4 would cause anxiety and other undesirable symptoms. My adrenal glands were not functioning well and I had multiple nutritional deficiencies (from gluten enteropathy). I had several saliva cortisol tests that showed bad rhythm and high cortisol at night. I supplemented with hydrocortisone (<20mg daily, per Jefferies) for a while, went on T3-only for a while to circumvent the T4->T3 conversion problem, and was on a comprehensive nutritional supplement program for a long time. The problems finally resolved.

    StopTheThyroidMadness.com does talk about how the adrenals need T3, but when you can't convert T4 well, you are in sort of a Catch-22. You could try adding some T3 to your 50mcg T4, and see if that improves the situation. Supplementing with vitamin C, adaptogens, etc. to help the adrenals, might not help much if you have insufficient T3 and other nutritional deficiencies.

  • Thank you, when I next have blood tests I will ask GP to refer to endo as GP says great numbers coming down but I can't manage to get over 50-75 on alternative days without feeling so sped up its awful. Somehow I find tired easier than fast yet before all this I was generally hyperactive all my life.

    I am taking omega 3, good multi vit, vit D spray will add vit c daily for sure and ask GP to refer

    Thank you

  • If you can, find out if the endo you were referred to specializes in thyroid. So many of them these days are preoccupied treating diabetes patients, that they don't have a handle on thyroid patients with special issues, like getting anxiety from T4 treatment.

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