Calcitonin

[Summer64]

I've recently read a bit about this and it is produced in humans in the thyroid gland. As mine has been destroyed by RAI does this mean it is replaced in the levothyroxine we take or are we left without any?

[Clutter]

Summer64,

I don't believe we get any calcitonin from Levothyroxine or Liothyronine. It is said that there is calcitonin in Natural Dessicated Thyroid (NDT) but it doesn't appear to be measurable in it.

What is the role of calcitonin in the body?

However, the importance of this role in humans is unclear, as patients who have very low or very high levels of calcitonin show no adverse effects. Calcitonin reduces calcium levels in the blood by two main mechanisms: It inhibits the activity of osteoclasts, which are the cells responsible for breaking down bone.

yourhormones.info/hormones/...

Salmon Calcitonin was produced but discontinued when it was found to be carcinogenic.

[radd]

Summer,

Calcitonin modifies increases in serum calcium and increases 1,25D production and a deficiency has been found in people with Hashimotos and so presumably RAI. However I read of extrathyroidal sites of calcitonin production.

Levothyroxin is said to only contain thyroxin hormone and not calcitonin but NDT is said to contain T4, T3 ,T2, T1 and calcitonin.

In a healthy person calcitonin acts directly on bone to inhibit resorption by reducing the activity of osteoclasts. I do not know the implications of a calcitonin deficiency and suspect it would vary from person to person depending on other health issues.

.

bmj.com/content/285/6347/1010

[Summer64 in reply to radd]

They never test for it do they. I have osteomalcia and osteoporosis so wonder if there is a connection there somewhere. Up until 1980's people were given NDT weren't they so I wonder if their bone health was better or not.

[radd in reply to Summer64]

There appears to be very little studies after the salmon calcitonin.

If you are worried have you considered medicating NDT ? ?

[Summer64 in reply to radd]

I've never asked about that. I wouldn't dare try without being under a doctor for it.

[stockman27]

No T4 does not replace anything other than T4. I went to a seminar organised by the British Thyroid assoc. The drs there said that there is no need foir Calicton. Hmm and I wear a ginger wig and a red nose. If we were not supposed to have calciton then our bodies would not have evoled that way. Armour and other NDP has all the ingredients ie T1, t2, t3 and T3 and of course Caliton and there is other ingenients referred to as agen x. Our endo are a failed science.

John c

[helvella Administrator Thyroid UK in reply to stockman27]

One of the problems is that there seems to be absolutely no evidence that calcitonin from a pig's thyroid can be delivered into a human from desiccated porcine thyroid. Even if delivered, do we know whether porcine calcitonin has the same (or any) effect in humans? Good or bad.