Last October my dr upped my Synthroid from 25 mcg to 50 mcg...the result a nosedive into hyper symptoms which made me feel like I was going crazy. Anxiety, pins/needles in feet and hands, feeling of doom, joint pain, muscle tension, crying nonstop. I woke up on Nov 15th in someone else's body. Returning to 25mcg has resolved all the symptoms except the joint pain. I started Erfa thyroid in April.