Thought I would post an update.
I started taking T3 3 1/2 weeks ago. I started on 150mcg T4 and introduced 25mcg T3. Wow, bit of a mistake. I got heart palpitations and shakes for around 3 hours. Not nice. I then started taking 150mcg T4 and 12.5mcg T3. I started noticing relief of muscle and joint pains straight away.
Anyway I gradually reduced T4 and increased T3. I am currently taking no T4, just T3. My T3 dose is split into 3 per day. 75mcg at 8am, 37.5 mcg at 3pm and 37.5 at 11pm. I am going to increase my afternoon and evening dose to 50mcg today.
My temperature is now normal, my resting heart rate went from 50 to 70, my muscle/joint pains are 95% better, my bowel movements are every other day instead of once every 1 to 2 weeks, my physical fatigue is 50% better. My brain fog and falling asleep has not improved as of yet.
I also have low testosterone (normal range for NHS), equivalent to the average for an 85 to 100 year old. I think this is why the mental fog and falling asleep has not improved. I will be trialing Testosterone replacement therapy in a couple of weeks to see if it helps.
So there is light at the end of the tunnel with T3 only in my case. I hope to find the ideal dose sometime in the next 4 to 6 weeks.
I will caution you all to not increase the dose as rapidly as i have. I have overdosed twice on T3 and pushed my blood pressure up to 130/99 and resting heart rate to 90 on several occasions. I have also felt really crappy on several occasions and just going for a 15 minute walk 3 days ago pushed my heart rate up to 105. T3 is no joke. It usually takes 3 or 4 days for blood pressure and heart rate to settle down after an increase of dosage.
I am feeling pretty good now with a blood pressure of 121/74 and a resting heart rate of 71 this morning. After increasing my afternoon and evening dose I am going to give it at least 2 weeks between changes in the future.