Good News

There are some bright spots in the thyroid research world. Diogenes and his collaborators being one we are familiar with and Dr. Bianco and his team another. Another one most are probably not familiar with is Dr. Anthony Hollenberg who has spend years investigating the CoActivators and CoRepressors. This is a very short clip on his current investigations which hold promise for better diagnostic tests. PR

"According to Hollenberg, researchers hypothesize that cellular thyroid hormone signaling is different from the level of thyroid hormone in a person’s circulation. Current animal model test results are being used to spur new diagnostic testing in humans. He said the goal is for better diagnostic testing for people with thyroid disease as well as better approaches for treating metabolic disease."

healio.com/endocrinology/th...

6 Replies

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  • Thanks for some more encouraging research. Let's hope that things can be turned head over heels. Wouldn't that be wonderful.

  • Seems I entirely missed Endo 2015! Link to overview of papers delivered:

    healio.com/endocrinology/cb...

    Maybe there are others that are as interesting as Hollenberg's sounds? Funny how so much of this seems to stay firmly in the realms of academic interest and so little travels out to the real world, real patients.

    Thanks, PR.

  • Rod, I would like to see the whole presentation but doubt it is reasonably priced. The tidbit he gives us sounds promising but I'm eager for more details of where he is headed. I've long been curious about how the control systems for the various parts are coordinated to achieve the overall goal. Diogenes and his group are the first inkling of a coordinated approach that surely must exist. Thanks for posting the link, I forgot to do that. PR

  • The sad part is that all this is nothing new. Before the TSH, they treated by symptom relief, not labs and no one has listened. Now they start all over again, perhaps getting the info from old text books..it's all there. You don't need some Damn test to tell when a patient is improving or still ill.

  • faith63, I hate to burst your bubble but thyroid patients face now, and have always faced, the same two universal hurdles. First is a timely and accurate diagnosis, and second is adequate treatment. Even in the days before the first attempt at a laboratory standard, the BMR in the 1930s, patients were not guaranteed success. When my Mother was diagnosed in 1927 she was placed on 1/4 grain, and left at that dose for the next 55 years, she paid a terrible price. My Father, who had obvious problems on the thyroid/adrenal axis, was never diagnosed in his entire life even though he had 3 heart attacks in the 1960s. A timely and accurate diagnosis and adequate treatment have never been guaranteed. It has always been just the luck of the draw, not an intelligent uniform standard. PR

  • I didn't know. I am sorry about your Parents. I think getting help may be better now, at least here in the US...We have Pituitary Centers and maybe more resources.

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