Hi, I'm writing a letter for my GP as she needs to write to an endo for me and I want to explain the catch 22 situation that can arise with low thyroxine take up and low cortisol. I understand the idea that as every organ needs T3 to function adrenals will slow down if not enough T3 in cells, plus the stress of this long term to the body also raises the demand on adrenals however, could anyone explain to me how low cortisol in it's turn prevents efficient thyroid take up? By what mechanism does this happen? Thanks you
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