Could it be she has Hashimoto's, which often has a period of hyperactivity followed by underactivity b/c of the damage done to the thyroid gland? It goes hand in hand with coeliac because they're both autoimmune illnesses (so is lupus) and likely caused by the same root, which is often (always, in the case of coeliac) caused by food intolerances (gluten, in the case of coeliac). Wheat and dairy sensitivity are apparently a very common cause of Hashimoto's, according to my endocrinologist. You can treat the thyroid symptoms with thyroxine (etc) and the vitamin deficiencies with supplements, but you won't eliminate the root cause until/unless you address any food sensitivities. Good luck to your daughter! I was diagnosed hypo 11+ yrs ago but was fairly stable until after I had my daughter 5 yrs ago, then all the real trouble began (debilitating energy crisis, etc, followed by 4 miscarriages close together). I feel her pain! On the positive side, I found an excellent functional medicine practitioner & endocrinologist working together, who put me on an elimination diet to identify food intolerances. It took some weeks, but suddenly one day my energy came back (a few months later I'm also 13+ wks pregnant -- all my miscarriages were pre-seven weeks -- with good chances of having this one stick around, now that my gut is healed). It's worth giving the gut issues consideration.