My GP wrote to my endo regarding my lack of response to 75mg Thyroxine. To my surprise, endo was willing to advise 10 mg of T3 per day. I understand that this dose needs to be split into 5mg. How do people take it, morning and evening and do you need to take it on empty stomach like thyroxine? The pharmacy said it takes 5 days to order by special delivery. I knew it was expensive but it sounds that it is not readily available. I am putting high hopes into T3 and learnt a lot from this forum, so thanks everyone. I am hoping to have more energy and lose a few pounds. My T3 is 4.3, range is 3.9 to 6.7. This dose is quite small but a good start. Do people always start with 10mg?