Thyroid UK
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Hi all was trying 100mcg thyroxine with 20mcg t3 wondering whether to go back to 75mcg throxine with 20mcg t3? Seeing Endo tomorrow

Hi all am seeing Endo tomorrow in cornwall. I have been on 20 mcg t3 and 75mcg thyroxine for just over a year but was exhausted so gp agreed to increase to 100 mcg throxine. Think i feel a bit better no great difference. Still feeling very anxious first thing and hot yet cold extremities but could be over worrying things. Bloods results on 75mcg thyroxine Oct TSH 0.63 ft4 16.1 Dec TSH .37 ft4 13.3 ft3 5.1 Bloods after increase thyroxine to 100mcg June after 2months with same 20mcg t3 TSH 0.56 ft4 12.3 ft3 5.1 Endo won't increase t3 siting danger to heart bones. I also take hrt patch as oestroidol level neglible. Great news on thyroid uk news website about supplies of t3 becoming available. When I used to be on thyroxine alone my t4 used to be much higer until I started having problems after years on it and TSH went to 11. Thanks peeps

2 Replies

You may wish to read these in relation to heart and bone density.

Also this:

Some women are told to be wary of taking thyroid medication because it can leach the calcium from bones. This assumption is now outdated. The research on people taking extremely high doses of thyroid hormone is mixed, but it is now known that thyroid pills in appropriate doses are good for your bones. Moreover, it has recently become apparent that the fairly common situation of undetected and untreated low thyroid is the cause of bone calcium depletion. Dr. Richard and Sharilee Shames


In the 1970’s and 1980’s, many faulty studies were published that led to the erroneous conclusion that TSH-suppressive dosages of thyroid hormone decrease bone mineral density in most patients. Some conventional endocrinologists wrongly extrapolated from these studies that TSH-suppressive dosages lead to osteoporosis and increased risk of bone fracture. Among our patients who have used TSH-suppressive dosages of T3-containing preparations from 1-10 years, bone densitometry has shown that their density is HIGHER than other men and women for the same age.

The finding of higher bone density among patients taking higher-end dosages of thyroid hormone suggests that under-treatment with thyroid hormone can contribute to lower bone density. The lower bone density is likely to result from patients being unable to engage in weight bearing exercise due to low motor drive and decreased metabolic capacity. Hypothyroid patients using T4 replacement dosages commonly lack the drive to engage in weight bearing exercise, indicating that replacement dosages are often tantamount to gross under-treatment. Dr. John Lowe, Boulder Colorado (119)


Optimising the serum dialysis free T4 and T3 levels in all my patients has not contributed to osteoporosis at all (on the contrary, serial DECCA scans have usually shown dramatic increases in bone density despite my never prescribing any drugs for osteoporosis but using nutritional and metabolic corrective approaches instead); and cardiac arrhythmias are taken care of by making sure there is no functional deficiency of the pertinent minerals in the appropriate fluid spaces (RBC/packed cell levels in the case of magnesium and potassium). Not doing these things, and assuming that a “normal” TSH always means normal – even optimal – thyroid hormone function, is causing vast under-diagnosis and under-treatment in millions of patients in the US and around the world. Surveys of patient satisfaction with treatment, and websites devoted to this topic, invariably show deep distrust of the adequacy of their treatment, Dr John Dommisse, Tucson, Arizona


As regards T3 in particular the heart requires adequate T3 for it to function normally. If it does not have enough arrhythmia may result.

Hope this helps. Jane x x


Thank you Jane for the information Heidi x


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