Has anyone used procalopride laxative. I have slow gut motility and cant go to the toilet at all without a laxative. Dulcolax usually works but I feel so nauseous and shivering on it. I have to use a stimulant laxative as nothing else helps.
I have been prescribed procalopride which is a big step to take I am told. Any feedback would be helpful I feel so poorly with it all. I eat and drink all the right things to no avail. I have been offered irrigation or a stoma but never had any bowel motility tests just colonoscopy. I have upper gastric motility issues. Thank you.
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I don’t understand why they haven’t done any motility tests or gastric emptying studies……have you asked for them? I tried that medication and it didn’t work for me it messed with the nerves in my bowel and made it harder for me to go. I hope it helps you good luck xx
Thank you. I have had reams of upper gastric tests, stomach gastric emptying, endoscopy, ph acid levels, sclederma screening, bile acid, failed peristalsis, ct scans hiatus hernia found sll with my gastroenterologist.
Colonoscopy but no bowel motility tests. Attended bio feedback but that did nothing. I am awaiting a referral app to see london bowel people.
My gastro had said he didnt want to prescribe med like procalopride as it messes with nerves but has relented. I am loath to risk anything that can make matters worse. Today is an awful day due to dulcolax. Its working but I feel dreadful, shaking, cold, nauseous the full works.
Sorry procalopride didnt work for you. All my issues started after having my gall bladder removed. Hope you find a manageable solution ongoing. Best wishes.
That’s the same as me I had my gallbladder out in 2010!! Nope the drugs did nothing for me the only thing that helped was milk of magnesia but I couldn’t take it longterm as it also caused nerve issues I now have an ileostomy which has solved the problems but I have a lot of other health issues that lead me too this but it was well worth it I love my stoma and couldn’t do life without it xx
Bless you. That was a big step. Pleased its worked out ok for you though. Our organs interplay so much, loosing the gall bladder is a big thing not to be undertaken lightly. Sorry you have other health issues too. Thanks for letting me know re the nerve issues too, very useful info. Best wishes and thanks again for sharing.
Thank you for your response. No I havent tried Milk of Magnesia I will look into it. What was the effect of procalopride you didnt like. I am nervous of taking it. Be well.
Try tryphalla. Also had gall bladder removed and had cycle of slow motility and then cramps and diarrhoea as result of Dulcolax and similar. I came across tryphalla on this site and take a capsule a day and it has made the wotld of difference, and no side effects.
and it came back normal. I had at least one bowel movement every day, so I feel like it was a waste of time.
My doctor initially explained that I would ingest a capsule every day for a few days before they conducted the test. (If I had known the test would be the one described in the link, I would have said no.) But since I have at least one bowel movement daily, by the fourth day, there were no markers left to detect. My doctor mentioned that some of his patients still had markers remaining, but they suffered from diarrhea.
I also tried prucalopride in two different forms. Prucalopride 2mg gave me diarrhea the first time I took it, but that side effect went away. While it did provide some relief from bloating, it caused a constant, painful feeling of hunger. The other form, Resolor 1mg, caused severe cramping and diarrhea. I ended up stopping both.
Thank you. Clearly you too have been through a lot, hard work isnt it getting digestion back on track. Pleased you feel in controL of your digestion now.
It's a nightmare... Unfortunately, I'm still not in control, and I can't see how I ever will be—but I'm trying. I think my main issue is partly bile-related, and just taking some supplements for bile issues won't be enough.
Do you think your issues are nerve-related? I also have some trapped nerves, including the pudendal nerve, and I have pelvic floor dysfunction.
Sorry to hear you are struggling still too. Absolutely I know my symptoms are nerve related. The brain gut axis is so complicated. I too have had a trapped epigastric nerve called ACNES - anterior cutaneous nerve entrapment syndrome. Took my four years to find a top london neurogastroenterologist who diagnosed the pain in one examination.
I was referred to my local teaching hospital pain centre who said the procedure proposed had no proof of value and they woudnt do it. I was distraught. A few weeks later a new lady pain consultant contacted me and said she would do it also on the nhs. I was injected under deep xray and within twenty minutes the four year anguish of pain was over never to return.
So yes our enteric nervous system is complicated. Visceral pain and nerve pain is awful and faulty functioning is a nightmare. Finding a medic or medics with forward thinking is like wading through treacle. Find one if you can and hang onto them. Unfortunately my lovely pain consultant has since emigrated to Australia a tad too far to follow. Wishing you all the very best.
Hi, like you I’m unable to go at all without stimulant laxatives. I was diagnosed with IBS/C and slow motility after several tests including CT scan and transit test where nearly all of the markers remained in my colon. I am currently prescribed 2mg Prucalopride and 5-10mg Dulcolax which has some effect but I still continue to have problems. Dulcolax gives me awful cramps and diarrhoea, Prucalopride initially gave me bad headaches for around 7-10 days I’m not sure if it helps with the constipation or not but my gastroenterologist says to continue taking as unable to offer me anything else. It’s all trial and error I’m afraid, I hope it helps you let us know how you get on x
Thank you. Wow that is a heavy amount of meds but pleased it is giving you some relief. I havent had any of the tests you have had. Hope to get tests asap. Did medics say what had caused the issues in the first place.
Not really my consultant just said that a lot of people with IBS have a different gut microbiome to other people and might benefit from probiotics. He recommended Symprove which is expensive but I bought a 3 month supply and took it for 10 weeks and my bloating and general discomfort was even worse so I stopped it. I have tried a number of other probiotics including Probio 7 from Boots and Alflorex but nothing seems to make a difference. It’s a constant struggle and very disheartening. I hope you manage to get tested and find something that works for you x
Thank you and so sorry you are struggling too. Its an ongoing battle to cope and stay on top of it. Who knew gastric issues were so complicated when they malfunction all bets are off. We just have to do the best we can ongoing. So disheartening sometimes. When I have a good day I am so appreciative of it. Take care.
I’ve been using Prucalopride for a few years now , it is not a laxative, it is a prokinetic so it should help you , don’t be put off by what other people say , it has served me well & we must remember in all the things we try that no one person is the same as the other , we all react differently to medication . Good luck , give it a try
Thank you and I am so pleased it is working for you. Tough old game to crack isnt it, no easy solutions. Long may procalopride give you relief. I am trying to get my head around prokinetics and how they work on the body. Stay well,
I have been using Quafora …an irrigation system …. It has been amazing but after almost 6months it is not working as well. I am still, grateful for it but I will often be left with some poo and I feel like I haven’t emptied my bowel. Just lost now as to how to continue because I don’t know what to do. At the moment I am eating two kiwis that are supposed to help you go
Quafora, right, thank you I will look into that. The irrigation system I have been given is huge and cumbersome to take away with me. It looks more like an instrument of torture. I thought there must be something more discrete in this day and age. I am pleased yours is giving you some relief. Mine is an NHS kit is yours or it it bought privately.
I tried bowel retraining and it did absolutely nothing for me. They told me about the two kiwi fruits a day then said oh but you cant eat them due to your chronic reflux. One step forward, two steps back. Wishing you well and success however you can achieve it. PS just looked at Quafora and it looks far more useable, thanks again.
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