Mebeverine stopped working?

[iOwlface]

Hi everyone,

Just wanted to pick your brains. I know I've not been online for a while but things haven't been too bad. Now I'm not sure what's causing symptoms to flare again whether it's the change in weather, the fact I'm snacking a lot due to my job and caring for mum or what. Basically I but put on Mebeverine 135 tablets 3x a day last year because I couldn't keep anything in for any length of time. I tapered off because I know they're short term meds and I was getting a little backed up, but one tablet on a morning seemed to be doing the trick, until this last few weeks.. I've had a few instances of the trots completely out of the blue (i put one down to overindulgence of flapjacks) but the other has perplexed me.

If it continues I'll go see the GP again, just wondering if anyone else has done this with mebeverine? And if going back up to the full dose has helped at all? I know there's probably a fair few factors playing here but it's taken about a year to get my appetite back to what it was and I really don't want to go back down that road again. I literally lost 2 stone in 2 to 3 months last time and I'm still not back to what I was in the first place so if I lose that again I'll look emaciated.

TIA!

[drax83]

I used mebeverine, or similar colofac when diagnosed in the seventies. There really outdated now. By the nineties they were both useless to help my symptoms. Settled down with buscapam now. It helps 75% of the time, but not always. I tend to trust it as radiologists now give you some before certain scans and other ct colonoscopys. Medical professionals should really be doing more work on effective treatment and medicines to reign in IBS symptoms.

[Bradstock]

I take mebeverine regularly plus half a loperimide tablet but I often need to adjust the dose - usually reducing .But then increase again when necessary. If you have reduced your dose then up it again for a while.

[Chloeblue]

Hi I’ve had 35 yrs of really unpredictable bowel problems, which seem to be getting worse with age. Loads of tests which always come back clear, so labelled IBS. I really think invasive tests do us no good, so I’m currently using buscopan and silicol gel (Holland &Barrett). I always flare badly with stress but it’s inevitable that things in life will happen . It’s only now they’re realising the connection with the gut and brain. IBS leads to anxiety which I turn leads to IBS. My first GP told me this, the only one who understood the effect of living with this awful condition that basically spoils our lives. The Mebeverine made me worse

[Johny334 in reply to Chloeblue]

hi

Do you take Buscopan before or after meals ?and how many do you take each day ?iv just started on it ,was on a trial of Amitriptyline but couldn’t tolerate the side effects 🙈

[Chloeblue in reply to Johny334]

Hi doesn’t matter when you take it. I couldn’t take amytriptyline. Totally different medication . I take it as and when required. I never take any meds on an empty stomach though

[Glitterpants]

I have taken mebrevine for a few years on prescription & Dr told me its ok to take long term. However, I would think you need to up the dose to recommended 3 a day until your bowels get back to normal.

[bungi1961]

I have been on the same tablets ( mebeverine ) for the last 18 months/2 years in my case I am so scared not to take them even on my good days as I got this Diverticular Diease/IBS and if I don't take them I am forever scared of the problems coming back to attack me like it does every day but now I can't sit stand walk as when I try to sit it feels like I am sat on rocks and I feel like something is stuck up there and now I am afraid to fart so keep on having to hold them in so keep on being on & off the toilet each time that I do as I am scared that the stuff will come out of me if I don't it's not until people like us really understands what we go through 365 days a year do they? when we are in constant pain and agony and in fear of what will come out each time that we do go toilet and how long we might be when we go!!! Well after my 2 colonoscopies that I had been told what was wrong that they would give me tablets things would be OK and things would go back to normal how wrong was I? as it's now 3 almost 4 years and I still got this awful problem I just wish it was!!! Well take care of yourself and look after yourself SORRY I can't be of any use