PPI Rebound: I took Pantoprazole 40mg for... - IBS Network

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PPI Rebound

ss017 profile image
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I took Pantoprazole 40mg for 1 month. I stopped taking it almost 2 weeks ago and have been experiencing some burning in my chest along with indigestion.

How long do the rebound effects usually last?

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ss017
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6 Replies

Can be several month. What I found that helped me was taking digestive enzymes with large meals and Zantac as needed. Pre and probiotics also. I live in the US and the easiest on my gut for enzymes and probiotics is a brand called Pure Encapsualtions.

Good Luck! Based on recent studies it seems a good idea to go off.

May I ask why you have stopped taking Pantoprazole?

ss017 profile image
ss017 in reply to

Mostly the side effects. I also didn’t want to take it long term anyway

in reply to ss017

Are you not worried that your symptoms will start up again??? Did the side effects outweigh the benefits?? I guessing they did.

I’m only intrigued as I have been on pantoprazole for 3 weeks now. For the past week I have felt the best I have for ages.

Can you tell me why you were on pantoprazole in the first place & what the side effects were you suffered. If you’d rather not discuss then I understand!!

M x

ss017 profile image
ss017 in reply to

I never had the burning sensation before taking the medication. I think i had what is called “silent reflux” because i never had any symptoms (as far as acid-related) yet my endoscopy showed inflammation. I had the endoscopy because of a shaking sensation in my chest along with some other symptoms. My doctor wanted me to be on the Pantoprazole for 3 months to let my stomach and esophagus heal, but i didn’t feel well on the medication. I was nauseous and not able to eat very much which made me feel even worse/weak. I also know that there are longterm side effects to these medications and i was only planning on taking it short term. I felt better once I got off as far as being able to eat again. The burning i found out was the rebound effect of getting of it. That is great that it has helped you! I guess medications just affect people differently

in reply to ss017

Thank you for your reply. I have had a problem whereas sometimes when I eat it’s like a plug in my oesophagus & nothing will go down & I have to run to the loo & bring my food back up. People have said ‘have a drink’ but that literally just sits aswell & everything comes back up. I used to get this every few months but since December it has been much worse & has become a daily occurrence. My gp put me on lansoprazole but nothing changed. As I said in my previous post I am now 3 weeks into pantoprazole and for the past week I haven’t had a recurrence on my ‘choking’. I’m going for a barium swallow on Tuesday to see if they can find an answer for me. Like you, I don’t particularly feel comfortable being on these drugs for a long period of time!! I feel so much better though right now that I think I will panic if I’m taken off them.

I really appreciate you taking the time to fill me in on your condition.

M x

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