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Zytiga
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Slowly rising PSA - Your Thoughts Wanted
I'm now on the Magnitude study (
Zytiga
, Pred and either Niraparab or placebo). Been on for 7 months. My PSA was 11.6 when I started
Zytiga
. It dropped to 3.5 but over the past 7 months, it has slowly increased (4.0, 6.0, 6.1, 7.9, 9.5, 12.1).
I'm now on the Magnitude study (
Zytiga
, Pred and either Niraparab or placebo). Been on for 7 months. My PSA was 11.6 when I started
Zytiga
. It dropped to 3.5 but over the past 7 months, it has slowly increased (4.0, 6.0, 6.1, 7.9, 9.5, 12.1).
davebliz
in
Advanced Prostate Cancer
3 years ago
Side effects of Zytiga and prednisolone
My concern is that these may be signs of PC spread, not simply temporary side effects of the
Zytiga
and prednisolone.
My concern is that these may be signs of PC spread, not simply temporary side effects of the
Zytiga
and prednisolone.
Arcticfox44
in
Advanced Prostate Cancer
3 years ago
BCR and PSA increasing...or not? <.05, 0.15, 0.29, 0.16
Thanks to all who shared comments after I posted that my PSA was increasing after a few years of undetectable readings (following RALP and then adjuvant EBRT and ADT+
Zytiga
for 18 mo, all after GS 4+3, PSA ~14, pT2n0m0).
Thanks to all who shared comments after I posted that my PSA was increasing after a few years of undetectable readings (following RALP and then adjuvant EBRT and ADT+
Zytiga
for 18 mo, all after GS 4+3, PSA ~14, pT2n0m0).
PGDuan
in
Advanced Prostate Cancer
3 years ago
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Cabazitaxel dosage & frequency?
(History: diagnosed November 2018 with metastatic Stage 4; began Docetaxel November, 2018 with Lupron ( PSA reduced from high teens to .5 ); lupron continues; Jan 2019 began
Zytiga
which led to doubling PSA most months for 6 months. ; stopped & began Xofigo for three cycles with a PSA at least doubling
(History: diagnosed November 2018 with metastatic Stage 4; began Docetaxel November, 2018 with Lupron ( PSA reduced from high teens to .5 ); lupron continues; Jan 2019 began
Zytiga
which led to doubling PSA most months for 6 months. ; stopped & began Xofigo for three cycles with a PSA at least doubling
baltha
in
Advanced Prostate Cancer
3 years ago
Help please
My complaint is they put him on
Zytiga
and Zometa. Shouldn’t he be moving forward with chemo??
My complaint is they put him on
Zytiga
and Zometa. Shouldn’t he be moving forward with chemo??
Survivor1965
in
Advanced Prostate Cancer
3 years ago
When is Provenge indicated?
My husband's doctor has not recommended, and declined our request for, any additional drugs like
Zytiga
because he has not demonstrated metastases, but we intend to find another doctor. We plan to try to get an appointment with Dr. Sartor at Tulane.
My husband's doctor has not recommended, and declined our request for, any additional drugs like
Zytiga
because he has not demonstrated metastases, but we intend to find another doctor. We plan to try to get an appointment with Dr. Sartor at Tulane.
SuppWife
in
Advanced Prostate Cancer
3 years ago
Zytiga
ZYTIGA
worked for a while and then stopped working. My oncologist moved me to other medicines. They all seem to work for a while and then stop.
ZYTIGA
worked for a while and then stopped working. My oncologist moved me to other medicines. They all seem to work for a while and then stop.
Yogi8
in
Advanced Prostate Cancer
3 years ago
Biospy results
Xtandi worked for 3 months and he took 6 doses of dosetaxel but new metastasises occured Doctor reccomended fondatione one cdx gen test and zytiga.if
zytiga
doesn’t work he is going to start on lutesium. Should we do the gen test ? Any suggestions?
Xtandi worked for 3 months and he took 6 doses of dosetaxel but new metastasises occured Doctor reccomended fondatione one cdx gen test and zytiga.if
zytiga
doesn’t work he is going to start on lutesium. Should we do the gen test ? Any suggestions?
Perfetto-Zeynep
in
Advanced Prostate Cancer
3 years ago
Advanced Prostate Cancer Update and Xgeva
So with that I have been 20 months with ADT using bicaludimide tablets each day ( after becoming allergic to
Zytiga
) and Lupron Shots each month. Took PSA down to 1.75 lowest and now 2.0.
So with that I have been 20 months with ADT using bicaludimide tablets each day ( after becoming allergic to
Zytiga
) and Lupron Shots each month. Took PSA down to 1.75 lowest and now 2.0.
Hidden
in
Advanced Prostate Cancer
2 years ago
Zytiga &Dexamethasone or what?
Do you know any case that
Zytiga
with Prednisone initially does not work for that person, but
Zytiga
with Dexamethasone works for him? Some people shared that when
Zytiga
with Prednisone worked at first and when its effectiveness reduced, they took
Zytiga
with Dexamethasone.
Do you know any case that
Zytiga
with Prednisone initially does not work for that person, but
Zytiga
with Dexamethasone works for him? Some people shared that when
Zytiga
with Prednisone worked at first and when its effectiveness reduced, they took
Zytiga
with Dexamethasone.
Hidden
in
Advanced Prostate Cancer
3 years ago
Hypertension Medications and Dementia
And for those on
Zytiga
and predisone who are having blood-presssure issues and are taking med to counter act, it might be worth while having a conversation with you cardiologist if a change would be worth while. https://www.ahajournals.org/doi/abs/10.1161/HYPERTENSIONAHA.121.17049
And for those on
Zytiga
and predisone who are having blood-presssure issues and are taking med to counter act, it might be worth while having a conversation with you cardiologist if a change would be worth while. https://www.ahajournals.org/doi/abs/10.1161/HYPERTENSIONAHA.121.17049
Hidden
in
Advanced Prostate Cancer
3 years ago
Zytiga & Low Fat Breakfast
Starting
Zytiga
tomorrow, and MO wants me to try the "low fat breakfast" regimen. Trouble is, there don't appear to be guidelines for what constitutes a "low fat breakfast" -- I read the original study and they didn't control for that.
Starting
Zytiga
tomorrow, and MO wants me to try the "low fat breakfast" regimen. Trouble is, there don't appear to be guidelines for what constitutes a "low fat breakfast" -- I read the original study and they didn't control for that.
LifeQuality
in
Advanced Prostate Cancer
3 years ago
My Jeff ❤️ Staples out and update
Kwon said the scans currently “override” the rise in PSA as it appears the
Zytiga
/Prednisone is doing its job! We are kinda in limbo until mid October. They are going to restage Jeff. He is scheduled for additional labs, a PET scan, and MRI of his abdomen.
Kwon said the scans currently “override” the rise in PSA as it appears the
Zytiga
/Prednisone is doing its job! We are kinda in limbo until mid October. They are going to restage Jeff. He is scheduled for additional labs, a PET scan, and MRI of his abdomen.
Pancake_Lefse
in
Advanced Prostate Cancer
3 years ago
UTI mimics ADT side effects?
I sort of remember that the first few months of ADT (firmagon and
zytiga
and prednisone) were not that bad. Then things really began to decline, very little energy and muscle weakness. This recently climaxed to the point that I was considering suicide.
I sort of remember that the first few months of ADT (firmagon and
zytiga
and prednisone) were not that bad. Then things really began to decline, very little energy and muscle weakness. This recently climaxed to the point that I was considering suicide.
spencoid2
in
Advanced Prostate Cancer
3 years ago
Keytruda update
Completed chemo, provenge,
Zytiga
, Xtandi and an ARV 110 trial. Currently on Lupron and keytruda. A second Foundation One DNA test showed high mutational burden with mmr 2 and 6, cdk 12 and pten loss. As a result his MO started him on keytruda.
Completed chemo, provenge,
Zytiga
, Xtandi and an ARV 110 trial. Currently on Lupron and keytruda. A second Foundation One DNA test showed high mutational burden with mmr 2 and 6, cdk 12 and pten loss. As a result his MO started him on keytruda.
Faith1111
in
Advanced Prostate Cancer
3 years ago
Lu-177 switch from Xofigo. How long an interval?
History: I have stage 4 PCa diagnosed 2.5 years ago and have had Docetaxel ( 5 sessions), Lupron (continuously),
Zytiga
( failed), and now Xofigo( 3 sessions with monthly doubling PSA).
History: I have stage 4 PCa diagnosed 2.5 years ago and have had Docetaxel ( 5 sessions), Lupron (continuously),
Zytiga
( failed), and now Xofigo( 3 sessions with monthly doubling PSA).
baltha
in
Advanced Prostate Cancer
3 years ago
DepoProvera for Lupron SEs--many questions
On my MO's recommendation, I've started DepoProvera [DP] injections to combat serious sleep deprivation and other side-effects of Lupron/
Zytiga
. So far, I've had 3 shots, roughly a month apart. It really helps!
On my MO's recommendation, I've started DepoProvera [DP] injections to combat serious sleep deprivation and other side-effects of Lupron/
Zytiga
. So far, I've had 3 shots, roughly a month apart. It really helps!
LifeQuality
in
Advanced Prostate Cancer
3 years ago
Joint and leg pain!!!
But my theory is that the joint pain could be due to the chemo, lupron,
Zytiga
, etc! So isn’t that really cancer pain? Some of those meds do deplete joint lubricant? Thank you for your suggestions!
But my theory is that the joint pain could be due to the chemo, lupron,
Zytiga
, etc! So isn’t that really cancer pain? Some of those meds do deplete joint lubricant? Thank you for your suggestions!
Cynthgob
in
Advanced Prostate Cancer
3 years ago
Brief, intense radiation and hormone therapy for very high risk prostate cancer
They added a short course of Erleada and
Zytiga
to just 6 months of Lupron. I think they erred in not treating the pelvic lymph nodes. https://www.prostatecancer.news/2021/06/brief-intense-radiation-and-hormone.html
They added a short course of Erleada and
Zytiga
to just 6 months of Lupron. I think they erred in not treating the pelvic lymph nodes. https://www.prostatecancer.news/2021/06/brief-intense-radiation-and-hormone.html
Tall_Allen
in
Prostate Cancer Network
3 years ago
Info on Xofigo
Lupron 15 months then
Zytiga
added! Exgeva started at diagnosis. PSA never went to single digits! Rising over last 6 months. March 29th 308.47 April 26th 312.34 May 24th 346.60
Zytiga
stopped in May pain has increased maybe just coincidence.
Lupron 15 months then
Zytiga
added! Exgeva started at diagnosis. PSA never went to single digits! Rising over last 6 months. March 29th 308.47 April 26th 312.34 May 24th 346.60
Zytiga
stopped in May pain has increased maybe just coincidence.
Yorkielover2
in
Advanced Prostate Cancer
3 years ago
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