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Any Data or MO Advice Regarding Dutasteride / Finasteride At Very Early Biochemical Recurrence?
Does anyone know of any studies or MO advice they've gotten regarding use of Dutasteride or Finasteride at very early signs of Biochemical Reccurrence (uPSA in the 0.03 - 0.1 range) prior to Salvage Radiotherapy? It's obviously going to slow PSA doubling time and thereby probably lengthen the time
Does anyone know of any studies or MO advice they've gotten regarding use of Dutasteride or Finasteride at very early signs of Biochemical Reccurrence (uPSA in the 0.03 - 0.1 range) prior to Salvage Radiotherapy? It's obviously going to slow PSA doubling time and thereby probably lengthen the time
jazj
in
Advanced Prostate Cancer
7 months ago
PSA Response From Broccoli Sprout Extract (Sulforaphane) May Due To Just Being Moderate ADT
I forgot I ran across this a 2 years ago as many with PCa diagnosis are very interested in Sulforaphane due to a lot of excitement from a few studies a few years ago. (This fueled an explosion of supplements on Amazon.) This however is one of the more expensive supplements and my jury is still out
I forgot I ran across this a 2 years ago as many with PCa diagnosis are very interested in Sulforaphane due to a lot of excitement from a few studies a few years ago. (This fueled an explosion of supplements on Amazon.) This however is one of the more expensive supplements and my jury is still out
jazj
in
Advanced Prostate Cancer
7 months ago
Declining psa #9
Gm folks, hope all are having a wonderful New Year. I’m following up n giving results on using ivermectin, cbd oil, turmeric Vit b3,6,12 Vit c And zinc solely after eliminating ADT after 7 months, post Rp n rad… Psa dropped another .29 points to .66 down from .95 n psa was hovering 7 when I first got
Gm folks, hope all are having a wonderful New Year. I’m following up n giving results on using ivermectin, cbd oil, turmeric Vit b3,6,12 Vit c And zinc solely after eliminating ADT after 7 months, post Rp n rad… Psa dropped another .29 points to .66 down from .95 n psa was hovering 7 when I first got
Nfler
in
Advanced Prostate Cancer
7 months ago
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Transitioning from NDT to T3 (slowly) - anyone done this? Or combines NDT with t3?
Hello there, After many years unsuccessfully on Levo, then NDT, NDT+T4, I'm trying NDT and T3...and it's tricky. My timing might be incorrect, I take now 3 daily doses and I'm feeling overmedicated in the afternoon (tight chest, dizzy, weird energy, hunger, sweaty feet, blurry vision etc.). I take
Hello there, After many years unsuccessfully on Levo, then NDT, NDT+T4, I'm trying NDT and T3...and it's tricky. My timing might be incorrect, I take now 3 daily doses and I'm feeling overmedicated in the afternoon (tight chest, dizzy, weird energy, hunger, sweaty feet, blurry vision etc.). I take
Incoguto
in
Thyroid UK
7 months ago
Searching fot NDT (natural thyroid hormone)
Hello I have been on NDT for over 20 years now, originally Canadian version then when they stop manufacturing, got it through compound pharmacy (various experiences, some better that others), lately I am on Armour. The problem is, that not only it's very expensive but also there are long delays with
Hello I have been on NDT for over 20 years now, originally Canadian version then when they stop manufacturing, got it through compound pharmacy (various experiences, some better that others), lately I am on Armour. The problem is, that not only it's very expensive but also there are long delays with
Yellow_tulip
in
Thyroid UK
7 months ago
Recent thyroid blood tests results are different ?
I usually have low TSH results as I am taking Armour natural desiccated thyroid (NDT) but this time the results from the surgery show serum TSH level (XaELV) as 16.8miu/L (0.34-5.6) - speaking to GP on Thursday any advice ? Been feeling ok tho always difficulty Going to sleep and losing weight - recently
I usually have low TSH results as I am taking Armour natural desiccated thyroid (NDT) but this time the results from the surgery show serum TSH level (XaELV) as 16.8miu/L (0.34-5.6) - speaking to GP on Thursday any advice ? Been feeling ok tho always difficulty Going to sleep and losing weight - recently
Montheone
in
Thyroid UK
7 months ago
Stratification test for ADT effectiveness
As someone who has had the awful experience of ADT side effects, I give this tool a standing ovation: https://artera.ai/arteraai-prostate-cancer-test Just approved for Medicare coverage, and just a matter of time before California and New York join the other 48 states in approving it.
As someone who has had the awful experience of ADT side effects, I give this tool a standing ovation: https://artera.ai/arteraai-prostate-cancer-test Just approved for Medicare coverage, and just a matter of time before California and New York join the other 48 states in approving it.
ron_bucher
in
Advanced Prostate Cancer
7 months ago
SRBT and EXTEND trial
Does anybody have the full text of EXTEND trial results from June 2023? (my payment attempt is rejected and the tips on how to get a study without cost doesn´t work) https://pubmed.ncbi.nlm.nih.gov/37022702/ Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic
Does anybody have the full text of EXTEND trial results from June 2023? (my payment attempt is rejected and the tips on how to get a study without cost doesn´t work) https://pubmed.ncbi.nlm.nih.gov/37022702/ Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic
Purple-Bike
in
Advanced Prostate Cancer
7 months ago
thyroid s supplier
I’ve been on t3 for 18 months (non converter). Had severe hair loss & itchy eyes. Wasn’t sure why - thot menopause! After everyone talking about TR NDT I was going through nhs files & found 3 months worth (at time my adrenals were smashed so thought non working TR was dodgy stopped taking it). In 6
I’ve been on t3 for 18 months (non converter). Had severe hair loss & itchy eyes. Wasn’t sure why - thot menopause! After everyone talking about TR NDT I was going through nhs files & found 3 months worth (at time my adrenals were smashed so thought non working TR was dodgy stopped taking it). In 6
joydot
in
Thyroid UK
7 months ago
What is the next step
I have one more Immunotherapy for my bladder cancer, so far all scan have shown no metastasis. Now I need to focus on my PC after more than a year of ignoring it. My PSA has been fluctuating and is now 0.65, doubling time is 16 months, I have not had ADT yet and my MO wants to just wait and watch. What
I have one more Immunotherapy for my bladder cancer, so far all scan have shown no metastasis. Now I need to focus on my PC after more than a year of ignoring it. My PSA has been fluctuating and is now 0.65, doubling time is 16 months, I have not had ADT yet and my MO wants to just wait and watch. What
old64horn
in
Advanced Prostate Cancer
7 months ago
Follow up to "My trajectory after a 'vacation' and a new metastasis," and a new question
I though that the recommendation of the "tumor board" at Smilow Cancer Center in New Haven, CT, would be "doublet therapy" to treat the new metastasis that was found with a PET PSMA scan, (the second one that was found after my Lupron "vacation"; the first was treated with radiation--details of my case
I though that the recommendation of the "tumor board" at Smilow Cancer Center in New Haven, CT, would be "doublet therapy" to treat the new metastasis that was found with a PET PSMA scan, (the second one that was found after my Lupron "vacation"; the first was treated with radiation--details of my case
Istomin
in
Advanced Prostate Cancer
7 months ago
New blood results are confusing - what to do?
Hello people, please could you advise what I should do as the Medichecks thyroid results (finger prick 9 Jan) are showing TSH 0.005(0.27-4.2) FT3 5.8(3.1-6.8) FT4 18.1(12-22) Thyroglob antibodies 16.1(0-115) Thyroid Perox antibodies 9.2(0-34). Previous Genova test in september 23 showed TSH 3.27(0.40
Hello people, please could you advise what I should do as the Medichecks thyroid results (finger prick 9 Jan) are showing TSH 0.005(0.27-4.2) FT3 5.8(3.1-6.8) FT4 18.1(12-22) Thyroglob antibodies 16.1(0-115) Thyroid Perox antibodies 9.2(0-34). Previous Genova test in september 23 showed TSH 3.27(0.40
wiseoldwoman
in
Thyroid UK
7 months ago
ASCO 2023: AI-Derived Digital Pathology Biomarker Predicts Benefit of Long-Term ADT with Radiotherapy in Localized High-Risk Prostate Cancer
https://www.urotoday.com/conference-highlights/asco-2023/asco-2023-prostate-cancer/144902-asco-2023-development-and-validation-of-an-ai-derived-digital-pathology-based-biomarker-to-predict-benefit-of-long-term-androgen-deprivation-therapy-with-radiotherapy-in-men-with-localized-high-risk-prostate-cancer-across-multiple-phase-iii-nrg-rtog-trials.html
https://www.urotoday.com/conference-highlights/asco-2023/asco-2023-prostate-cancer/144902-asco-2023-development-and-validation-of-an-ai-derived-digital-pathology-based-biomarker-to-predict-benefit-of-long-term-androgen-deprivation-therapy-with-radiotherapy-in-men-with-localized-high-risk-prostate-cancer-across-multiple-phase-iii-nrg-rtog-trials.html
zeitgeistxx
in
Advanced Prostate Cancer
7 months ago
Short-term vs Long-Term ADT for High Risk Men
Here's a review of a recent presentation at ASCO 2023 by Artera.ai regarding the use of Artificial Intelligence analysis of biopsy slides to predict which high-risk men do or don't benefit from short-term ADT vs long-term ADT. Their findings are summarized here: [i]"Based on these results, it appears
Here's a review of a recent presentation at ASCO 2023 by Artera.ai regarding the use of Artificial Intelligence analysis of biopsy slides to predict which high-risk men do or don't benefit from short-term ADT vs long-term ADT. Their findings are summarized here: [i]"Based on these results, it appears
janebob99
in
Prostate Cancer Network
7 months ago
Managing OAB after proton RT
Hello everyone, This 73 year old treated an unfavorable intermediate localized PCa with 28 fractions of proton radiation, completed on Dec. 15th. Completed a 4 months course of oral Orgovyx on Dec. 28th. The side effects of the ADT were hot flashes (tolerable) and loss of libido. The side effects
Hello everyone, This 73 year old treated an unfavorable intermediate localized PCa with 28 fractions of proton radiation, completed on Dec. 15th. Completed a 4 months course of oral Orgovyx on Dec. 28th. The side effects of the ADT were hot flashes (tolerable) and loss of libido. The side effects
old_reliable
in
Prostate Cancer Network
7 months ago
Help and advice please
Hi I just wondered if anyone had any advice that might help me please I have attached my latest NHS blood test results, I am taking NDT thyroid medication called NP. Which at the moment I have started alternating for example one and then one and a half grain every other day. I have seen endocrinologist's
Hi I just wondered if anyone had any advice that might help me please I have attached my latest NHS blood test results, I am taking NDT thyroid medication called NP. Which at the moment I have started alternating for example one and then one and a half grain every other day. I have seen endocrinologist's
Bess48
in
Thyroid UK
7 months ago
Will T return?
As I near the end of my 2 years of ADT (Lupron + Abi), I am curious if I should expect a return of Testosterone. I would love to regain my libido and endurance. But after 2 years, I don't know what to expect. My MO has been pretty vague about what to expect. Another issue is that I didn't have a
As I near the end of my 2 years of ADT (Lupron + Abi), I am curious if I should expect a return of Testosterone. I would love to regain my libido and endurance. But after 2 years, I don't know what to expect. My MO has been pretty vague about what to expect. Another issue is that I didn't have a
jmarsh
in
Advanced Prostate Cancer
7 months ago
PSA 6 months after RT
Here is a review of a presentationby Dr. Ravi at ASCO 2023, regarding measuring the PSA at 6 months post radiation treatment, for all risk groups. He found that the 6-month post-RT PSA was highly prognostic of 5- and 10-year rates of metastasis free survival (MFS), Overall Survival (OS), and prostate
Here is a review of a presentationby Dr. Ravi at ASCO 2023, regarding measuring the PSA at 6 months post radiation treatment, for all risk groups. He found that the 6-month post-RT PSA was highly prognostic of 5- and 10-year rates of metastasis free survival (MFS), Overall Survival (OS), and prostate
janebob99
in
Prostate Cancer Network
7 months ago
In hospital take ndt
Hi. Just a question regarding hospital stays and taking unprescribed ndt. I am probably going to be in hospital soon and am wondering what the heck to do about my thyroid s. I ended up in A&E with chest pains and was put on a ward where they took my antibiotics off me and put them in a locked cupboard
Hi. Just a question regarding hospital stays and taking unprescribed ndt. I am probably going to be in hospital soon and am wondering what the heck to do about my thyroid s. I ended up in A&E with chest pains and was put on a ward where they took my antibiotics off me and put them in a locked cupboard
Catlover3
in
Thyroid UK
7 months ago
Testosterone was nearly back to normal, then dropped
I had a year of Lupron and Enzalutamide in 2022. Testosterone slowly came back to a high of about 240 in June and Sept 2023. Normal for me is around 350 - 375. Now this week T is down to 156. Is this sort of fluctuation normal? I had 6 months of ADT in connection with radiation for recurrent PCa
I had a year of Lupron and Enzalutamide in 2022. Testosterone slowly came back to a high of about 240 in June and Sept 2023. Normal for me is around 350 - 375. Now this week T is down to 156. Is this sort of fluctuation normal? I had 6 months of ADT in connection with radiation for recurrent PCa
Teddy28
in
Advanced Prostate Cancer
7 months ago
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