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Vital Role of B12 and Folate
https://www.sciencedirect.com/science/article/abs/pii/S0193953X12001001?via%3Dihub This article focuses on the role of b12 and folate in the synthesis of methionine and one of the side effects of improper synthesis is depression and cognitive impairment. However, I want to emphasise that poor synthesis
https://www.sciencedirect.com/science/article/abs/pii/S0193953X12001001?via%3Dihub This article focuses on the role of b12 and folate in the synthesis of methionine and one of the side effects of improper synthesis is depression and cognitive impairment. However, I want to emphasise that poor synthesis
B12life
in
Pernicious Anaemia Society
6 months ago
Help with my husband's results he is really struggling
I am so grateful to everyone on this forum as I have now been officially diagnosed with Hashimotos after going privately and opted for Armour NDT so next bloods will be first on meds and supplements. I wonder if I could get some wisdom on my husband's results. He has been ill for years now which was
I am so grateful to everyone on this forum as I have now been officially diagnosed with Hashimotos after going privately and opted for Armour NDT so next bloods will be first on meds and supplements. I wonder if I could get some wisdom on my husband's results. He has been ill for years now which was
Susanmcg
in
Thyroid UK
6 months ago
Folate when SI?
Hi everyone, How much folate is recommended when injecting B12? The folate tablets I have are 400µg. Also, can anyone kindly comment on my sudden lip problems? I awoke 4 mornings ago to blistered lips, they were slightly worse the next morning. The blistering seems to have stopped but my lips are
Hi everyone, How much folate is recommended when injecting B12? The folate tablets I have are 400µg. Also, can anyone kindly comment on my sudden lip problems? I awoke 4 mornings ago to blistered lips, they were slightly worse the next morning. The blistering seems to have stopped but my lips are
J972
in
Pernicious Anaemia Society
6 months ago
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is this a sign my meds are struggling or just how it is now?
Sorry for the long message but would appreciate knowing if this is typical or if I am being a little dramatic and unrealistic. diagnosed with RA nearly 2 years ago. Took a while but pretty much back to normal after moving to injecting 20mg MTX, 200g hydroxy and folic acid 6 days a week. Took just over
Sorry for the long message but would appreciate knowing if this is typical or if I am being a little dramatic and unrealistic. diagnosed with RA nearly 2 years ago. Took a while but pretty much back to normal after moving to injecting 20mg MTX, 200g hydroxy and folic acid 6 days a week. Took just over
Newbie73
in
NRAS
6 months ago
Getting myself in a hell of a muddle!
I have been on levothyroxine for 10+ years and never had a problem (well not since the early years) - I have been getting along nicely on a dose of 75 for the last few years. I was at the GP's a few weeks ago about something not related to my thyroid and happened to mention in the conversation that
I have been on levothyroxine for 10+ years and never had a problem (well not since the early years) - I have been getting along nicely on a dose of 75 for the last few years. I was at the GP's a few weeks ago about something not related to my thyroid and happened to mention in the conversation that
Loobs39
in
Thyroid UK
6 months ago
Early signs of PA
I've been giving some thought to how long I've had PA. I was diagnosed about 2 years ago. BUT, when i look back at old photos of myself, my skin colour changed to be quite yellowy (my mum says my dad and his mum both had the yellowy skin tone). This yellowy colour has faded out and I'm much more "white
I've been giving some thought to how long I've had PA. I was diagnosed about 2 years ago. BUT, when i look back at old photos of myself, my skin colour changed to be quite yellowy (my mum says my dad and his mum both had the yellowy skin tone). This yellowy colour has faded out and I'm much more "white
Sailinglady
in
Pernicious Anaemia Society
6 months ago
Suppression of TSH but low T4/T3 levels whilst taking Levo/Lio Combo
A few years ago, my thyroid results were looking a lot better but NHS GP over the last 2 years has told me to reduce my dosage twice (because of the 'risks' of overtreatment). I'm now on 100mcg levothyroxine (75mcg supplied by GP and topped up by myself) and 25mcg liothyronine (self-sourced). I now don't
A few years ago, my thyroid results were looking a lot better but NHS GP over the last 2 years has told me to reduce my dosage twice (because of the 'risks' of overtreatment). I'm now on 100mcg levothyroxine (75mcg supplied by GP and topped up by myself) and 25mcg liothyronine (self-sourced). I now don't
Louise1610
in
Thyroid UK
4 months ago
B12 supplementation query
My active B12 level in 2022 was 66.1 pmol/L and following advice on our wonderful forum I began taking Thorne basic B complex. This raised my levels to 78.6 pmol/L in 2023. This year my B12 level is 76.3 pmol/L. So it hasn't continued to increase to the recommended 100 pmol/L. For the past ten days
My active B12 level in 2022 was 66.1 pmol/L and following advice on our wonderful forum I began taking Thorne basic B complex. This raised my levels to 78.6 pmol/L in 2023. This year my B12 level is 76.3 pmol/L. So it hasn't continued to increase to the recommended 100 pmol/L. For the past ten days
goingholiday
in
Thyroid UK
27 days ago
Interesting article on more sustainable B12 production
[i]"Research at the Quadram Institute has developed sustainable manufacturing processes for B12, helping address a growing global need for the synthesised vitamin."[/i] The article addresses the issues with high production costs and environmental damage from B12 production, and also mentions CluB-12.
[i]"Research at the Quadram Institute has developed sustainable manufacturing processes for B12, helping address a growing global need for the synthesised vitamin."[/i] The article addresses the issues with high production costs and environmental damage from B12 production, and also mentions CluB-12.
Technoid
in
Pernicious Anaemia Society
6 months ago
Hubby and his heart
My husband had bad flu over Christmas and since then has had huge issues with breathlessness, bloating, fluid retention and fatigue. He's had ECG's, MRI , chest x-ray and bloods. This has shown up that he has fluid around his heart as it's just not pumping properly, is severely anaemic and his vitamin
My husband had bad flu over Christmas and since then has had huge issues with breathlessness, bloating, fluid retention and fatigue. He's had ECG's, MRI , chest x-ray and bloods. This has shown up that he has fluid around his heart as it's just not pumping properly, is severely anaemic and his vitamin
Muzzyduck
in
British Heart Foundation
6 months ago
Sylvia Plath and B12?
Has anyone else pondered on the links here? Although I can find all sorts of discussion about her early stresses, repeated losses and struggle with depression, even chemical imbalances, possible bipolar, not a jot can I find about the B12 deficiency which she would have had at least at one point, even
Has anyone else pondered on the links here? Although I can find all sorts of discussion about her early stresses, repeated losses and struggle with depression, even chemical imbalances, possible bipolar, not a jot can I find about the B12 deficiency which she would have had at least at one point, even
bookish
in
Pernicious Anaemia Society
6 months ago
Once I start supplementing B12, will my B12 blood tests still be accurate?
I would like to know if blood tests will still be a useful measure of my B12 levels, once I have started supplementing B12. I would be testing active B12. The reason I ask is that I have read pernicious anemia people saying that once they start injections (and supplements too maybe), that the B12 blood
I would like to know if blood tests will still be a useful measure of my B12 levels, once I have started supplementing B12. I would be testing active B12. The reason I ask is that I have read pernicious anemia people saying that once they start injections (and supplements too maybe), that the B12 blood
Carrie234
in
Thyroid UK
28 days ago
Update and latest results
Hello again lovely people. I thought I’d come back and update having been on Levo 50mcg since diagnosis 3 months ago. In early January the GP asked me to retest and only TSH was done (big let down but not unexpected)! I was amazed that after only 2 months on Levo 50mcg that my TSH had dropped to 0.44
Hello again lovely people. I thought I’d come back and update having been on Levo 50mcg since diagnosis 3 months ago. In early January the GP asked me to retest and only TSH was done (big let down but not unexpected)! I was amazed that after only 2 months on Levo 50mcg that my TSH had dropped to 0.44
Gardeningaddict
in
Thyroid UK
6 months ago
Ducks in a row
I was first diagnosed with Pernicious anaemia 3 or 4 years ago but thought nothing of it until my legs and arms started going numb and I kept falling round the place and had difficulty walking and getting up from a fallen or seated position. I now am aware of how serious it is, I've stopped drinking
I was first diagnosed with Pernicious anaemia 3 or 4 years ago but thought nothing of it until my legs and arms started going numb and I kept falling round the place and had difficulty walking and getting up from a fallen or seated position. I now am aware of how serious it is, I've stopped drinking
Whiteways4711
in
Pernicious Anaemia Society
6 months ago
B12 ampules
Why do I have more aches and pains the closer I bring my injection together.also what is the most effective b12
Why do I have more aches and pains the closer I bring my injection together.also what is the most effective b12
Mozza127
in
Pernicious Anaemia Society
30 days ago
Monitoring when starting Folic Acid and Ferrous fumerate
Hi guys, my Folate wa only midly low, been prescribed Folic Acid and GP just said I can make an appointment in a couple of months "if I want to" Reading on the NICE website, I see it says the following What monitoring is required after treatment for vitamin B12 or folate deficiency has started? Perform
Hi guys, my Folate wa only midly low, been prescribed Folic Acid and GP just said I can make an appointment in a couple of months "if I want to" Reading on the NICE website, I see it says the following What monitoring is required after treatment for vitamin B12 or folate deficiency has started? Perform
yewotc23
in
Thyroid UK
3 months ago
Do I just learn to live with thinning hair?
I was diagnosed with Hashimotos in 1997 & was on thyroxine for 17 years.Then on T3-only for about 4 years,after testing positive for the D102 variant from both parents. I have been on NDT for a few years now-THIROID at first until its supply issues.I got on very well with TR MANN & was very disappointed
I was diagnosed with Hashimotos in 1997 & was on thyroxine for 17 years.Then on T3-only for about 4 years,after testing positive for the D102 variant from both parents. I have been on NDT for a few years now-THIROID at first until its supply issues.I got on very well with TR MANN & was very disappointed
Naomi8
in
Thyroid UK
6 months ago
Why is iron over-range yet TIBC shows a need ro take more please?
I'm wondering if the following could be explained please?In past ferritin has been 48 ug/L & obv considered normal by Dr. On doing private iron profile results like the following have come up,on more than one occasion. Iron 24.19 (6,6,-22) Tibc 115.49 (41-77) Transferrin saturation 20.95% (20-55) Kind
I'm wondering if the following could be explained please?In past ferritin has been 48 ug/L & obv considered normal by Dr. On doing private iron profile results like the following have come up,on more than one occasion. Iron 24.19 (6,6,-22) Tibc 115.49 (41-77) Transferrin saturation 20.95% (20-55) Kind
Jo5454
in
Pernicious Anaemia Society
3 months ago
Newly diagnosed and confused
Hello, thank you for having me. I have been diagnosed with hyperthyroidism and due to administrative errors, have had limited treatment. I am now under the care of Endocrinology but am struggling to understand my results. Please could someone shed some light on what's happening? Upon reflection,
Hello, thank you for having me. I have been diagnosed with hyperthyroidism and due to administrative errors, have had limited treatment. I am now under the care of Endocrinology but am struggling to understand my results. Please could someone shed some light on what's happening? Upon reflection,
Opposite
in
Thyroid UK
6 months ago
Recent blood results, help interpreting
Hi everyone, I haven't posted in a while, but would like my latest blood results checked with the knowledgable people on here. I've been on a treatment of 125mcg of Levothyroxine and alternating days of 5mcg and 7mcg of liothyronine. I have been feeling better on this dose, and was slightly too highly
Hi everyone, I haven't posted in a while, but would like my latest blood results checked with the knowledgable people on here. I've been on a treatment of 125mcg of Levothyroxine and alternating days of 5mcg and 7mcg of liothyronine. I have been feeling better on this dose, and was slightly too highly
thyroidqueen12
in
Thyroid UK
6 months ago
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