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A bit of help to understand results, please. Was given the option of upping thyroxine dose to 100mg from 50mg, or going with 2g of NDT. Also told I have very low vitamin d Waiting on my medication being dispensed but in the mean time I started taking the vitd that I got from holland and barret. Don't
A bit of help to understand results, please. Was given the option of upping thyroxine dose to 100mg from 50mg, or going with 2g of NDT. Also told I have very low vitamin d Waiting on my medication being dispensed but in the mean time I started taking the vitd that I got from holland and barret. Don't
Bigfraz76
in
Thyroid UK
1 year ago
Looking for suggestion of clinical trials for mCRPC
I have had SBRT (2007), Chemotherapy (2010/2011), ADT using Casodex/Lupron/Zytiga (2012-Current). Interested in joining trials that involve PARP inihibitors, immunotherapy, or other new/novel therapies. Can any of you suggest trials currently accepting candidates. My PSA was undetectable (<0.01) for
I have had SBRT (2007), Chemotherapy (2010/2011), ADT using Casodex/Lupron/Zytiga (2012-Current). Interested in joining trials that involve PARP inihibitors, immunotherapy, or other new/novel therapies. Can any of you suggest trials currently accepting candidates. My PSA was undetectable (<0.01) for
Cmdrdata
in
Advanced Prostate Cancer
1 year ago
NDT source
hi all, I have emailed admin for a list of endocrinologists who might prescribe NDT in the UK. And NDT suppliers. I used to live in Bangkok where Pharma used to produce Thiroyd. It was approx £10 for 1000 tablets. I moved back to the UK and ran out of NDT. The pandemic hit and Pharma stopped manufacturing
hi all, I have emailed admin for a list of endocrinologists who might prescribe NDT in the UK. And NDT suppliers. I used to live in Bangkok where Pharma used to produce Thiroyd. It was approx £10 for 1000 tablets. I moved back to the UK and ran out of NDT. The pandemic hit and Pharma stopped manufacturing
Stasia51
in
Thyroid UK
1 year ago
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8 Month Follow up Report from Lu-J591
Results as reflected in PSA downward trend continues to impress! Current PSA is 0.030 down 80% from pre-treatment level. Reviewing: I am mHSPC, lymph node only to pelvis and abdomen. No bone involvement. Diagnosed in 2007 Gl 4+3. RARP had ECE, SVI and positive margins. Underwent docetaxel and prostate
Results as reflected in PSA downward trend continues to impress! Current PSA is 0.030 down 80% from pre-treatment level. Reviewing: I am mHSPC, lymph node only to pelvis and abdomen. No bone involvement. Diagnosed in 2007 Gl 4+3. RARP had ECE, SVI and positive margins. Underwent docetaxel and prostate
MateoBeach
in
Fight Prostate Cancer
1 year ago
Enzalutamide (Xtandi) or not
2012 Robotic Prostatectomy. Gleason 3+4 2015 Salvage Radiation plus 6 months Zoladex 2019 and 2020 PET/CT scans showed 2 mets to spine and one in Ribs plus several in left back lymph nodes. 2020 Rising PSA to 11.8 with 2 mets to spine and one in Ribs plus several in left back lymph nodes 2021 (March
2012 Robotic Prostatectomy. Gleason 3+4 2015 Salvage Radiation plus 6 months Zoladex 2019 and 2020 PET/CT scans showed 2 mets to spine and one in Ribs plus several in left back lymph nodes. 2020 Rising PSA to 11.8 with 2 mets to spine and one in Ribs plus several in left back lymph nodes 2021 (March
x-rays1
in
Advanced Prostate Cancer
1 year ago
Lupron+docetaxel+Abiraterone
First time posting. I have stage IVB PC, which was discovered via a hernia procedure in November 2022. I completed 1 month of ADT with no side effects and my PSA dropped to 1.0. Met with my Oncologist today and he proposed changing my treatment to mirror the CHAARTED clinical trial (Lupron+Docetaxel
First time posting. I have stage IVB PC, which was discovered via a hernia procedure in November 2022. I completed 1 month of ADT with no side effects and my PSA dropped to 1.0. Met with my Oncologist today and he proposed changing my treatment to mirror the CHAARTED clinical trial (Lupron+Docetaxel
TMcgee
in
Advanced Prostate Cancer
1 year ago
T4 - T3 relations 🤝
hello brainiacs - a little Q for the big brains here. could anyone explain to me why T4 goes down⬇️ when T3 goes up ⬆️? For instance… Results on 1 grain Armour NDT (equivalent:
38mcg T4, 9mcg T3
) TSH: 8.41 [u]
T4: 11.8 (12-22)
[/u] T3: 4.1 Results on 1.5 grains Armour NDT (equivalent
hello brainiacs - a little Q for the big brains here. could anyone explain to me why T4 goes down⬇️ when T3 goes up ⬆️? For instance… Results on 1 grain Armour NDT (equivalent:
38mcg T4, 9mcg T3
) TSH: 8.41 [u]
T4: 11.8 (12-22)
[/u] T3: 4.1 Results on 1.5 grains Armour NDT (equivalent
Hidden
in
Thyroid UK
1 year ago
ART Systematic Review of the Decipher® Genomic Classifier in Prostate Cancer
Decipher genomic testing can help determine who will not benefit from ADT treatment thereby sparing them from side effects. When combined with SOC testing it increase predictive accuracy for who will have metastisis (MET) by 85-90%. Both biopsy and clinical specimens can be used. I had my Decipher
Decipher genomic testing can help determine who will not benefit from ADT treatment thereby sparing them from side effects. When combined with SOC testing it increase predictive accuracy for who will have metastisis (MET) by 85-90%. Both biopsy and clinical specimens can be used. I had my Decipher
RMontana
in
Active Surveillance - Prostate Cancer
1 year ago
Thyroid S NDT and Anxiety
hi all. I’ve just started talking NDT Thyroid S after a while on ERFA. I’ve been on it for about a week easing up the dose but feel a little anxious. Nothing major just a little undercurrent of worry, and the odd twinge or nerves I wouldn’t expect. anyone had this??
hi all. I’ve just started talking NDT Thyroid S after a while on ERFA. I’ve been on it for about a week easing up the dose but feel a little anxious. Nothing major just a little undercurrent of worry, and the odd twinge or nerves I wouldn’t expect. anyone had this??
HashiFedUp
in
Thyroid UK
1 year ago
Only ADT + Apalutamide as treatment
My dad has Gleason 4+5 prostate cancer. He is newly diagnosed and he started ADT one month ago. According to CT it is widely metastatic in lymph nodes. Bone scan is clear. He will start apalutamide but they said that no radiation and no cytostatic treatment. I am horrified because I thought at least
My dad has Gleason 4+5 prostate cancer. He is newly diagnosed and he started ADT one month ago. According to CT it is widely metastatic in lymph nodes. Bone scan is clear. He will start apalutamide but they said that no radiation and no cytostatic treatment. I am horrified because I thought at least
Daughter17
in
Advanced Prostate Cancer
1 year ago
Stage 4
Had 18 Chemo treatments, 20 radiation, on ADT from Start, PSA not readable after 22 months. Dr advises to stop ADT, to improve lifestyle. Not sure if this will increase risk of return sooner?
Had 18 Chemo treatments, 20 radiation, on ADT from Start, PSA not readable after 22 months. Dr advises to stop ADT, to improve lifestyle. Not sure if this will increase risk of return sooner?
Natvega
in
Advanced Prostate Cancer
1 year ago
raising the topic of a hormone holiday after July
visit to London MO today for more hormones ( switched to 3 month Zolodex because last months Degarelix injection is still a nasty swollen red lump on my stomach) I picked up my Apalutamide and had blood tests as ever with a face to face consult. I decided to ‘soft land’ the subject of a hormone holiday
visit to London MO today for more hormones ( switched to 3 month Zolodex because last months Degarelix injection is still a nasty swollen red lump on my stomach) I picked up my Apalutamide and had blood tests as ever with a face to face consult. I decided to ‘soft land’ the subject of a hormone holiday
Brysonal
in
Fight Prostate Cancer
1 year ago
Timings to take NDT and best time for blood draw advice please
Hi, just wondered if I’ve been doing the right protocol for taking my meds and also timings for bloods drawn! I split dose 2x day… no food 4 hours before and 1 hour after…could I leave smaller gap before with NDT… food wise please?? Finding it really hard as don’t have regular sleep patterns and just
Hi, just wondered if I’ve been doing the right protocol for taking my meds and also timings for bloods drawn! I split dose 2x day… no food 4 hours before and 1 hour after…could I leave smaller gap before with NDT… food wise please?? Finding it really hard as don’t have regular sleep patterns and just
Blanche1960
in
Thyroid UK
1 year ago
How do I take this further to get my liothyronine tablets?
I've been emailing back and forth to my surgery but they said the ICB have decided I can't have liothyronine tablets instead of the cheaper capsules.I had a prescription filled in December and started the Roma brand liothyronine capsules on 26th December 22. On the 27th December I came out in a rash
I've been emailing back and forth to my surgery but they said the ICB have decided I can't have liothyronine tablets instead of the cheaper capsules.I had a prescription filled in December and started the Roma brand liothyronine capsules on 26th December 22. On the 27th December I came out in a rash
Locky1971
in
Thyroid UK
1 year ago
ADT now failing, what is next for us. ?
After 2 years of Trelstar my husbands PSA is now 2. He had RP in 2011, with PSA 32,followed by IRT. No symptoms at all now, no sideeffects from ADT which took PSA to 0. Small rise in blood pressureHas anybody survived for a lenghty time adding a new ADT drug? Should he have chemo? He is 75 years old,
After 2 years of Trelstar my husbands PSA is now 2. He had RP in 2011, with PSA 32,followed by IRT. No symptoms at all now, no sideeffects from ADT which took PSA to 0. Small rise in blood pressureHas anybody survived for a lenghty time adding a new ADT drug? Should he have chemo? He is 75 years old,
tasmanien13
in
Advanced Prostate Cancer
1 year ago
Post chemo resensitivity to hormonal treatment
I have read here that Zytiga or Xtandi may be tried after chemo despite resistance having developed pre-chemo to one of them. Does anyone have a reference to anything in the literature about this? Thank you
I have read here that Zytiga or Xtandi may be tried after chemo despite resistance having developed pre-chemo to one of them. Does anyone have a reference to anything in the literature about this? Thank you
spw1
in
Advanced Prostate Cancer
1 year ago
CVD & GnRH agonists/antagonists
New study below [1]. Men with PCa have a greater risk of death from cardiovascular [CV] events, and androgen deprivation therapy [ADT] further increases that risk. The study looked at ADT drugs that target gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland. The drugs were Degarelix
New study below [1]. Men with PCa have a greater risk of death from cardiovascular [CV] events, and androgen deprivation therapy [ADT] further increases that risk. The study looked at ADT drugs that target gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland. The drugs were Degarelix
pca2004
in
Fight Prostate Cancer
1 year ago
Best Weight Training for Hormone therapy
Long time lurker having been on A/S for 8 years. Now at 3+4 (5% or less) and will be undergoing SBRT soon. My team says I should do at least 4-6 months of ADT and i know weight training can help while on ADT. I am 71 and because of covid don't want to do training in a gym. Any suggestions on what sort
Long time lurker having been on A/S for 8 years. Now at 3+4 (5% or less) and will be undergoing SBRT soon. My team says I should do at least 4-6 months of ADT and i know weight training can help while on ADT. I am 71 and because of covid don't want to do training in a gym. Any suggestions on what sort
hrdc69
in
Prostate Cancer And Gay Men
1 year ago
When to stop ADT post RT given the situation and moderate hypofractionated RT
first apologies in advance for the long post - my wife keeps telling me to edit before I bombard everyone including medics! I am trying to gather information to aid my decision when I meet my oncologist in a few weeks to discuss the way forward. I finished Moderately hypofactionated Radiotherapy just
first apologies in advance for the long post - my wife keeps telling me to edit before I bombard everyone including medics! I am trying to gather information to aid my decision when I meet my oncologist in a few weeks to discuss the way forward. I finished Moderately hypofactionated Radiotherapy just
SimMartin
in
Advanced Prostate Cancer
1 year ago
ART Outcomes Of Salvage Radiotherapy (sRT) For Recurrent Prostate Cancer (PCa) After Radical Prostatectomy (RP)
84 Chinese patients with prostate cancer treated with SRT to the prostatic fossa alone during 2006-2017 at Tuen Mun Hospital, Hong Kong Results: Median SRT dose given was 70 Gy (range, 64-76 Gy). Median pre-SRT PSA level was 0.4 ng/mL (0.2-7.4 ng/mL). After SRT, 47 (56%) patients had undetectable
84 Chinese patients with prostate cancer treated with SRT to the prostatic fossa alone during 2006-2017 at Tuen Mun Hospital, Hong Kong Results: Median SRT dose given was 70 Gy (range, 64-76 Gy). Median pre-SRT PSA level was 0.4 ng/mL (0.2-7.4 ng/mL). After SRT, 47 (56%) patients had undetectable
RMontana
in
Active Surveillance - Prostate Cancer
1 year ago
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