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Small lymphocytic lymphoma (SLL)
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CT scan series part 10 - Clinical Trial CT scan Context
CT scan series part 10 - Clinical Trial CT scan Context There is solid rationale for CT-scanning in a Clinical Trial setting that cannot be avoided but is it adequate or overkill? Who decides? There are so many newer drugs that promise better efficacy with less toxicity that it is hard to keep up with
CT scan series part 10 - Clinical Trial CT scan Context There is solid rationale for CT-scanning in a Clinical Trial setting that cannot be avoided but is it adequate or overkill? Who decides? There are so many newer drugs that promise better efficacy with less toxicity that it is hard to keep up with
ThreeWs
in
CLL Support
10 years ago
CT scan series part 5 – A bit about CT scanners
Let's first define some terms. I don't want to lose you in the detail of sievert (Sv) vs gray (Gy) as units of radiation measurement because there is no meaningful way you can calculate your individual risk based on adding up sources of ionizing radiation. Any assessment of risk must be done by statistical
Let's first define some terms. I don't want to lose you in the detail of sievert (Sv) vs gray (Gy) as units of radiation measurement because there is no meaningful way you can calculate your individual risk based on adding up sources of ionizing radiation. Any assessment of risk must be done by statistical
ThreeWs
in
CLL Support
10 years ago
CT scan series part 4 - Everything needs context
But aren't we living with ionizing radiation all the time so what's the big deal? Correct, the average yearly exposure of a US resident is 3 to 3.2 mSv (milli sievert). Brian Koffman who spends much of his time at 30 thousand feet flying all over the place to bring us great interviews is probably getting
But aren't we living with ionizing radiation all the time so what's the big deal? Correct, the average yearly exposure of a US resident is 3 to 3.2 mSv (milli sievert). Brian Koffman who spends much of his time at 30 thousand feet flying all over the place to bring us great interviews is probably getting
ThreeWs
in
CLL Support
10 years ago
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Has anyone here successfully treated Diffuse Large B Cell lymphoma using CVP-R, minus the Vincristine?
My mother had one round of CHOP-R, but it affected her heart so adversely the doctor won't administer it anymore as he is afraid she might not survive through it. (So, she will continue with CVP-R, minus the Vincristine.) As a result he says we are no longer treating to cure, but to relieve symptoms
My mother had one round of CHOP-R, but it affected her heart so adversely the doctor won't administer it anymore as he is afraid she might not survive through it. (So, she will continue with CVP-R, minus the Vincristine.) As a result he says we are no longer treating to cure, but to relieve symptoms
Hidden
in
Lymphoma Canada
10 years ago
There's lots happening in Adoptive T-cell transfer technology cancer research - CAR-T being just one aspect
When Dr Carl June of the University of Pennsylvania, used chimeric antigen receptor (CAR) technology to provide an amazing cure in a CAR-T trial in 2011 for three CLL patients that had pretty well run out of options http://www.uphs.upenn.edu/news/News_Releases/2011/08/t-cells/ there were valid concerns
When Dr Carl June of the University of Pennsylvania, used chimeric antigen receptor (CAR) technology to provide an amazing cure in a CAR-T trial in 2011 for three CLL patients that had pretty well run out of options http://www.uphs.upenn.edu/news/News_Releases/2011/08/t-cells/ there were valid concerns
AussieNeil
Partner
in
CLL Support
10 years ago
SLL and prognostic indicators
I'm reading articles which suggest that the chromosomal abnormalities of SLL are different from CLL, most especially absence of 17p del and prevalence of Trisomy 12. Does anyone know anything about this?
I'm reading articles which suggest that the chromosomal abnormalities of SLL are different from CLL, most especially absence of 17p del and prevalence of Trisomy 12. Does anyone know anything about this?
Hidden
in
CLL Support
10 years ago
Treatment of My Father suffering from CLL with Endoxan (Cyclophosphamide) and Bendit--Bendamustine Hydrochloride.
My father was diagnosed CLL- Chronic Lymphocytic Leukemia on 03-Sep-2013 through a bone marrow. The values of %LYM = 80 % with WBC= 511,000. We have consulted an oncologist for the treatment. He has started Chemotherapy with Endoxan (Cyclophosphamide) and did 06 Cycles of chemo (Each after 21-Days)
My father was diagnosed CLL- Chronic Lymphocytic Leukemia on 03-Sep-2013 through a bone marrow. The values of %LYM = 80 % with WBC= 511,000. We have consulted an oncologist for the treatment. He has started Chemotherapy with Endoxan (Cyclophosphamide) and did 06 Cycles of chemo (Each after 21-Days)
nadeemnaz4190
in
CLL Support
10 years ago
Explainer: What is Cancer Immunotherapy?
Nial Wheate, Senior Lecturer in Pharmaceutical Chemistry at the University of Sydney, Australia, provides an introductory overview of the sophisticated ways we now use immunotherapy including vaccinations, antibodies (proteins that bind to foreign objects to mark them for destruction), cytokines (molecules
Nial Wheate, Senior Lecturer in Pharmaceutical Chemistry at the University of Sydney, Australia, provides an introductory overview of the sophisticated ways we now use immunotherapy including vaccinations, antibodies (proteins that bind to foreign objects to mark them for destruction), cytokines (molecules
AussieNeil
Partner
in
CLL Support
10 years ago
Hypothyroidism - advice on levels
Hi I asked for my thyroid levels to be tested again and once again they came back normal. I asked the nurse what the actual levels are and she told me 0.74. I know that here in the UK they can come back 'normal' and still be regarded as low by the standards of other countries eg in the US they can
Hi I asked for my thyroid levels to be tested again and once again they came back normal. I asked the nurse what the actual levels are and she told me 0.74. I know that here in the UK they can come back 'normal' and still be regarded as low by the standards of other countries eg in the US they can
Kirby
in
Fibromyalgia Action UK
10 years ago
Does anyone get meds for hair loss due to the meds like regaine I would think some ladies will but docs tend not to with blokes I think
Cos the cellcept seems to make it recede but the consultant is fobbing me off So would like some info to have a heated discuss with
Cos the cellcept seems to make it recede but the consultant is fobbing me off So would like some info to have a heated discuss with
glasgowguy
in
LUPUS UK
10 years ago
Is Chemotherapy necessary even when the tumor is small and not spread to Axillary lymph nodes?
My mother(53 years had lumptectomy and a tumor of about 3.5 x 3 cms was removed. The biopsy report says negative on the Axillary nodes.. so the cancer has not spread to other parts as I understand that Axillary lymph nodes are first which receive the drainage form the breast. The Onco surgeon has recommended
My mother(53 years had lumptectomy and a tumor of about 3.5 x 3 cms was removed. The biopsy report says negative on the Axillary nodes.. so the cancer has not spread to other parts as I understand that Axillary lymph nodes are first which receive the drainage form the breast. The Onco surgeon has recommended
fatehkhan
in
Breast Cancer India
10 years ago
ASH 2013: Dr. Jeff Sharman Discusses FCR versus BR in CLL
Hi Friends On my blog today http://bkoffman.blogspot.com I share my ASH interview with Dr. Sharman where we discussed the data on FCR versus BR. While this is less the exciting news it would have been a few years back before the emerging era of targeted therapies,, it is still important for a significant
Hi Friends On my blog today http://bkoffman.blogspot.com I share my ASH interview with Dr. Sharman where we discussed the data on FCR versus BR. While this is less the exciting news it would have been a few years back before the emerging era of targeted therapies,, it is still important for a significant
bkoffman
CLL CURE Hero
in
CLL Support
10 years ago
new to group
Been told I am now classified as having
small
lymphocytic
lymphoma
. on a side note cll runs in my family, Dad was diagnosed aged 73( late stage)died aged 78, uncle ( dads brother) diagnosed aged 60 and my 1st cousin ( Uncles son) diagnosed aged 47.
Been told I am now classified as having
small
lymphocytic
lymphoma
. on a side note cll runs in my family, Dad was diagnosed aged 73( late stage)died aged 78, uncle ( dads brother) diagnosed aged 60 and my 1st cousin ( Uncles son) diagnosed aged 47.
fisaunders
in
CLL Support
10 years ago
Blood work is back.. I have not talked to the doctor yet but. im guessing shes going to say i am fine
WBC4.2 RBC4.59 Hgb14.8 Hct43.9 MCV 95.8 MCH32.3 MCHC33.7 RDW12.6 Platelet Count218 MPV9.5 NEUTROPHILS %55.7 LYMPHOCYTES %37.3 MONOCYTES %5.3 EOSINOPHILS %0.9 BASOPHILS %0.8 NEUTROPHILS ABS2.3 LYMPHOCYTES ABS1.6 MONOCYTES ABSOLUTE0.2 EOSINOPHILS ABSOLUTE0.0 BASOPHILS ABS0.0
WBC4.2 RBC4.59 Hgb14.8 Hct43.9 MCV 95.8 MCH32.3 MCHC33.7 RDW12.6 Platelet Count218 MPV9.5 NEUTROPHILS %55.7 LYMPHOCYTES %37.3 MONOCYTES %5.3 EOSINOPHILS %0.9 BASOPHILS %0.8 NEUTROPHILS ABS2.3 LYMPHOCYTES ABS1.6 MONOCYTES ABSOLUTE0.2 EOSINOPHILS ABSOLUTE0.0 BASOPHILS ABS0.0
kkgirl
in
LUPUS UK
10 years ago
watch and wait
my 88yr old mother was diagnosed 3/2/2014 early stage cll.being sent for an ultrasound scan(abdomen).her blood readings are wcc14.2/ lymphocytes6.3 with monocytes 0.8.she suffers night sweats and has develped a cough(mucus).she will be sent for in 2/3 months.my question is ,if treatment is necessary,
my 88yr old mother was diagnosed 3/2/2014 early stage cll.being sent for an ultrasound scan(abdomen).her blood readings are wcc14.2/ lymphocytes6.3 with monocytes 0.8.she suffers night sweats and has develped a cough(mucus).she will be sent for in 2/3 months.my question is ,if treatment is necessary,
chrismac
in
CLL Support
10 years ago
My husband, Rick 66 y, has refractory DLBC Lymphoma. He has had front line and salvage chemos: RCHOP, RICE, GEMOX, HC-VAD, Rituxan/Revlimid.
These chemos have kept the cancer at bay but none have been successful with remission or PR. Rick has just started Treanda/Rituxan. After a week enlarged nodes in armpit and groin areas are shrinking. Severe lymphodema in arm and leg is going down rapidly. Would welcome comments, feedback and experiences
These chemos have kept the cancer at bay but none have been successful with remission or PR. Rick has just started Treanda/Rituxan. After a week enlarged nodes in armpit and groin areas are shrinking. Severe lymphodema in arm and leg is going down rapidly. Would welcome comments, feedback and experiences
janj13
in
Lymphoma Canada
10 years ago
Will this DNA checking technology enable us to kill cancerous cells while leaving healthy cells untouched?
We've heard of FISH (Fluorescence In Situ Hybridization) testing, where fluorescent probes are used to identify whether we have previously identified faulty (mutated) DNA sequences that are most likely responsible for us developing CLL. We also know that FISH prognostic testing can give us an indication
We've heard of FISH (Fluorescence In Situ Hybridization) testing, where fluorescent probes are used to identify whether we have previously identified faulty (mutated) DNA sequences that are most likely responsible for us developing CLL. We also know that FISH prognostic testing can give us an indication
AussieNeil
Partner
in
CLL Support
10 years ago
Dr Sharman on Relapsed Diffuse Large B Cell Lymphoma (DBLC)
Dr Sharman's latest blog looks at how R-CHOP became established as the most commonly used standard of care for DBLC (i.e. how patients fared better when rituximab was added to the existing CHOP therapy) and what options are available for relapsed DBLC patients. While not specifically relevant to CLL
Dr Sharman's latest blog looks at how R-CHOP became established as the most commonly used standard of care for DBLC (i.e. how patients fared better when rituximab was added to the existing CHOP therapy) and what options are available for relapsed DBLC patients. While not specifically relevant to CLL
AussieNeil
Partner
in
CLL Support
11 years ago
Dr Richard Furman reports on Idelalisib and Rituximab Phase III study outcomes at ASH2013
At the American Society of Hematology (ASH) 2003, Lead author Richard Furman, MD, reported that [i]"combination treatment with the PI3K-delta inhibitor idelalisib and rituximab (Rituxan) was associated with a >70% improvement in overall survival (OS) in patients with high-risk relapsed/refractory chronic
At the American Society of Hematology (ASH) 2003, Lead author Richard Furman, MD, reported that [i]"combination treatment with the PI3K-delta inhibitor idelalisib and rituximab (Rituxan) was associated with a >70% improvement in overall survival (OS) in patients with high-risk relapsed/refractory chronic
AussieNeil
Partner
in
CLL Support
11 years ago
iwCLL 2013: Dr. Michael Hallek Discusses Clinical Trials in Germany versus the USA and BR versus FCR
Hi friends, After a holiday break, I am back posting interviews about CLL on my blog: http://bkoffman.blogspot.com I line the way Prof. Hallek thinks about these issues Happy New Year to all. Brian
Hi friends, After a holiday break, I am back posting interviews about CLL on my blog: http://bkoffman.blogspot.com I line the way Prof. Hallek thinks about these issues Happy New Year to all. Brian
bkoffman
CLL CURE Hero
in
CLL Support
11 years ago
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