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Piperine and L-dopa producing probiotic
I recently ran across a couple of things about gut bacteria that I thought were interesting. The first involves the use of piperine (an extract of black pepper) to keep l-dopa from being converted to dopamine by bacteria in the small intestine, leaving more to travel to the brain; https://onlinelibrary.wiley.com
I recently ran across a couple of things about gut bacteria that I thought were interesting. The first involves the use of piperine (an extract of black pepper) to keep l-dopa from being converted to dopamine by bacteria in the small intestine, leaving more to travel to the brain; https://onlinelibrary.wiley.com
Rufous2
in
Cure Parkinson's
1 month ago
Afib medications
HiI've been reading all the posts for 5 years but never asked anything until today. I was diagnosed with lone perm afib 6 years ago, i was 64. I was totally asymtomatic but advised to take a anticoagulant and beta blocker. I tried a couple of anticoags before settling on eliquis. I could not tolerate
HiI've been reading all the posts for 5 years but never asked anything until today. I was diagnosed with lone perm afib 6 years ago, i was 64. I was totally asymtomatic but advised to take a anticoagulant and beta blocker. I tried a couple of anticoags before settling on eliquis. I could not tolerate
fodgreen
in
AF Association
1 year ago
pleural effusion
hi all you very supportive ladies . 4 years since my diagnosis with stage 3 ovarian cancer I have had all the chemo combinations available plus Avastin and PARP inhibitors . I was then in a clinical trial for a year which had a small effect and finished in March. a couple of weeks ago , I was admitted
hi all you very supportive ladies . 4 years since my diagnosis with stage 3 ovarian cancer I have had all the chemo combinations available plus Avastin and PARP inhibitors . I was then in a clinical trial for a year which had a small effect and finished in March. a couple of weeks ago , I was admitted
Lookingahead
in
My Ovacome
1 month ago
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Aspen Neuroscience to Present at International Society for Cell & Gene Therapy (ISCT) Annual Meeting
As part of the ISCT 2024 Translational Pathway Sessions, as well as the ISCT main program, Aspen's Chief Scientific Officer Xiaokui Zhang, Ph.D., and Chief Technology Officer Kim Raineri will discuss developments in autologous research and development, including for ANPD001, Aspen's autologous iPSC-derived
As part of the ISCT 2024 Translational Pathway Sessions, as well as the ISCT main program, Aspen's Chief Scientific Officer Xiaokui Zhang, Ph.D., and Chief Technology Officer Kim Raineri will discuss developments in autologous research and development, including for ANPD001, Aspen's autologous iPSC-derived
Farooqji
in
Cure Parkinson's
1 month ago
PROTACS: what they are and the good and bad of these molecules
Fascinating, and they are currently being tested also for degenerative diseases...they are a rather new technique...and yet we already have "advanced PROTACs", the speed of research is impressive... 1. PROTAC Mechanism Proteolysis-targeting chimeras (PROTACs) have emerged as a promising therapeutic
Fascinating, and they are currently being tested also for degenerative diseases...they are a rather new technique...and yet we already have "advanced PROTACs", the speed of research is impressive... 1. PROTAC Mechanism Proteolysis-targeting chimeras (PROTACs) have emerged as a promising therapeutic
Maxone73
in
Advanced Prostate Cancer
1 month ago
News from Malecare and OpenAI
Today, GPTs in the Store are now available to all ChatGPT users, allowing more than 100 million weekly active users to experience Cancer Copilot, Clinical Trial Navigator and the others in the store for free. Also, GPTs now use the newest flagship model, GPT-4o. Here are direct links: https://chatgpt.com
Today, GPTs in the Store are now available to all ChatGPT users, allowing more than 100 million weekly active users to experience Cancer Copilot, Clinical Trial Navigator and the others in the store for free. Also, GPTs now use the newest flagship model, GPT-4o. Here are direct links: https://chatgpt.com
Darryl
Partner
in
Prostate Cancer Network
1 month ago
news from Malecare and OpenAI
Today, GPTs in the Store are now available to all ChatGPT users, allowing more than 100 million weekly active users to experience Cancer Copilot, Clinical Trial Navigator and the others in the store for free. Also, GPTs now use the newest flagship model, GPT-4o. Here are direct links: https://chatgpt.com
Today, GPTs in the Store are now available to all ChatGPT users, allowing more than 100 million weekly active users to experience Cancer Copilot, Clinical Trial Navigator and the others in the store for free. Also, GPTs now use the newest flagship model, GPT-4o. Here are direct links: https://chatgpt.com
Darryl
Partner
in
Advanced Prostate Cancer
1 month ago
Wednesday's Word
[u][i]
Second line therapy
[/i][/u] [u][i][/i][/u]
This a term used In PBC a patient does not respond to Urso - usually within a year's time from the start of dosing. A different drug of choice is needed.
The only approved second line treatment is the use of Ovaliva (obeticholic acid
[u][i]
Second line therapy
[/i][/u] [u][i][/i][/u]
This a term used In PBC a patient does not respond to Urso - usually within a year's time from the start of dosing. A different drug of choice is needed.
The only approved second line treatment is the use of Ovaliva (obeticholic acid
DonnaBoll
Administrator
in
PBC Foundation
1 month ago
Interactive seminar on Garvan institute's work to improve the treatment of advanced cancers, including myeloma, breast and prostate cancer
Garvan Institute of Medical Research Free Public Seminar - Giving cancer no place to hide SPEAKER/S Professor Peter Croucher and Associate Professor Christine Chaffer DATE 10:30am 21 Jun 2024— 11:30am 21 Jun 2024 (AEST) Join us for an interactive seminar on Garvan’s work to improve the treatment
Garvan Institute of Medical Research Free Public Seminar - Giving cancer no place to hide SPEAKER/S Professor Peter Croucher and Associate Professor Christine Chaffer DATE 10:30am 21 Jun 2024— 11:30am 21 Jun 2024 (AEST) Join us for an interactive seminar on Garvan’s work to improve the treatment
Seasid
in
Advanced Prostate Cancer
1 month ago
Statins in older patients and their benefits
There is, not surprisingly, a lot of discussion here about us taking statins and one of the points often made is that there has been little evidence of benefit for over 75s - mainly because they are more often than not excluded from clinical trials. This is a patient summary of a Chinese study which
There is, not surprisingly, a lot of discussion here about us taking statins and one of the points often made is that there has been little evidence of benefit for over 75s - mainly because they are more often than not excluded from clinical trials. This is a patient summary of a Chinese study which
PMRpro
Ambassador
in
PMRGCAuk
1 month ago
Results from 4 Genomic labs
3 years ago we received a Foundation ONE Report giving us the report he has CDK12 mutation. He has been on Lupron, NUBEQA, and Zytiga. Over time they have failed. Recently, 4 lymph nodes were removed for thorough testing to make sure C had not mutated into Neuroendocrine. It had not. Actually, the
3 years ago we received a Foundation ONE Report giving us the report he has CDK12 mutation. He has been on Lupron, NUBEQA, and Zytiga. Over time they have failed. Recently, 4 lymph nodes were removed for thorough testing to make sure C had not mutated into Neuroendocrine. It had not. Actually, the
JolleySprings
in
Advanced Prostate Cancer
1 month ago
Allopregnanolone as a Regenerative Treatment for Parkinson's Disease (Allo-PD)
I just happened upon this trial and it is something I had never heard of. It looks like a very small trial being conducted in Tucson, AZ. https://clinicaltrials.gov/study/NCT06263010?locStr=Arizona&country=United%20States&state=Arizona&cond=Parkinson%20disease&aggFilters=status:not%20rec&rank=2 Detailed
I just happened upon this trial and it is something I had never heard of. It looks like a very small trial being conducted in Tucson, AZ. https://clinicaltrials.gov/study/NCT06263010?locStr=Arizona&country=United%20States&state=Arizona&cond=Parkinson%20disease&aggFilters=status:not%20rec&rank=2 Detailed
Boscoejean
in
Cure Parkinson's
1 month ago
Next NoSilverBullet webinar on 17th of June: Sackner-Bernstein, MD, on "Why I am optimistic that we might now have a Silver Bullet for PD".
I am delighted to announce that our next NoSilverBullet Zoom webinar will be taking place at 7.30pm London time on Monday, the 17th of June. Jonathan Sackner-Bernstein, MD, will be talking to us about "Why I am optimistic that we might now have a Silver Bullet for PD". Please use the Eventbrite link
I am delighted to announce that our next NoSilverBullet Zoom webinar will be taking place at 7.30pm London time on Monday, the 17th of June. Jonathan Sackner-Bernstein, MD, will be talking to us about "Why I am optimistic that we might now have a Silver Bullet for PD". Please use the Eventbrite link
Michel0220
in
Cure Parkinson's
1 month ago
why didn't you consider a clinical trial?
Please help me understand more about the barriers to participating in clinical trials. If you've ever considered joining a clinical trial but decided against it, please share what influenced your decision?
Please help me understand more about the barriers to participating in clinical trials. If you've ever considered joining a clinical trial but decided against it, please share what influenced your decision?
Darryl
Partner
in
Prostate Cancer And Gay Men
1 month ago
why didn't you consider a clinical trial?
Please help me understand more about the barriers to participating in clinical trials. If you've ever considered joining a clinical trial but decided against it, please share what influenced your decision?
Please help me understand more about the barriers to participating in clinical trials. If you've ever considered joining a clinical trial but decided against it, please share what influenced your decision?
Darryl
Partner
in
Advanced Prostate Cancer
1 month ago
Flax Seeds and A-fib
Hi everyone, I was thinking of introducing milled flax seeds in to my diet as a health thing after watching a programme on them. However, after doing a Google search I am finding that certain sites are pointing towards it not being a good thing when on Anticoagulants. I’m on Apixiban,Bisoprolol and digoxin
Hi everyone, I was thinking of introducing milled flax seeds in to my diet as a health thing after watching a programme on them. However, after doing a Google search I am finding that certain sites are pointing towards it not being a good thing when on Anticoagulants. I’m on Apixiban,Bisoprolol and digoxin
Ailsablue
in
AF Association
1 year ago
clinical trial
hi. Just wondering if anyone is on the clinical trial at Dana Farber in Boston with verzenio and oserdu? Thanks. Marianne
hi. Just wondering if anyone is on the clinical trial at Dana Farber in Boston with verzenio and oserdu? Thanks. Marianne
marianne88
in
SHARE Metastatic Breast Cancer
1 month ago
exercise anxiety
I used to be a kean, regular runner and back in July 2020 I went running in extreme heat and didn’t feel as energised as normal and felt very lethargic and my heart rate showed readings of up to 208bpm and quite erratic. Again I just put this down to exhaustion. Anyway cutting a long story short, I felt
I used to be a kean, regular runner and back in July 2020 I went running in extreme heat and didn’t feel as energised as normal and felt very lethargic and my heart rate showed readings of up to 208bpm and quite erratic. Again I just put this down to exhaustion. Anyway cutting a long story short, I felt
Fondant
in
AF Association
1 year ago
New treatment
2 weeks ago I had liver ablation to remove 3 tumors on my liver. 2 were responding to treatment (anastrozole and kisqali for HER2 neg) and 1 was not. Surgery went well. Biopsy showed that the growing tumor was triple negative. Seemingly the other 2 (breast and hip met) are still HER2 negative. Anyone
2 weeks ago I had liver ablation to remove 3 tumors on my liver. 2 were responding to treatment (anastrozole and kisqali for HER2 neg) and 1 was not. Surgery went well. Biopsy showed that the growing tumor was triple negative. Seemingly the other 2 (breast and hip met) are still HER2 negative. Anyone
JulieB76
in
SHARE Metastatic Breast Cancer
1 month ago
Cancer Clinical Trial Participation May Not Actually Improve Survival, Study Says, MedPage Today May 22, 2024
[i]While an admittedly imperfect pooled analysis (w/ PCa trials amounting to 7% of total), this paper illuminates the effects of patient selection bias in clinical trial outcomes. [/i][i]
(emphasis is added.)
[/i][i] Along with the accompanying editorial, it should serve to provide some new guidance
[i]While an admittedly imperfect pooled analysis (w/ PCa trials amounting to 7% of total), this paper illuminates the effects of patient selection bias in clinical trial outcomes. [/i][i]
(emphasis is added.)
[/i][i] Along with the accompanying editorial, it should serve to provide some new guidance
cujoe
in
Fight Prostate Cancer
1 month ago
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