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Levodopa-Induced Euphoria and Addictions in Parkinson’s. It's of concern for people with neuropsychiatric fluctuations between ON and OFF.
I'm referencing a 2017 research article. Some people have more significant neuropsychiatric fluctuations between ON and OFF levodopa drug treatment states. These people seem to be more at risk for triggered addictive behavior and drug abuse. The conclusion of the abstract is "The psychostimulant effects
I'm referencing a 2017 research article. Some people have more significant neuropsychiatric fluctuations between ON and OFF levodopa drug treatment states. These people seem to be more at risk for triggered addictive behavior and drug abuse. The conclusion of the abstract is "The psychostimulant effects
ElliotGreen
in
Cure Parkinson's
4 years ago
Association of Autonomic Dysfunction With Disease Progression and Survival in Parkinson Disease. MSA.
Association of Autonomic Dysfunction With Disease Progression and Survival in Parkinson Disease. Discussion The main finding of the study is that earlier development of AutD or individual autonomic abnormalities (including orthostatic hypotension, urinary symptoms, upper gastrointestinal tract symptoms
Association of Autonomic Dysfunction With Disease Progression and Survival in Parkinson Disease. Discussion The main finding of the study is that earlier development of AutD or individual autonomic abnormalities (including orthostatic hypotension, urinary symptoms, upper gastrointestinal tract symptoms
aspergerian
in
Cure Parkinson's
4 years ago
Isothiocyanates, neuroinflammation, and Parkinson's
Isothiocyanates can reduce neuroinflammation by activating Nrf2 - a protein that regulates antioxidant defenses. Isothiocyanates such as sulforaphane can be obtained from the diet from cruciferous vegetables. Broccoli sprouts are a concentrated source of sulforaphane. Sources: Isothiocyanates Are Promising
Isothiocyanates can reduce neuroinflammation by activating Nrf2 - a protein that regulates antioxidant defenses. Isothiocyanates such as sulforaphane can be obtained from the diet from cruciferous vegetables. Broccoli sprouts are a concentrated source of sulforaphane. Sources: Isothiocyanates Are Promising
Rhyothemis
in
Cure Parkinson's
4 years ago
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EYE SPECIALIST FOR DIAGNOSIS?
I'm seeing an eye specialist in February and wonder if his observations might offer a more definite diagnosis of
Parkinsonism
, which is what I feel could be going on, either MSA or PSP.
I'm seeing an eye specialist in February and wonder if his observations might offer a more definite diagnosis of
Parkinsonism
, which is what I feel could be going on, either MSA or PSP.
rideabike
in
PSP Association
5 years ago
Febuxostat and Parkinson’s
Hi all this is my first post in the community. I am recently diagnosed with Parkinson’s, it seems to have manifested itself recently following a prolonged battle with gout and the use of febuxostat (about two years) Having recently researched possibilities of using a supplement like Manuka bean, it seems
Hi all this is my first post in the community. I am recently diagnosed with Parkinson’s, it seems to have manifested itself recently following a prolonged battle with gout and the use of febuxostat (about two years) Having recently researched possibilities of using a supplement like Manuka bean, it seems
William321
in
Cure Parkinson's
4 years ago
Final verdict on the efficacy of Nilotinib by the two trials: Georgetown University and Michael J Fox Foundation (MJFF)
To all those interested in Nilotinib the 2 Nilotinib trials, one at Georgetown University and the other a MJFF sponsored trial involving 25 research centres. On December 17 MJFF held a special webinar (https://www.michaeljfox.org/webinar/results-context-nilotinib-parkinsons-disease-nilo-pd) where the
To all those interested in Nilotinib the 2 Nilotinib trials, one at Georgetown University and the other a MJFF sponsored trial involving 25 research centres. On December 17 MJFF held a special webinar (https://www.michaeljfox.org/webinar/results-context-nilotinib-parkinsons-disease-nilo-pd) where the
Dogmatic377
in
Cure Parkinson's
4 years ago
Need help please, sense of smell, response to C/l, and sleep issue POLL
I’m confused. I’ve been clinically diagnosed with Parkinson’s with a DatScan performed in Dec. 2018. 4 months prior to my DatScan raised my antidepressant to max levels from the lowest level I had been taking for about 6 years prior. My symptoms got worse overnight. Looking back, my symptoms started
I’m confused. I’ve been clinically diagnosed with Parkinson’s with a DatScan performed in Dec. 2018. 4 months prior to my DatScan raised my antidepressant to max levels from the lowest level I had been taking for about 6 years prior. My symptoms got worse overnight. Looking back, my symptoms started
38yroldmale
in
Cure Parkinson's
4 years ago
PD & parkinsonism: vascular dementia
cluster=8370823593099015494&hl=en&as_sdt=0,6&sciodt=0,6
Parkinsonism
: PD: Vascular contributions to cognitive impairment and dementia. https://scholar.google.com/scholar?
cluster=8370823593099015494&hl=en&as_sdt=0,6&sciodt=0,6
Parkinsonism
: PD: Vascular contributions to cognitive impairment and dementia. https://scholar.google.com/scholar?
aspergerian
in
Cure Parkinson's
5 years ago
MEDICAL MARIJUANA EXPERT ADVISE REQUIRED!
DO'S AND DONT'S PRESCRIBED DRUG INTERACTION CAUTIONS HOW IT OXIDIZES AND REMOVED FROM THE BODY CYP3A4 ENZYME EFFECT? SAFE TO BE USED WITH MAO INHIBITORS? ALONG WITH 5-HTP? Even the people working at the dispensaries know the answer to these questions....are you?
DO'S AND DONT'S PRESCRIBED DRUG INTERACTION CAUTIONS HOW IT OXIDIZES AND REMOVED FROM THE BODY CYP3A4 ENZYME EFFECT? SAFE TO BE USED WITH MAO INHIBITORS? ALONG WITH 5-HTP? Even the people working at the dispensaries know the answer to these questions....are you?
marnegro
in
Cure Parkinson's
4 years ago
New ray of hope for people living with Parkinson’s disease
https://www.thehealthsite.com/news/new-ray-of-hope-for-people-living-with-parkinsons-disease-723790/ Parkinson's disease affects millions across the world. A non-invasive technique may soon come to the rescue. A non-invasive technique which could be used later to treat Parkinson’s disease has been discovered
https://www.thehealthsite.com/news/new-ray-of-hope-for-people-living-with-parkinsons-disease-723790/ Parkinson's disease affects millions across the world. A non-invasive technique may soon come to the rescue. A non-invasive technique which could be used later to treat Parkinson’s disease has been discovered
John_morris71
in
Cure Parkinson's
4 years ago
New study could 'drastically' change how we understand Parkinson's
The research, which appears in the journal Current Biology, found that symptoms of Parkinson's disease appear before the premature death of dopaminergic neurons. "However, this research demonstrates that functional inhibition of dopaminergic neurons by surrounding astrocytes is the core cause of [Parkinon's
The research, which appears in the journal Current Biology, found that symptoms of Parkinson's disease appear before the premature death of dopaminergic neurons. "However, this research demonstrates that functional inhibition of dopaminergic neurons by surrounding astrocytes is the core cause of [Parkinon's
Kia17
in
Cure Parkinson's
4 years ago
Hi everyone. Happy to be here
Hi all. I am just joining the group. And I have just ordered my first mannitol and Zandopa from Amazon. I was diagnosed with PD in late Nov and quickly deteriorated with multiple symptoms to a point where I could not get up from a chair. I improved a lot since then by doing glutten/sugar free diet and
Hi all. I am just joining the group. And I have just ordered my first mannitol and Zandopa from Amazon. I was diagnosed with PD in late Nov and quickly deteriorated with multiple symptoms to a point where I could not get up from a chair. I improved a lot since then by doing glutten/sugar free diet and
JudithKenya
in
Cure Parkinson's
4 years ago
Exenatide Once Weekly Over 2 Years as a Potential Disease Modifying Treatment for Parkinson's Disease (Exenatide-PD3)
Newly launched clinical trial https://clinicaltrials.gov/ct2/show/NCT04232969
Newly launched clinical trial https://clinicaltrials.gov/ct2/show/NCT04232969
Farooqji
in
Cure Parkinson's
4 years ago
Gastric emptying Pancreatic Polypeptide in PD: Parasympathetic Denervatio?
Pancreatic Polypeptide in Parkinson's Disease: A Potential Marker of Parasympathetic Denervation. https://www.ncbi.nlm.nih.gov/m/pubmed/28922171/
Pancreatic Polypeptide in Parkinson's Disease: A Potential Marker of Parasympathetic Denervation. https://www.ncbi.nlm.nih.gov/m/pubmed/28922171/
aspergerian
in
Cure Parkinson's
5 years ago
Specific gut bacteria may reduce severity of Parkinson's disease
Hi Everyone, I am unable to attach the articles, but please check out the latest research on the probiotic Bacillus subtilis. The study published in the journal, Cell Reports, describe how a particular probiotic bacterium may have the ability to prevent the abnormal accumulation of the alpha-synuclein
Hi Everyone, I am unable to attach the articles, but please check out the latest research on the probiotic Bacillus subtilis. The study published in the journal, Cell Reports, describe how a particular probiotic bacterium may have the ability to prevent the abnormal accumulation of the alpha-synuclein
Poss
in
Cure Parkinson's
5 years ago
Ambroxol in Parkinson's: Results of Phase ll Trial Published
Today The Cure Parkinson's Trust, in partnership with the Van Andel Institute and the John Black Charitable Foundation, announced the publication of the results of a Phase II clinical trial that evaluated the safety and tolerability of a drug called ambroxol to treat Parkinson's. The results of the AiM-PD
Today The Cure Parkinson's Trust, in partnership with the Van Andel Institute and the John Black Charitable Foundation, announced the publication of the results of a Phase II clinical trial that evaluated the safety and tolerability of a drug called ambroxol to treat Parkinson's. The results of the AiM-PD
Farooqji
in
Cure Parkinson's
5 years ago
Basic dopamine question
I'm hoping one ye clever cats can help me understand something. Dopamine is made in the following way: Phenylalanine -> tyrosine -> l-dopa -> dopamine Who is responsible for doing this? Is it the dopamine neuron job or is it just the neuron's job to deliver the dopamine across the brain once it's produced
I'm hoping one ye clever cats can help me understand something. Dopamine is made in the following way: Phenylalanine -> tyrosine -> l-dopa -> dopamine Who is responsible for doing this? Is it the dopamine neuron job or is it just the neuron's job to deliver the dopamine across the brain once it's produced
Parkinsonjisung
in
Cure Parkinson's
5 years ago
Red flags suggesting atypical parkinsonism disorders + treatment for these disorders (incl PSP, CBD)
See: https://www.brainsupportnetwork.org/red-flags-suggesting-an-atypical-
parkinsonism
-disorder-and-treatment-of-dlb-msa-psp-and-cbd/ RobinR
See: https://www.brainsupportnetwork.org/red-flags-suggesting-an-atypical-
parkinsonism
-disorder-and-treatment-of-dlb-msa-psp-and-cbd/ RobinR
rriddle
in
PSP Association
5 years ago
Awakening Dormant Neurons Could Provide Disease-modifying Parkinson’s Treatment, Early Study Suggests
Here's the same subject matter in the article with less technical terms. Awakening Dormant Neurons Could Provide Disease-modifying Parkinson’s Treatment, Early Study Suggests https://parkinsonsnewstoday.com/2020/01/13/awakening-dormant-neurons-could-provide-disease-modifying-parkinsons-treatment-animal-study
Here's the same subject matter in the article with less technical terms. Awakening Dormant Neurons Could Provide Disease-modifying Parkinson’s Treatment, Early Study Suggests https://parkinsonsnewstoday.com/2020/01/13/awakening-dormant-neurons-could-provide-disease-modifying-parkinsons-treatment-animal-study
pvw2
in
Cure Parkinson's
5 years ago
A simple test to detect self-evident clusters
I first posted this on the Neurotalk/Parkinson's forum 5 years ago. I think it is worth discussing here. This post tries to help answer questions like: In a town of 10,000 people, 50 are diagnosed with PD. Is this obviously a cluster? Four people in my football (soccer) team have gone on to develop
I first posted this on the Neurotalk/Parkinson's forum 5 years ago. I think it is worth discussing here. This post tries to help answer questions like: In a town of 10,000 people, 50 are diagnosed with PD. Is this obviously a cluster? Four people in my football (soccer) team have gone on to develop
johntPM
in
Cure Parkinson's
5 years ago
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