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Nubeqa
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Darolutamide & time to treatment discontinuation in nmCRPC
Further to the recent Apalutamide thred, we now have [1]: "A real-world analysis of the androgen receptor inhibitors (ARIs) darolutamide (
Nubeqa
), enzalutamide (Xtandi), and apalutamide (Erleada) found that darolutamide had a longer time to treatment discontinuation and longer time to progression to
Further to the recent Apalutamide thred, we now have [1]: "A real-world analysis of the androgen receptor inhibitors (ARIs) darolutamide (
Nubeqa
), enzalutamide (Xtandi), and apalutamide (Erleada) found that darolutamide had a longer time to treatment discontinuation and longer time to progression to
pca2004
in
Fight Prostate Cancer
1 year ago
Anyone on Nubeqa ? on triplicate therapy, Firmagon, Zytiga & Prednisone Started Docetaxel Chemotherapy no mention of Nubeqa DX 07/2022
If my husband’s switches from zytiga to
Nubeqa
can he now that he is going for his 3rd Docetaxel infusion… Dx 07/06/2022 read bio it’s all there Glease 8 Stage 4 PSA 942.40 09/13/2022 0.31
If my husband’s switches from zytiga to
Nubeqa
can he now that he is going for his 3rd Docetaxel infusion… Dx 07/06/2022 read bio it’s all there Glease 8 Stage 4 PSA 942.40 09/13/2022 0.31
Shorehousejam
in
Advanced Prostate Cancer
2 years ago
Low PSA, high metastasis, ready for chemo+
I was with another doc until last week who advised Eligard, plus
Nubeqa
and then Taxotere…the standard “triple therapy”but I didn’t feel he was throwing the proverbial kitchen sink at my disease which I think is warranted.
I was with another doc until last week who advised Eligard, plus
Nubeqa
and then Taxotere…the standard “triple therapy”but I didn’t feel he was throwing the proverbial kitchen sink at my disease which I think is warranted.
Skifanatic
in
Advanced Prostate Cancer
2 years ago
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Enzalutamide or Darolutamide
Hi, I have advanced metastatic hormone sensitive prostate cancer and as well as my usual three monthly ADT (Lucrin-Depot) injection, I have been offered either Enzalutamide (Xtandi) or Darolutamide (
Nubeqa
). My PSA is currently below 0.1 due to the Lucrin-Depot.
Hi, I have advanced metastatic hormone sensitive prostate cancer and as well as my usual three monthly ADT (Lucrin-Depot) injection, I have been offered either Enzalutamide (Xtandi) or Darolutamide (
Nubeqa
). My PSA is currently below 0.1 due to the Lucrin-Depot.
x-rays1
in
Advanced Prostate Cancer
1 year ago
A critical review of Provenge. Your inputs welcomed?
Maybe it's better to just start
Nubeqa
and skip the provenge? Any opinions or hard data/facts are welcome. George DOI: 10.1093/jnci/djr514 © The Author(s) 2012. Published by Oxford University Press. Advance Access publication on January 9, 2012.
Maybe it's better to just start
Nubeqa
and skip the provenge? Any opinions or hard data/facts are welcome. George DOI: 10.1093/jnci/djr514 © The Author(s) 2012. Published by Oxford University Press. Advance Access publication on January 9, 2012.
GeorgeGlass
in
Advanced Prostate Cancer
2 years ago
Sacrum tumor
Orch and
Nubeqa
, dx last year with advanced PC and bone mets.
Orch and
Nubeqa
, dx last year with advanced PC and bone mets.
Pops78
in
Advanced Prostate Cancer
2 years ago
Husband dx 07/01/22, Firmagon 07/06/22 Zytiga w/ Pred 07/20/22 Has anyone had Nubeqa prescriped during doxcetaxel, MO has not mentioned it
Husband currently doing docetaxel had second infusion on 09/13/22 Also suffers from psoriasis
Nubeqa
has been shown to be an effective therapy August 5, 2022, the Food and Drug Administration approved darolutamide (
Nubeqa
, Bayer HealthCare Pharmaceuticals Inc.) tablets in combination with docetaxel
Husband currently doing docetaxel had second infusion on 09/13/22 Also suffers from psoriasis
Nubeqa
has been shown to be an effective therapy August 5, 2022, the Food and Drug Administration approved darolutamide (
Nubeqa
, Bayer HealthCare Pharmaceuticals Inc.) tablets in combination with docetaxel
Shorehousejam
in
Advanced Prostate Cancer
2 years ago
Oral Hygiene and Zometa, Nubeqa, etc.
At this point after one month on
Nubeqa
and one Zometa infusion, I have no nausea or any oral issues. I was wondering if anyone else on Zometa,
Nubeqa
, Enzalutamide, etc. is taking these types of medicines for oral hygiene or gastrointestinal issues. Are they recommended as prevention? Thanks.
At this point after one month on
Nubeqa
and one Zometa infusion, I have no nausea or any oral issues. I was wondering if anyone else on Zometa,
Nubeqa
, Enzalutamide, etc. is taking these types of medicines for oral hygiene or gastrointestinal issues. Are they recommended as prevention? Thanks.
Silentio
in
Advanced Prostate Cancer
2 years ago
Newly diagnosed Stage IV Metastatic Prostate Cancer
My doctor put me on Lupron and Darolutimide (
Nubeqa
). My PSA has dropped to <.01. I feel great and I am in excellent shape for 75 years old. However, my Urologist Oncologist says the Darolutamide (
Nubeqa
) will stop working in 12-36 months. He offers no hope for me after that!
My doctor put me on Lupron and Darolutimide (
Nubeqa
). My PSA has dropped to <.01. I feel great and I am in excellent shape for 75 years old. However, my Urologist Oncologist says the Darolutamide (
Nubeqa
) will stop working in 12-36 months. He offers no hope for me after that!
sdmike2022
in
Advanced Prostate Cancer
2 years ago
Certain Toxic Effects Higher With Newer PCa Therapies— Reviews suggests increased risks of cognitive adverse events, fatigue, falls
[/i] [i]Currently, there are four second-generation AAs approved by the FDA for metastatic hormone-sensitive prostate cancer: abiraterone (Zytiga), enzalutamide (Xtandi), apalutamide (Erleada), and darolutamide (
Nubeqa
).
[/i] [i]Currently, there are four second-generation AAs approved by the FDA for metastatic hormone-sensitive prostate cancer: abiraterone (Zytiga), enzalutamide (Xtandi), apalutamide (Erleada), and darolutamide (
Nubeqa
).
cujoe
in
Fight Prostate Cancer
1 year ago
missed the boat on triplet therapy?
My question is would there be any benefit of adding one of agents (zytiga, xtandi,
nubeqa
) at this point or would we not really obtain the summative effects/should we just at this point wait for a progression since he isnt treatment naive anymore? tia
My question is would there be any benefit of adding one of agents (zytiga, xtandi,
nubeqa
) at this point or would we not really obtain the summative effects/should we just at this point wait for a progression since he isnt treatment naive anymore? tia
Idyllwild
in
Advanced Prostate Cancer
2 years ago
Any ideas on blood labs to monitor for earlier detection than PSA for becoming Castrate Resistant?
I am trying to get an idea of better test labs markers besides just the usual PSA for becoming castrat resistant, because if my SOC of ADT (Orgovyx, and
Nubeqa
) is starting to fail I would want to immediately jump on BAT. My doc always adds LDH.
I am trying to get an idea of better test labs markers besides just the usual PSA for becoming castrat resistant, because if my SOC of ADT (Orgovyx, and
Nubeqa
) is starting to fail I would want to immediately jump on BAT. My doc always adds LDH.
KocoPr
in
Advanced Prostate Cancer
2 years ago
When is enzalutamide going generic? DAROLUTAMIDE?
Nubeqa
aka Darolutamide will be eligible for patent challenges on July 30, 2023. This date may extended up to six months if a pediatric exclusivity extension is applied to the drug's patents. this is very good news!!
Nubeqa
aka Darolutamide will be eligible for patent challenges on July 30, 2023. This date may extended up to six months if a pediatric exclusivity extension is applied to the drug's patents. this is very good news!!
Scout4answers
in
Advanced Prostate Cancer
2 years ago
Can darolutamide be prescribed to metastatic, castrate-resistant PC
Has anyone been prescribed darolutamide (
NUBEQA
) once you had metastatic, castrate-resistant PC? My oncologist at Dana-Farber wants to prescribe darolutamide to me but the insurance company has denied it because they are claiming it is not for metastatic PC.
Has anyone been prescribed darolutamide (
NUBEQA
) once you had metastatic, castrate-resistant PC? My oncologist at Dana-Farber wants to prescribe darolutamide to me but the insurance company has denied it because they are claiming it is not for metastatic PC.
Eddy-Merckx
in
Advanced Prostate Cancer
2 years ago
Which statin to take with Nubeqa/Darolutamide? Pitivastatin or a different statin?
This post/question has more to do with taking it with
Nubeqa
, and not just a specific assessment of statins. Crestor has been good to me for six years, but it's listed as moderate interaction with
Nubeqa
.
This post/question has more to do with taking it with
Nubeqa
, and not just a specific assessment of statins. Crestor has been good to me for six years, but it's listed as moderate interaction with
Nubeqa
.
GeorgeGlass
in
Advanced Prostate Cancer
2 years ago
Rising PSA
Started on 3 Firmagon shots and was switched to Lupron and he's taking Darolutimide (
Nubeqa
) and has had 2 Docetaxel treatments so far. PSA started out at 57.7 and went down to 1.27 on 9/20. His most recent blood work on 10/11 his PSA rose to 7.96.
Started on 3 Firmagon shots and was switched to Lupron and he's taking Darolutimide (
Nubeqa
) and has had 2 Docetaxel treatments so far. PSA started out at 57.7 and went down to 1.27 on 9/20. His most recent blood work on 10/11 his PSA rose to 7.96.
Izzygirl1
in
Advanced Prostate Cancer
2 years ago
Can eat a grassfed beef liver while in the process of Docetaxel chemo?
86-year-old advanced prostate dx in 2018, Tried Zytiga, EBRT, Xtandi, Elreda and
Nubeqa
. Started Docetaxel chemo last July 12/22 and 2nd time is in progress. His blood works is relatively low but within the limit. Can he eat the liver? Thank you.
86-year-old advanced prostate dx in 2018, Tried Zytiga, EBRT, Xtandi, Elreda and
Nubeqa
. Started Docetaxel chemo last July 12/22 and 2nd time is in progress. His blood works is relatively low but within the limit. Can he eat the liver? Thank you.
11redtomato_41
in
Advanced Prostate Cancer
2 years ago
Jevtana stopped working. Considering Nubeqa
Oncologist ordered a bone scan and we discussed
Nubeqa
. scan indicated multiple mets in spin and ribs and old mets active. I'll see oncologist soon and sure he'll order PMSA scan. Anyone used
Nubeqa
in circumstances such as this? Any other thoughts or recommendations? Thank You.
Oncologist ordered a bone scan and we discussed
Nubeqa
. scan indicated multiple mets in spin and ribs and old mets active. I'll see oncologist soon and sure he'll order PMSA scan. Anyone used
Nubeqa
in circumstances such as this? Any other thoughts or recommendations? Thank You.
Altamontt
in
Advanced Prostate Cancer
2 years ago
Xtandi vs. Abiraterone vs. Nubeqa
My current insurance doesn’t include Xtandi in the formulary - abiraterone &
Nubeqa
are the covered options. An appeal is underway and coverage seems likely. But looking ahead to January when I transition to Medicare, Xtandi would cost about $12k/ yr.
My current insurance doesn’t include Xtandi in the formulary - abiraterone &
Nubeqa
are the covered options. An appeal is underway and coverage seems likely. But looking ahead to January when I transition to Medicare, Xtandi would cost about $12k/ yr.
shueswim
in
Advanced Prostate Cancer
2 years ago
Found his maxillary Osteonecrosis of the jaw has exposed and his 4th chemo. of Docetaxel is due in a few days. Chemo making worse to ONJ?
Used zytiga, xtandi, erlida, and
nubeqa
and all developed resistant and started Chemo, Docetaxel last July and continue Lupron and Xgeva.Any advice is really appreciated. Thank you immensely.
Used zytiga, xtandi, erlida, and
nubeqa
and all developed resistant and started Chemo, Docetaxel last July and continue Lupron and Xgeva.Any advice is really appreciated. Thank you immensely.
11redtomato_41
in
Advanced Prostate Cancer
2 years ago
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