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BLA for Subcutaneous Nivolumab Accepted by the FDA for Advanced/Metastatic Solid Tumors
A biologics license application (BLA) has been accepted by the FDA seeking approval of nivolumab (Opdivo) co-formulated with Halozyme’s proprietary recombinant human hyaluronidase (rHuPH20; subcutaneous nivolumab) for adult patients with solid tumors eligible for previously approved nivolumab indications
A biologics license application (BLA) has been accepted by the FDA seeking approval of nivolumab (Opdivo) co-formulated with Halozyme’s proprietary recombinant human hyaluronidase (rHuPH20; subcutaneous nivolumab) for adult patients with solid tumors eligible for previously approved nivolumab indications
God_Loves_Me
in
Advanced Prostate Cancer
2 days ago
Thank you Angela for sharing your story!
“I have never really been a sun worshipper but I have used sunbeds in the past. I used to hire one for use at home in my late teens/early 20’s then used the stand-up ones on and off at tanning salons a few years after that. I never thought there was any harm in using sunbeds and I can’t remember seeing
“I have never really been a sun worshipper but I have used sunbeds in the past. I used to hire one for use at home in my late teens/early 20’s then used the stand-up ones on and off at tanning salons a few years after that. I never thought there was any harm in using sunbeds and I can’t remember seeing
SkcinHQ
Partner
in
Skin Cancer UK
3 days ago
Side effects on combination therapy : thyroxine and T3
I have been on combination therapy for about 7 weeks. I have noticed I am quite breathless and this looks like it can be related but unusual. Does this sound familiar to anyone?
I have been on combination therapy for about 7 weeks. I have noticed I am quite breathless and this looks like it can be related but unusual. Does this sound familiar to anyone?
TheaW
in
Thyroid UK
4 days ago
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Targeting the glutamine metabolism to suppress cell proliferation in mesenchymal docetaxel-resistant prostate cancer
Source Link : https://www.nature.com/articles/s41388-024-03059-4 Docetaxel (DX) serves as a palliative treatment option for metastatic prostate cancer (PCa). Despite initial remission, acquired DX resistance is inevitable. The mechanisms behind DX resistance have not yet been deciphered, but a mesenchymal
Source Link : https://www.nature.com/articles/s41388-024-03059-4 Docetaxel (DX) serves as a palliative treatment option for metastatic prostate cancer (PCa). Despite initial remission, acquired DX resistance is inevitable. The mechanisms behind DX resistance have not yet been deciphered, but a mesenchymal
God_Loves_Me
in
Advanced Prostate Cancer
4 days ago
constipation leading to Pelvic Floor dysfunction
I have IBS - C and over the years the medical fraternity have prescribed laxatives for me. I’m following a low fermentation & FODMAP diet which works well for me. However my constipation due to a lot of straining has turned into PFD which basically means my anal muscles are out of sync. Does anyone suffer
I have IBS - C and over the years the medical fraternity have prescribed laxatives for me. I’m following a low fermentation & FODMAP diet which works well for me. However my constipation due to a lot of straining has turned into PFD which basically means my anal muscles are out of sync. Does anyone suffer
Profound15
in
IBS Network
5 days ago
Enemas for constipation
I am taking flecainide and bisoprolol for my afib. The medication is doing fine but I’ve got what I believe to be Pelvic Floor dysfunction. Basically one of my rectum muscles (at exit) is contracting when it should be relaxing. I’ve got biofeedback physio on Monday but wanted to know if anyone has experience
I am taking flecainide and bisoprolol for my afib. The medication is doing fine but I’ve got what I believe to be Pelvic Floor dysfunction. Basically one of my rectum muscles (at exit) is contracting when it should be relaxing. I’ve got biofeedback physio on Monday but wanted to know if anyone has experience
Profound15
in
Atrial Fibrillation Support
5 days ago
Interesting new targeted therapy trial
I like this company’s mission. They have a Phase 1/2 trial underway at Mass General in Boston with a new miRNA-10b treatment. https://www.transcodetherapeutics.com TransCode’s lead therapeutic candidate, TTX-MC138, is a targeted therapy designed to treat cancer patients with metastatic cancer,
I like this company’s mission. They have a Phase 1/2 trial underway at Mass General in Boston with a new miRNA-10b treatment. https://www.transcodetherapeutics.com TransCode’s lead therapeutic candidate, TTX-MC138, is a targeted therapy designed to treat cancer patients with metastatic cancer,
Best521
in
SHARE Metastatic Breast Cancer
6 days ago
InkMune clinical trial goes on: second cohort is being treated
In phase 1/2 CaRe PC trial (NCT06056791) evaluating INKmune, a biologic therapy In its announcement on Monday, INmune said it successfully completed nine INKmune administrations in the outpatient setting within the first cohort in the trial. None of the patients who have received INKmune so far have
In phase 1/2 CaRe PC trial (NCT06056791) evaluating INKmune, a biologic therapy In its announcement on Monday, INmune said it successfully completed nine INKmune administrations in the outpatient setting within the first cohort in the trial. None of the patients who have received INKmune so far have
Maxone73
in
Advanced Prostate Cancer
8 days ago
Holistic POSITIVE results
Hello, I was dx with PD in 2019. I’ve progressed to stage 3 and have tried a lot of synthetic meds. I wont take tgem if the side effects worsen my current symptoms. That excludes most. I have read a million articles on new and upcoming tests and trials. I’m tired of chasing the rabbit. Although I cant
Hello, I was dx with PD in 2019. I’ve progressed to stage 3 and have tried a lot of synthetic meds. I wont take tgem if the side effects worsen my current symptoms. That excludes most. I have read a million articles on new and upcoming tests and trials. I’m tired of chasing the rabbit. Although I cant
GigiOf8
in
Cure Parkinson's
8 days ago
Obstructed Defaecation Syndrome
Hi everyone, Does any of you have Obstructed Defaecation Syndrome caused by Dyssynergic Defecation? I have been referred to biofeedback therapy that I will start on the 21st of May. I hope it will be helpful for me.
Hi everyone, Does any of you have Obstructed Defaecation Syndrome caused by Dyssynergic Defecation? I have been referred to biofeedback therapy that I will start on the 21st of May. I hope it will be helpful for me.
EnikoF
in
IBS Network
11 days ago
What Kidney Patients Need to Know About Medical Nutrition Therapy
Medical Nutrition Therapy (MNT) is an evidence-based medical approach to treating certain chronic conditions through the use of an individually tailored nutrition plan based on a comprehensive nutrition assessment conducted by a Registered Dietitian (RD). Tell Congress to support the Medical Nutrition
Medical Nutrition Therapy (MNT) is an evidence-based medical approach to treating certain chronic conditions through the use of an individually tailored nutrition plan based on a comprehensive nutrition assessment conducted by a Registered Dietitian (RD). Tell Congress to support the Medical Nutrition
JackieJ_NKF
Partner
in
Kidney Dialysis
12 days ago
Vocal chord damage in thyroidectomy
Hi all, I had a total Thyroidectomy 2 days ago which was a difficult op. My thyroid had grown so large it was pressing on my larynx, growing downwards to my chest, and growing round the back of my oesophagus. In previous surgery for breast cancer 2 years ago they were unable to get the breathing tube
Hi all, I had a total Thyroidectomy 2 days ago which was a difficult op. My thyroid had grown so large it was pressing on my larynx, growing downwards to my chest, and growing round the back of my oesophagus. In previous surgery for breast cancer 2 years ago they were unable to get the breathing tube
Peppermint20
in
Thyroid UK
12 days ago
Gene therapy
I know it's not PD but it is a neurological condition and sounds like a hopeful developmentUK toddler has hearing restored in world first gene therapy trial https://www.theguardian.com/science/article/2024/may/09/uk-toddler-has-hearing-restored-in-world-first-gene-therapy-trial?CMP=share_btn_url
I know it's not PD but it is a neurological condition and sounds like a hopeful developmentUK toddler has hearing restored in world first gene therapy trial https://www.theguardian.com/science/article/2024/may/09/uk-toddler-has-hearing-restored-in-world-first-gene-therapy-trial?CMP=share_btn_url
WinnieThePoo
in
Cure Parkinson's
12 days ago
speech therapist questions
my mum will be visiting a speech therapist tomorrow, what are the areas you suggest the speech therapist should focus on? What questions do you think will be helpful?
my mum will be visiting a speech therapist tomorrow, what are the areas you suggest the speech therapist should focus on? What questions do you think will be helpful?
Candor8
in
PSP Association
14 days ago
Webinar: Exploring Valeda light therapy for AMD
We will be delving into the science behind Valeda light therapy for treating age-related macular degeneration (AMD). In this session, we’ll be joined Professor Tim Jackson, consultant ophthalmic surgeon from King’s College Hospital, to explore the science behind the Valeda photobiomodulation technique
We will be delving into the science behind Valeda light therapy for treating age-related macular degeneration (AMD). In this session, we’ll be joined Professor Tim Jackson, consultant ophthalmic surgeon from King’s College Hospital, to explore the science behind the Valeda photobiomodulation technique
Carol_MacularSociety
Partner
in
Macular Society
14 days ago
red light therapy
Hi I have been looking into the benefits of red light therapy for muscle issues and wondered if anyone had tried this - I can’t see any contradictions with hydroxi and will be mainly using this on my neck , upper back and thyroid areas - I know this won’t help ET as such but using for other issues.
Hi I have been looking into the benefits of red light therapy for muscle issues and wondered if anyone had tried this - I can’t see any contradictions with hydroxi and will be mainly using this on my neck , upper back and thyroid areas - I know this won’t help ET as such but using for other issues.
BeckyDing
in
MPN Voice
14 days ago
Severe intrusive thoughts
Hello I have a family member that is in dire need of help. They have recently become homeless and have tried many different treatments and medications for their severe OCD which presents in rituals and severe intrusive thoughts and mood swings. I am at a loss on how to help this relative. No one takes
Hello I have a family member that is in dire need of help. They have recently become homeless and have tried many different treatments and medications for their severe OCD which presents in rituals and severe intrusive thoughts and mood swings. I am at a loss on how to help this relative. No one takes
Seekingocdhelp
in
My OCD Community
16 days ago
#AskChatGPT : list of immunotherapy drugs for prostate cancer
As of my last update in January 2022, several immunotherapy drugs have been studied or are currently being investigated for the treatment of prostate cancer. Here are some of the notable ones: Sipuleucel-T (Provenge): Sipuleucel-T is an autologous cellular immunotherapy approved for the treatment
As of my last update in January 2022, several immunotherapy drugs have been studied or are currently being investigated for the treatment of prostate cancer. Here are some of the notable ones: Sipuleucel-T (Provenge): Sipuleucel-T is an autologous cellular immunotherapy approved for the treatment
God_Loves_Me
in
Advanced Prostate Cancer
19 days ago
Oxygen therapy
I have been referred for this and told I would get a visit at home. Just had first chest infection and inpatient stay, 3 days. Antibiotics worked super well, plus excellent ambulance crew. What is involved with oxygen at home, is it a small mobile cylinder? Do I take it everywhere. How does it work
I have been referred for this and told I would get a visit at home. Just had first chest infection and inpatient stay, 3 days. Antibiotics worked super well, plus excellent ambulance crew. What is involved with oxygen at home, is it a small mobile cylinder? Do I take it everywhere. How does it work
grahame151
in
Lung Conditions Community Forum
19 days ago
Recently diagnosed and trying to work out what to do! All advice gratefully received.
I was diagnosed this week. Still in shock a bit as I am a fit and very active 58 with no real symptoms. I have a psa of 7.7. Gleason Score 3+4 = 7 one in 10 cores with a 2.5mm tumour length whoich is 20% of the core involved. 30% of cores showed cribreform pattern 4 glands. Area of concern on MRIs
I was diagnosed this week. Still in shock a bit as I am a fit and very active 58 with no real symptoms. I have a psa of 7.7. Gleason Score 3+4 = 7 one in 10 cores with a 2.5mm tumour length whoich is 20% of the core involved. 30% of cores showed cribreform pattern 4 glands. Area of concern on MRIs
welshsky
in
Prostate Cancer Network
21 days ago
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