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Potential therapeutic effects and pharmacological evidence of sinomenine in central nervous system disorders
Published online 2022 Sep 16, I realize it is a rat study, but it is sinomenine is used in Traditional Chinese Medicine. Pharmacological effects of sinomenine in Parkinson’s disease PD is a common neurodegenerative disorder characterized by progressive degeneration of dopaminergic neurons in the
Published online 2022 Sep 16, I realize it is a rat study, but it is sinomenine is used in Traditional Chinese Medicine. Pharmacological effects of sinomenine in Parkinson’s disease PD is a common neurodegenerative disorder characterized by progressive degeneration of dopaminergic neurons in the
Sydney75
in
Cure Parkinson's
5 months ago
missed yall
I hope everyone is well or doing the best they can. I took a bit of a break just out doing my best 😊 Had an anxiety attack last night before bed but there were some circumstances that kinda led up to it that I let get the best of me. Plus I’ve missed a few doses of meds 🙄 I think that when I am
I hope everyone is well or doing the best they can. I took a bit of a break just out doing my best 😊 Had an anxiety attack last night before bed but there were some circumstances that kinda led up to it that I let get the best of me. Plus I’ve missed a few doses of meds 🙄 I think that when I am
Mskitty21
in
Anxiety and Depression Support
3 months ago
Light at end of tunnel?
Finally withdrawal done. No more depression meds. Lost 10 lbs and head clearer. Still dealing with cheating spouse. Closing on new home in another state..with him. Only thing good about it is will be so much closer to my family. Still suffer from panic attacks but thankfully few and far between. I
Finally withdrawal done. No more depression meds. Lost 10 lbs and head clearer. Still dealing with cheating spouse. Closing on new home in another state..with him. Only thing good about it is will be so much closer to my family. Still suffer from panic attacks but thankfully few and far between. I
Hidden
in
Anxiety and Depression Support
7 months ago
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anxiety depression
hi everyone I am struggling with chronic anxiety attacks and mild depression. Anxiety to a point where I’m scared of being left alone at home
hi everyone I am struggling with chronic anxiety attacks and mild depression. Anxiety to a point where I’m scared of being left alone at home
Niecy89
in
Anxiety and Depression Support
4 months ago
Serum ferritin level & RBC count help please
Hi there, just wondered If anyone could please tell me if a Ferritin level of 44ng/ml and a RBC count of 3.76 (whilst actually already taking Ferrous Fumerate 210mg twice per day) is still pretty low and ‘could’ maybe be the reason I’m still feeling exhausted/heavy tired legs?? Thank you in advance
Hi there, just wondered If anyone could please tell me if a Ferritin level of 44ng/ml and a RBC count of 3.76 (whilst actually already taking Ferrous Fumerate 210mg twice per day) is still pretty low and ‘could’ maybe be the reason I’m still feeling exhausted/heavy tired legs?? Thank you in advance
CandiR
in
Pernicious Anaemia Society
6 months ago
Journaling failures and tips
I believe, and my neurologist and therapist have recommended, that I start journaling. This is something that I have wanted to do for decades and hoping, planning, and then failing again to start seems to create a daily source of frustration, guilt, and disappointment. If I could do one line a day that
I believe, and my neurologist and therapist have recommended, that I start journaling. This is something that I have wanted to do for decades and hoping, planning, and then failing again to start seems to create a daily source of frustration, guilt, and disappointment. If I could do one line a day that
Sunrisetabby
in
Anxiety and Depression Support
4 months ago
Losing track of where you are while driving
Have you ever lost track of where you are while driving? I've probably had this occur 3-4 times in the last year in places I have gone to many times. Twice this was when I was approaching a street where I had to turn. Suddenly I didn't know if I needed to keep going or turn, or had taken the wrong
Have you ever lost track of where you are while driving? I've probably had this occur 3-4 times in the last year in places I have gone to many times. Twice this was when I was approaching a street where I had to turn. Suddenly I didn't know if I needed to keep going or turn, or had taken the wrong
Doxy46
in
MPN Voice
6 months ago
Bolt's Failed Pickle Experiment (Lectins) :(
First off, for those who don't know me, I have NOT been diagnosed with PD
. I was diagnosed with REM Sleep Behavior Disorder back in April 21, which the experts say will lead to PD or something worse. When I was diagnosed I did have some other odd symptoms. Mild balance issues, Seborrheic dermatitis
First off, for those who don't know me, I have NOT been diagnosed with PD
. I was diagnosed with REM Sleep Behavior Disorder back in April 21, which the experts say will lead to PD or something worse. When I was diagnosed I did have some other odd symptoms. Mild balance issues, Seborrheic dermatitis
Bolt_Upright
in
Cure Parkinson's
6 months ago
Legal Advice?
Hi All, Although this post is not MS-related, I wanted to reach out to my MSAA Community for their input. Perhaps someone here can point me in the right direction, as I don't really have the money to hire an attorney. Unfortunately, this situation doesn't lend itself to any "free advice and/or attorneys
Hi All, Although this post is not MS-related, I wanted to reach out to my MSAA Community for their input. Perhaps someone here can point me in the right direction, as I don't really have the money to hire an attorney. Unfortunately, this situation doesn't lend itself to any "free advice and/or attorneys
DM0329
in
My MSAA Community
6 months ago
Frequent med changes
Looking for some advice as I am feeling lost and well just defeated that we are hitting another wall/falling off the cliff again med wise.My son is 8 with Adhd and anxiety/
mood
disorder
.
Looking for some advice as I am feeling lost and well just defeated that we are hitting another wall/falling off the cliff again med wise.My son is 8 with Adhd and anxiety/
mood
disorder
.
SurvivorFan
in
CHADD's ADHD Parents Together
5 months ago
I want to help if I can
I have be dx in1986 w/ RRMS, I had be misdiagnosed approximately 5 times, one of the Dr.s telling me to quit my job in a jail because I was a woman. Long story short I went completely paralyzed and in a rehab for approximately 6 weeks. I learned to walk, talk, adl, etc until my release when I went
I have be dx in1986 w/ RRMS, I had be misdiagnosed approximately 5 times, one of the Dr.s telling me to quit my job in a jail because I was a woman. Long story short I went completely paralyzed and in a rehab for approximately 6 weeks. I learned to walk, talk, adl, etc until my release when I went
BlondiePink
in
My MSAA Community
6 months ago
Ran out of Buserelin - FET
Hi, I was scheduled for my last Buserelin injection on Thursday ahead of FET next week (Thursday). I thought I had just enough left in the vial but there were only a few drops when I drew it up so I didn't get a full injection (or anything close) Initially I wasn't worried, my lining looked good at D9
Hi, I was scheduled for my last Buserelin injection on Thursday ahead of FET next week (Thursday). I thought I had just enough left in the vial but there were only a few drops when I drew it up so I didn't get a full injection (or anything close) Initially I wasn't worried, my lining looked good at D9
GreenOpera
in
Fertility Network UK
8 months ago
wrong possible diagnosis?
Has anyone that’s been diagnosed with cyclothmia also had an episode of psychosis with extreme mania? (Mine was delayed post partum psychosis at 10 months) I’m really confused. My mental health team said I’m too complex to give a final diagnosis yet, as I’ve had lots and lots of different mental health
Has anyone that’s been diagnosed with cyclothmia also had an episode of psychosis with extreme mania? (Mine was delayed post partum psychosis at 10 months) I’m really confused. My mental health team said I’m too complex to give a final diagnosis yet, as I’ve had lots and lots of different mental health
Isabella5991
in
Action on Postpartum Psychosis
8 months ago
(Very) Irregular Periods Post Recovery
Hello, I wanted to ask if anyone in this community experienced persistent menstrual dysfunction following recovery from anorexia? For some background, I had anorexia from ages 11 - 18. I reached the menarche (had my first period) at 17, following weight restoration. My eating patterns and BMI have
Hello, I wanted to ask if anyone in this community experienced persistent menstrual dysfunction following recovery from anorexia? For some background, I had anorexia from ages 11 - 18. I reached the menarche (had my first period) at 17, following weight restoration. My eating patterns and BMI have
Capybara571
in
Talk ED (eating disorders)
6 months ago
Depression
I have bipolar 1, anxiety and OCD. I have been in remission for about 15 years, but recently I have been experiencing feelings of depression and low self esteem. I have an excellent doctor and will be contacting him tomorrow. I would like to know what coping strategies others use when they feel that
I have bipolar 1, anxiety and OCD. I have been in remission for about 15 years, but recently I have been experiencing feelings of depression and low self esteem. I have an excellent doctor and will be contacting him tomorrow. I would like to know what coping strategies others use when they feel that
Grandmakris
in
Anxiety and Depression Support
8 months ago
Sertraline or SSRI with Olanzapine
Did anyone take Sertraline or another SSRI with Olanzapine. I have bad anxiety and am scared of Olanzapine because of a higher cardiac event risk. And then if you add Sertraline it can also cause adverse affects. So anxious about Olanzapine and then both.
Did anyone take Sertraline or another SSRI with Olanzapine. I have bad anxiety and am scared of Olanzapine because of a higher cardiac event risk. And then if you add Sertraline it can also cause adverse affects. So anxious about Olanzapine and then both.
lizziebennet
in
Action on Postpartum Psychosis
8 months ago
MSA or PSP - Parkinson's Plus
Hello,My brother is in mid 40s , diagnosed with Parkinson in 2020 after getting COVID-19. Since then, he has detoriated very rapidly. He has had MIBG scan recently which reveals he has PSP or MSA. We are very worried for him, at his age we weren't expecting this. Anyone in similar situation? What's the
Hello,My brother is in mid 40s , diagnosed with Parkinson in 2020 after getting COVID-19. Since then, he has detoriated very rapidly. He has had MIBG scan recently which reveals he has PSP or MSA. We are very worried for him, at his age we weren't expecting this. Anyone in similar situation? What's the
Sarah106
in
Cure Parkinson's
7 months ago
The Endotoxin Hypothesis of Parkinson's Disease
Abstract:
The endotoxin hypothesis of Parkinson's disease (PD) is the idea that lipopolysaccharide (LPS) endotoxins contribute to the pathogenesis of this disorder. LPS endotoxins are found in, and released from, the outer membrane of Gram-negative bacteria, for example in the gut. It is proposed
Abstract:
The endotoxin hypothesis of Parkinson's disease (PD) is the idea that lipopolysaccharide (LPS) endotoxins contribute to the pathogenesis of this disorder. LPS endotoxins are found in, and released from, the outer membrane of Gram-negative bacteria, for example in the gut. It is proposed
Bolt_Upright
in
Cure Parkinson's
6 months ago
I really need to vent
Do you ever just not want to bother anyone else? I do, I'd almost would rather suffer in silence. I've been suffering with depression, anxiety, and adhd. The last year has been the worst after a seperation from my ex fiance with 2 kids involved. I self isolate myself and try to ignore everything. I
Do you ever just not want to bother anyone else? I do, I'd almost would rather suffer in silence. I've been suffering with depression, anxiety, and adhd. The last year has been the worst after a seperation from my ex fiance with 2 kids involved. I self isolate myself and try to ignore everything. I
Joemamba13
in
Anxiety and Depression Support
4 months ago
Has anyone here gotten weight restored on their own without going to a nutritionist or eating disorder center?
I have anorexia nervosa and I have been to several treatment centers and seen several nutritionists in my life. They have never helped me as far as yes they help me gain the weight but then I don't end up getting my mind changed any even with all the psychotherapy so it ends up doing me no good. What
I have anorexia nervosa and I have been to several treatment centers and seen several nutritionists in my life. They have never helped me as far as yes they help me gain the weight but then I don't end up getting my mind changed any even with all the psychotherapy so it ends up doing me no good. What
Hidden
in
Talk ED (eating disorders)
6 months ago
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