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Alendronic acid quandary
After a recent DEXA scan I have found that I have osteopenia of the hips and some osteoporosis at L3 and L4. My doctor has put me on Alendronic acid tablets and 1200 mg calcium supplements(Adcal D3). After the first six days I had constipation and consequent haemorrhoids. I took the alendronic acid and
After a recent DEXA scan I have found that I have osteopenia of the hips and some osteoporosis at L3 and L4. My doctor has put me on Alendronic acid tablets and 1200 mg calcium supplements(Adcal D3). After the first six days I had constipation and consequent haemorrhoids. I took the alendronic acid and
Redtime
in
Bone Health and Osteoporosis UK
2 years ago
Update after consultant visit
Here is the update after consultant visit. As PMR pro suspected I have now been put on Alendronic acid, a liquid bottle of 70mg made up with 30mg water to 100mg weekly due to recent DEXA scan. She did say she didn't think my scan was bad as I am just past menopaused and many women are at this point without
Here is the update after consultant visit. As PMR pro suspected I have now been put on Alendronic acid, a liquid bottle of 70mg made up with 30mg water to 100mg weekly due to recent DEXA scan. She did say she didn't think my scan was bad as I am just past menopaused and many women are at this point without
Pawscat11
in
PMRGCAuk
2 years ago
Flare following Prolia?
Good morning, everyone! I wonder if anyone else has had problems following a denosumab (Prolia) injection. I was first diagnosed with PMR in 2015, and at that point, was told to discontinue the alendronic acid that I had been on for many years because it had been discovered it was not the “wonder drug
Good morning, everyone! I wonder if anyone else has had problems following a denosumab (Prolia) injection. I was first diagnosed with PMR in 2015, and at that point, was told to discontinue the alendronic acid that I had been on for many years because it had been discovered it was not the “wonder drug
Mrsd12f
in
PMRGCAuk
2 years ago
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Your thoughts/experience with zoledronic acid?
Good day, we had a consult with our urologist and he is prescribing zoldron for my dad because of metastasis, i have read some terrible side effects so i told our uro about that, to which he replied it probbly depends on the brand as some may have bad additives, also none of his patients reported any
Good day, we had a consult with our urologist and he is prescribing zoldron for my dad because of metastasis, i have read some terrible side effects so i told our uro about that, to which he replied it probbly depends on the brand as some may have bad additives, also none of his patients reported any
harleyharhar
in
Advanced Prostate Cancer
2 years ago
Starting IVF in 3 months with the NHS. Please share tips on how I can prep my body.
Hello Ladies, I am 28 and husband is 30 we are due to start our first IVF cyle in 3 months time with the NHS. So far it is deemed ‘unexplained’ as tests have come back fine. My AMH is 21.6 and I have been ttc for 2 years now. Never missed a period, have a regular cycles of 31 days. My CCG only offers
Hello Ladies, I am 28 and husband is 30 we are due to start our first IVF cyle in 3 months time with the NHS. So far it is deemed ‘unexplained’ as tests have come back fine. My AMH is 21.6 and I have been ttc for 2 years now. Never missed a period, have a regular cycles of 31 days. My CCG only offers
MissB22
in
Fertility Network UK
2 years ago
Bone Scan advice
Hello all, just a quick query . I've been on pred since the beginning of March , currently 12.5mg. I'm on Alendronic Acid too. I have been on Letrozole since my Mastectomy in June 2019. I had a bone scan then which is standard when starting something like Letrozole as it increases osteoporosis risk.
Hello all, just a quick query . I've been on pred since the beginning of March , currently 12.5mg. I'm on Alendronic Acid too. I have been on Letrozole since my Mastectomy in June 2019. I had a bone scan then which is standard when starting something like Letrozole as it increases osteoporosis risk.
Jigsawlass
in
PMRGCAuk
2 years ago
Alendronate/fosamax part 2
In 2014, after taking alendonate for (?) 5+ years, my left femur broke as I walked down a very slight slope. I have a intramedullary pin running from hip to knee. In 2020, on March 3, after not taking AA for nearly 6 years, I stood up to get off the bus, and my right femur broke, same reason. Now
In 2014, after taking alendonate for (?) 5+ years, my left femur broke as I walked down a very slight slope. I have a intramedullary pin running from hip to knee. In 2020, on March 3, after not taking AA for nearly 6 years, I stood up to get off the bus, and my right femur broke, same reason. Now
BrancepethCastle
in
Bone Health and Osteoporosis UK
2 years ago
Before You Book (or recommend) That Iron Infusion
Please read the article embedded in this post to FreeGaza. In my unprofessional opinion, if you feel you must have an infusion then ask for Iron Dextran. Dextrose is a single molecule sugar that theoretically should be able to cross the BBB. Injectafer and iron sucrose, in my humble opinion, don’t stand
Please read the article embedded in this post to FreeGaza. In my unprofessional opinion, if you feel you must have an infusion then ask for Iron Dextran. Dextrose is a single molecule sugar that theoretically should be able to cross the BBB. Injectafer and iron sucrose, in my humble opinion, don’t stand
Hidden
in
Restless Legs Syndrome
2 years ago
Meds help please
I’m on all the normal post bypass meds so those are sorted my questions is I’m on Adcal which is basically calcium for my bones I had cancer 11 years ago and now I don’t produce any testosterone which means I stand a high chance of osteoporosis I haven’t as yet but they give me adcal just in case.
I’m on all the normal post bypass meds so those are sorted my questions is I’m on Adcal which is basically calcium for my bones I had cancer 11 years ago and now I don’t produce any testosterone which means I stand a high chance of osteoporosis I haven’t as yet but they give me adcal just in case.
Jako999
in
British Heart Foundation
2 years ago
Hyaluronic acid treatment for damaged bladder
Hi guys finally getting some answers of what has been going on with my bladder. (Bleeding from it) Had a cystoscopy yesterday, after the usual embarrassing bits, I found it quite fascinating to see inside my bladder on the screen. She never gave me a diagnosis but looking at my past history it is probably
Hi guys finally getting some answers of what has been going on with my bladder. (Bleeding from it) Had a cystoscopy yesterday, after the usual embarrassing bits, I found it quite fascinating to see inside my bladder on the screen. She never gave me a diagnosis but looking at my past history it is probably
Dustyangel
in
Pelvic Radiation Disease Association
2 years ago
The Role Of Bile Acids In Prostate Cancer
Bile acids (BAs) belong to cholesterol-derived sterols. Due to the side chain carboxyl group and hydroxylation of their steroid ring they are more polar than cholesterol. They have an amphipatic character for which they are known as natural detergents. Majority of cholesterol is excreted by bile acids
Bile acids (BAs) belong to cholesterol-derived sterols. Due to the side chain carboxyl group and hydroxylation of their steroid ring they are more polar than cholesterol. They have an amphipatic character for which they are known as natural detergents. Majority of cholesterol is excreted by bile acids
Hidden
in
Advanced Prostate Cancer
2 years ago
Dexascan and Alendronate 70mg
After six years continuously on lupron, I had scan done on April 1st. I was DX with osteopenia. Doctor wants me too take alendronate 70mg once a week, I have some concerns about the side effects. Anyone taking this drug and what was your side effects. Thank ET51
After six years continuously on lupron, I had scan done on April 1st. I was DX with osteopenia. Doctor wants me too take alendronate 70mg once a week, I have some concerns about the side effects. Anyone taking this drug and what was your side effects. Thank ET51
Echotango51
in
Advanced Prostate Cancer
2 years ago
What is going on??
Help. Don’t know who to contact if anyone. Could be I’m a Jessie! On Wednesday of last week my left foot started swelling (I have Lupus, Sjogrens and fibromyalgia with costochondritis). Then the next day the other foot was a bit puffy. On that day I travelled from Wales to Bedfordshire and then from
Help. Don’t know who to contact if anyone. Could be I’m a Jessie! On Wednesday of last week my left foot started swelling (I have Lupus, Sjogrens and fibromyalgia with costochondritis). Then the next day the other foot was a bit puffy. On that day I travelled from Wales to Bedfordshire and then from
Bowenlady
in
LUPUS UK
2 years ago
PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy
Here is one out of far left field https://www.frontiersin.org/articles/10.3389/fphar.2021.692574/full PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy www.frontiersin.orgSi-Min Qi1†, www.frontiersin.orgJinyun Dong2†, www.frontiersin.orgZhi-Yuan Xu2, www.frontiersin.orgXiang-Dong
Here is one out of far left field https://www.frontiersin.org/articles/10.3389/fphar.2021.692574/full PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy www.frontiersin.orgSi-Min Qi1†, www.frontiersin.orgJinyun Dong2†, www.frontiersin.orgZhi-Yuan Xu2, www.frontiersin.orgXiang-Dong
Scout4answers
in
Advanced Prostate Cancer
2 years ago
Glycyrrhizin in licorice root is a novel pharmacological inhibition of HMGB1 that repress prostate cancer metastasis
High mobility group box 1 (HMGB1) is upregulated in nearly every tumor type. Importantly, clinical evidence also proposed that HMGB1 is particularly increased in metastatic prostate cancer patients. Besides, a growing number of studies highlighted that HMGB1 could be a successful therapeutic target for
High mobility group box 1 (HMGB1) is upregulated in nearly every tumor type. Importantly, clinical evidence also proposed that HMGB1 is particularly increased in metastatic prostate cancer patients. Besides, a growing number of studies highlighted that HMGB1 could be a successful therapeutic target for
Hidden
in
Advanced Prostate Cancer
2 years ago
Osteoporosis
Good morning, I’ve now received a diagnosis of osteoporosis in my hips and spine following a DEXA scan 6 weeks ago. I have GCA diagnosed in April 2021 and have been reducing prednisolone from 60mg to currently 6mg. My rheumatologist wants me to take alendronic acid which I’m worried about. I wonder if
Good morning, I’ve now received a diagnosis of osteoporosis in my hips and spine following a DEXA scan 6 weeks ago. I have GCA diagnosed in April 2021 and have been reducing prednisolone from 60mg to currently 6mg. My rheumatologist wants me to take alendronic acid which I’m worried about. I wonder if
Avon14
in
PMRGCAuk
2 years ago
Cerrelle constant bleeding
I was given the progesterone only pill because I can’t take the combination pill as I have aurora migraines and it increases the risk of stroke. Well I have been bleeding constantly for two weeks. I’ve been on it for 5 weeks. I can handle the annoyance of a constant period but not the pain and discomfort
I was given the progesterone only pill because I can’t take the combination pill as I have aurora migraines and it increases the risk of stroke. Well I have been bleeding constantly for two weeks. I’ve been on it for 5 weeks. I can handle the annoyance of a constant period but not the pain and discomfort
ZebraZone
in
Endometriosis UK
2 years ago
Omega Blood Results
Hello 👋 I take Omega liquid supplement by Now from iHerb, 1.4g a day, high amounts of EPA and DHA. Had a complimentary test from LetsGetChecked and received my Omega 6 to Omega 3 ratio results today: Omega 6: Omega 3 6:1 (1.5-3.0) The report says I should have ratio up to 3:1 and any higher is bad
Hello 👋 I take Omega liquid supplement by Now from iHerb, 1.4g a day, high amounts of EPA and DHA. Had a complimentary test from LetsGetChecked and received my Omega 6 to Omega 3 ratio results today: Omega 6: Omega 3 6:1 (1.5-3.0) The report says I should have ratio up to 3:1 and any higher is bad
Incoguto
in
Thyroid UK
2 years ago
The magic of a backpack
Throughout my life I found myself losing things all the time. In fact I found it very difficult to leave the house sometimes due to the things that I’ve lost or misplaced. One of my girlfriends in the past give me a small bag which are used to store some of the things I needed most commonly. It started
Throughout my life I found myself losing things all the time. In fact I found it very difficult to leave the house sometimes due to the things that I’ve lost or misplaced. One of my girlfriends in the past give me a small bag which are used to store some of the things I needed most commonly. It started
DistractedAlways31
in
CHADD's Adult ADHD Support
2 years ago
Advice on Recent Bloods Please
Hello All, Many thanks again for your help a few weeks ago. I got the postal kit from Lets Get Checked and got the results on Friday. Prior to doing the blood tests I had tried splitting my 2x 60mg NP Thyroid dose into 2 doses - 1 tablet early morning a couple of hours before I am due to get up and the
Hello All, Many thanks again for your help a few weeks ago. I got the postal kit from Lets Get Checked and got the results on Friday. Prior to doing the blood tests I had tried splitting my 2x 60mg NP Thyroid dose into 2 doses - 1 tablet early morning a couple of hours before I am due to get up and the
CMDK2020
in
Thyroid UK
2 years ago
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