Experiences with

Luteinizing hormone releasing hormone (LHRH) agonist

Beginning June 2021 24 months LHRH-agonist. From July till medio September 2021 35x2.2G external radiation. Six weeks thereafter my PSA was less than 0.1 and my Testosteron-value was less than 0.4 nmol/L. PSA stayed at less than 0.1 till last week when it came in at 0.11.

They noted "key takeaways" to include: **Transdermal estradiol is as effective as LHRH agonist and there is no detriment in terms of prostate cancer outcomes or overall survival in starting androgen suppression with transdermal estradiol **Transdermal estradiol provides choice about expected side effects

LHRH agonist therapy completed April 2023. Subsequently he was monitoring his PSA on a two monthly basis. PSA remained undetectable until March 2024. PSA in April 2024 was 0.03, May 2024 was 0.05 and in June 2024 was 0.07. Testosterone in May 2024 was 11.2.

I got, with great difficulty a DEXA scan one month after starting LHRH agonist goserelin. No one told me I needed it, and given my polio as a kid I probably was likely to already have some osteoporosis risk at 73. And yes I had lumber osteoporosis and osteopenia in my hip and neck of femur.

I'm 35 symptoms started at 12 diagnosed at 24 Does anyone have any experience with taking the gnrh agonist as a treatment method?

- Clinical stage from 4/12/2021: Stage IIIC (cT1c, cN0, cM0, PSA: 31.9, Grade Group: 5) -NCCN localized CaP risk group: HIGH RISK 4/2021 - Chemotherapy GnRH Agonist 5/2021 - 6/22/2021 Radiation Oncology EBRT to Prostate and Whole Pelvis with concurrent GnRH Agonist 70 Gy in 28 to pelvis 45

The fracture risk is directly correlated with the number of GnRH agonist doses given.

ADT’s impact on Muscle and Fat October 23, 2023 Standard ADT with either LHRH agonist or antagonist drugs (like Lupron or Firmagon, respectively) cause a loss of lean muscle mass and weight gained as fat. Those are among the most common side effects of ADT.

However, the secondary end point revealed that patients treated with GnRH agonist experienced significantly more major cardiovascular and cerebrovascular events than those treated with GnRH antagonist."

I've just started GNRH agonist injections and my gyno has recommended that I see a dietician alongside treatment. Thanks for your help!

agonist.

Starting LHRH agonist on the first day of radiation therapy, as in the EORTC 22863 study, should be the standard of care when treating locally advanced prostate cancer.

Starting LHRH agonist on the first day of radiation therapy, as in the EORTC 22863 study, should be the standard of care when treating locally advanced prostate cancer.

Satterfield's office regarding his LHRH agonist. Is this all or where to from here??????????

All patients were treated using 400 mg testosterone cypionate intramuscularly every 28 days, together with continuous LHRH agonist therapy. Clinical-grade DNA sequencing was obtained using commercially available assays.

Briefly, patients who had been identified as mCRPC (adenocarcinoma of the prostate with systemic metastatic disease despite castrate levels of testosterone (<50 ng/dl) due to orchiectomy or luteinising hormone-releasing hormone (LHRH) agonist, undergoing ADT (gonadotropin-releasing hormone (GnRH) agonist

The new study analyzed the US electronic medical records of 45,059 men with prostate cancer receiving a luteinizing hormone releasing hormone (LHRH) agonist and antagonist injections. The team examined the rate of MACE within 6 months and 1 year of ADT initiation.

What is your experience with Diphereline or similar GnRH agonist injections?

This was a multi-center, single-arm, open-label phase 2 trial of men with mCRPC who received testosterone cypionate 400mg intramuscular (BAT) every 28 days and nivolumab 480mg IV every 28 days, during which time LHRH agonist treatment was continued.

The GETUG-AFU 16 trial demonstrated that 6 months of luteinizing hormone releasing hormone (LHRH) agonist treatment during salvage RT significantly reduced clinical progression (5-year progression-free survival, 80.0 vs. 62.0%). c.