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Levodopa
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MAOB Inhibitors vs Carbidopa/Levodopa as first prescription for PD
Hi. I'm not new, but have been content to mostly "lurk" and soak up info 'til now. I'm contemplating meds for the first time. I've ruled out dopamine agonists for now--I'm put off by the side effect possibilities. I'm weighing MAOB inhibitors vs C/L. Assuming effectiveness isn't an issue--after all
Hi. I'm not new, but have been content to mostly "lurk" and soak up info 'til now. I'm contemplating meds for the first time. I've ruled out dopamine agonists for now--I'm put off by the side effect possibilities. I'm weighing MAOB inhibitors vs C/L. Assuming effectiveness isn't an issue--after all
sailaway615
in
Cure Parkinson's
4 years ago
Weird things prior to diagnosis that were early clues of PD
Many of these unexplainable things disappeared after starting
levodopa
. Did anyone else have these issues prior to diagnosis? Especially the bottom of foot cramping.
Many of these unexplainable things disappeared after starting
levodopa
. Did anyone else have these issues prior to diagnosis? Especially the bottom of foot cramping.
swva
in
Cure Parkinson's
4 years ago
Study Suggests Mechanism Behind Levodopa-induced Dyskinesia in Parkinson’s
https://parkinsonsnewstoday.com/study-mechanism-behind-
levodopa
-dyskinesia-parkinsons/
https://parkinsonsnewstoday.com/study-mechanism-behind-
levodopa
-dyskinesia-parkinsons/
Gioc
in
Cure Parkinson's
4 years ago
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How do you stop uncontrolled tremors that suddenly come up during the night?
I have had Parkinson's for 11 years, I am taking carbidopa/
levodopa
cr five times a day. Accompanying my tremors is of course much anxiety. Any suggestions on how to relieve this uncomfortable situation???
I have had Parkinson's for 11 years, I am taking carbidopa/
levodopa
cr five times a day. Accompanying my tremors is of course much anxiety. Any suggestions on how to relieve this uncomfortable situation???
James4K
in
Cure Parkinson's
4 years ago
Medicine/Supplement Regime (Mucuna etc)
Also, be patient in introducing new supplements and in seeing results) CBD - half life is 1-2 days - acts like grapefruit juice: inhibits CYP3A4 that breaks
levodopa
down in the body, so less dyskinesia, but also, more
levodopa
gets to the brain - PD Therapeutic Dose: 75-300mg/day https://www.medicalnewstoday.com
Also, be patient in introducing new supplements and in seeing results) CBD - half life is 1-2 days - acts like grapefruit juice: inhibits CYP3A4 that breaks
levodopa
down in the body, so less dyskinesia, but also, more
levodopa
gets to the brain - PD Therapeutic Dose: 75-300mg/day https://www.medicalnewstoday.com
pdkid
in
Cure Parkinson's
4 years ago
Questions about MSA
If I don't take
levodopa
by then I don't really function. Dystonic neck tremor when off
levodopa
or tired, lying down before I sleep or when waking up and often the first thing I feel in the morning and the tremor is in my upper chest as well. Walking and movement slow down as day progresses.
If I don't take
levodopa
by then I don't really function. Dystonic neck tremor when off
levodopa
or tired, lying down before I sleep or when waking up and often the first thing I feel in the morning and the tremor is in my upper chest as well. Walking and movement slow down as day progresses.
rideabike
in
Multiple System Atrophy Trust
4 years ago
How many know that H2, hydrogen water has positive effects for those with Parkinsons? I didn't know.
Methods: In this a placebo-controlled, randomized, double-blind, parallel-group clinical pilot study, the authors assessed the efficacy of H₂ -water in Japanese patients with
levodopa
-medicated PD. Participants drank 1,000 mL/day of H₂-water or pseudo water for 48 weeks.
Methods: In this a placebo-controlled, randomized, double-blind, parallel-group clinical pilot study, the authors assessed the efficacy of H₂ -water in Japanese patients with
levodopa
-medicated PD. Participants drank 1,000 mL/day of H₂-water or pseudo water for 48 weeks.
bepo
in
Cure Parkinson's
4 years ago
When to combine thiamin and prescription meds
She was diagnosed only about 6 weeks ago and started on carbidopa/
levodopa
and then pramiprexole. She started thiamin not long after starting the prescription meds and we have increased the dose so that she's now using 4,000 mg per day.
She was diagnosed only about 6 weeks ago and started on carbidopa/
levodopa
and then pramiprexole. She started thiamin not long after starting the prescription meds and we have increased the dose so that she's now using 4,000 mg per day.
DaisyMakepiece
in
Cure Parkinson's
4 years ago
Trial and error
He's 58, dx 5 years ago and for last 6 months he started Modopar (50mg
levodopa
/ 12.5mg benserazide) 1 caps 3 times a day (6am - 12- 6 pm) taken with 1 x ropinirole (12mg) at 6am. He also takes B1 500mg.
He's 58, dx 5 years ago and for last 6 months he started Modopar (50mg
levodopa
/ 12.5mg benserazide) 1 caps 3 times a day (6am - 12- 6 pm) taken with 1 x ropinirole (12mg) at 6am. He also takes B1 500mg.
Vik38
in
Cure Parkinson's
4 years ago
Recent deterioration in food interference with levodopa
Good morning all, I hope you are all safe and well. I wanted to ask if like me, you have experienced during the recent lockdown some level of deterioration. In my case I have observed that the Sinemet Plus is lasting less time (up to 3 hours in the morning but otherwise, 2 hours if I had food 1 hour
Good morning all, I hope you are all safe and well. I wanted to ask if like me, you have experienced during the recent lockdown some level of deterioration. In my case I have observed that the Sinemet Plus is lasting less time (up to 3 hours in the morning but otherwise, 2 hours if I had food 1 hour
enjoy2013
in
Cure Parkinson's
4 years ago
My Mucuna Trip. Enjoy the humor!
So why not just take Sinemet. https://www.intechopen.com/books/parkinson-s-disease-understanding-pathophysiology-and-developing-therapeutic-strategies/mucuna-and-parkinson-s-disease-treatment-with-natural-
levodopa
I continue to get better and better, I mean a lot better than several years ago.
So why not just take Sinemet. https://www.intechopen.com/books/parkinson-s-disease-understanding-pathophysiology-and-developing-therapeutic-strategies/mucuna-and-parkinson-s-disease-treatment-with-natural-
levodopa
I continue to get better and better, I mean a lot better than several years ago.
Cons10s
in
Cure Parkinson's
4 years ago
How long before levodopa starts working when first introduced?
I note that the C/L equivalent Sinemet capsules/tablets seem to begin with twice the amount of
levodopa
content (100/25) than the Madopar. I’ve been very interested in the posts on thiamine, and will be keen to try it, but it’s probably best to establish the most appropriate dose of Madopar first!
I note that the C/L equivalent Sinemet capsules/tablets seem to begin with twice the amount of
levodopa
content (100/25) than the Madopar. I’ve been very interested in the posts on thiamine, and will be keen to try it, but it’s probably best to establish the most appropriate dose of Madopar first!
Slobber1
in
Cure Parkinson's
4 years ago
Treatments Inadequate for People With Late-stage Disease, Study Says
https://parkinsonsnewstoday.com/2020/06/12/treatments-
levodopa
-inadequate-for-late-stage-parkinsons-patients-study-says/
https://parkinsonsnewstoday.com/2020/06/12/treatments-
levodopa
-inadequate-for-late-stage-parkinsons-patients-study-says/
pvw2
in
Cure Parkinson's
4 years ago
Looking for people who have phased out Carbidopa/Levodopa in favor of an all-mucuna program
I'd like to learn about other people's experiences switching from synthetic to natural
levodopa
, especially if they have eliminated Rytary from their treatment. I'm worried about letting go of the known relief that I get from Rytary.
I'd like to learn about other people's experiences switching from synthetic to natural
levodopa
, especially if they have eliminated Rytary from their treatment. I'm worried about letting go of the known relief that I get from Rytary.
Dupree
in
Cure Parkinson's
4 years ago
My personal withdrawal from the inhibitor EGCG To add the inhibitor quercetin
I have four years used a GCG to complement my intake of natural sourced
levodopa
. I finally got tired of the slight nausea that occurs and decided to try a different type of inhibitor, quercetin. I have found a change beneficial.
I have four years used a GCG to complement my intake of natural sourced
levodopa
. I finally got tired of the slight nausea that occurs and decided to try a different type of inhibitor, quercetin. I have found a change beneficial.
BUZZ1397
in
Cure Parkinson's
4 years ago
5HTP for sleep?
Is it safe to use with carbidopa/
levodopa
? Thanks!
Is it safe to use with carbidopa/
levodopa
? Thanks!
Spottedtowhee
in
Cure Parkinson's
4 years ago
Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson’s disease.
Pmc: Gut bacterial tyrosine decarboxylases restrict levels of
levodopa
in the treatment of Parkinson’s disease. 2019. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338741/
Pmc: Gut bacterial tyrosine decarboxylases restrict levels of
levodopa
in the treatment of Parkinson’s disease. 2019. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338741/
aspergerian13
in
Cure Parkinson's
4 years ago
Levodopa and Eye Pressure
Since then I cut back my
levodopa
and I noticed a difference. Does
levodopa
increase eye pressure? Should I worry.
Since then I cut back my
levodopa
and I noticed a difference. Does
levodopa
increase eye pressure? Should I worry.
Auro1
in
Cure Parkinson's
4 years ago
Continuous / Extended Release
I was offered a generic product, same carbidopa
levodopa
mix, but extended release rather than continuous release. I have been using this for about 6 weeks. I am now really struggling late afternoon, with lots of off time. Is anyone using this generic product? How are you going?
I was offered a generic product, same carbidopa
levodopa
mix, but extended release rather than continuous release. I have been using this for about 6 weeks. I am now really struggling late afternoon, with lots of off time. Is anyone using this generic product? How are you going?
Joynb
in
Cure Parkinson's
4 years ago
Enterococcus faecalis and Carbidopa Levodopa - Some answers
According to this link, posted by aspergerian13 a few days ago, https://www.pnas.org/content/early/2020/04/07/2003785117, researchers have found that
reduced benefits and many side effects of
Carbidopa can be the result of a bacterial decarboxylase enzyme, produced by the commensal gut
According to this link, posted by aspergerian13 a few days ago, https://www.pnas.org/content/early/2020/04/07/2003785117, researchers have found that
reduced benefits and many side effects of
Carbidopa can be the result of a bacterial decarboxylase enzyme, produced by the commensal gut
Parkie-
in
Cure Parkinson's
4 years ago
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