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Imbruvica
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Living with cll
Has anyone had bone and muscle pain after taking
imbruvica
? I've had quite serious pain since being on
imbruvica
for 2 months. What can I do fro this? Thanks Berdine
Has anyone had bone and muscle pain after taking
imbruvica
? I've had quite serious pain since being on
imbruvica
for 2 months. What can I do fro this? Thanks Berdine
berdine
in
CLL Support
9 years ago
Imbruvica
Any one heard about this medicine? Is it for CLL? thanks
Any one heard about this medicine? Is it for CLL? thanks
AAli
in
CLL Support
9 years ago
Here's your opportunity to support the listing of Ibrutinib (Imbruvica) on the Australian PBS - Deadline is next Wed 10th June!
Australia's Pharmaceutical Benefits Advisory Committee (PBAC) - the body that recommends what should be on the PBS, will consider the submission of Ibruitinib for approval in Australia at their July meeting. You can provide a supporting submission on line to the PBAC and it is a well structured process
Australia's Pharmaceutical Benefits Advisory Committee (PBAC) - the body that recommends what should be on the PBS, will consider the submission of Ibruitinib for approval in Australia at their July meeting. You can provide a supporting submission on line to the PBAC and it is a well structured process
AussieNeil
Administrator
in
CLL Support
9 years ago
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CLL and curly hair
I have been on
Imbruvica
(Ibrutinib) since 6/14. Labs have normalized dramatically in eight-nine months.
I have been on
Imbruvica
(Ibrutinib) since 6/14. Labs have normalized dramatically in eight-nine months.
Villager
in
CLL Support
9 years ago
The future for CLL?
There has even been talk that we may have achieved the breakthrough that Imatinib (perhaps better know as Gleevec) was for a sister leukaemia to CLL - CML or Chronic Myelogenous Leukaemia, with some of the new maintenance drugs such as Ibrutinib (
Imbruvica
).
There has even been talk that we may have achieved the breakthrough that Imatinib (perhaps better know as Gleevec) was for a sister leukaemia to CLL - CML or Chronic Myelogenous Leukaemia, with some of the new maintenance drugs such as Ibrutinib (
Imbruvica
).
AussieNeil
Administrator
in
CLL Support
9 years ago
Ibrutinib Treatment Shows Efficacy and Tolerability in Heavily Treated CLL Patients Following Allogeneic Stem Cell Transplant
Here they are showing how effective Ibrutinib (
Imbruvica
) is on a tough to treat bunch of CLL patients. [i]"These patients had a median of five prior therapies and 63% were high-risk del 17p CLL patients. The estimated median progression-free survival (PFS) at 24 months was 76.6%.
Here they are showing how effective Ibrutinib (
Imbruvica
) is on a tough to treat bunch of CLL patients. [i]"These patients had a median of five prior therapies and 63% were high-risk del 17p CLL patients. The estimated median progression-free survival (PFS) at 24 months was 76.6%.
AussieNeil
Administrator
in
CLL Support
9 years ago
New Treatment!
I saw my consultant yesterday and I am to start IBRUTINIB/
IMBRUVICA
within the next two to three weeks. Is there anybody out there who has had or is recieving this treatment, and if so could you please tell me how it is affecting you and do you feel any better. My age now is 72.
I saw my consultant yesterday and I am to start IBRUTINIB/
IMBRUVICA
within the next two to three weeks. Is there anybody out there who has had or is recieving this treatment, and if so could you please tell me how it is affecting you and do you feel any better. My age now is 72.
john133
in
CLL Support
9 years ago
Imbruvica is on track to be a top seller for J&J and Pharmacyclics for years to come
Note the forecast for
Imbruvica
net product revenue of approximately $1 billion in 2015, up 103% from 2014... Neil
Note the forecast for
Imbruvica
net product revenue of approximately $1 billion in 2015, up 103% from 2014... Neil
AussieNeil
Administrator
in
CLL Support
9 years ago
Can anyone confirm if Ibrutinib is now available on prescription in the UK?
Dear Healthcare Professional I am pleased to inform you that Janssen UK has been granted European Medicines Agency (EMA) marketing authorisation for
IMBRUVICA
® (ibrutinib) in the United Kingdom. Prescribing information can be found at the end of this email.
Dear Healthcare Professional I am pleased to inform you that Janssen UK has been granted European Medicines Agency (EMA) marketing authorisation for
IMBRUVICA
® (ibrutinib) in the United Kingdom. Prescribing information can be found at the end of this email.
Ruhi9
in
CLL Support
9 years ago
Epo's
Been on
imbruvica
4 months....hemoglobin is low....not making it.....was put on epo's. ....anybody on epo's and results. ...Thanks
Been on
imbruvica
4 months....hemoglobin is low....not making it.....was put on epo's. ....anybody on epo's and results. ...Thanks
shvantz
in
CLL Support
10 years ago
Hemoglobin
4 months on
imbruvica
...not making rb cells or hemoglobin. ..on epo's now.....terrible fatigue. ...any suggestions. ..thanks my friends
4 months on
imbruvica
...not making rb cells or hemoglobin. ..on epo's now.....terrible fatigue. ...any suggestions. ..thanks my friends
shvantz
in
CLL Support
10 years ago
Ibrutinib monotherapy Clinical Trial latest monitoring - month 40
Wally has fought many skirmishes to put the CLL Bear into hibernation that included a Flavopiridol Trial & now on
Imbruvica
/Ibrutinib.
Wally has fought many skirmishes to put the CLL Bear into hibernation that included a Flavopiridol Trial & now on
Imbruvica
/Ibrutinib.
ThreeWs
in
CLL Support
10 years ago
Update on PCYC-1115-CA Randomised, Phase 3 study of Ibrutinib/Imbruvica versus Chlorambucil in Patients 65 yrs + and untreated with CLL/SLL.
Day 1 of cycle 15 yesterday and continuing onwards and upwards :) FBC looking good with Hg 153.00, WBC 6.7, RBC 4.71, ALC 1.8, platelets 118, neutrophils 4.1. Biochemistry also good with LFT and Renal profile normal and GFR 84.00. LDH 181.00 and B2M 2.4 (norm at Bournemouth lab 1.4 - 2.4) Another
Day 1 of cycle 15 yesterday and continuing onwards and upwards :) FBC looking good with Hg 153.00, WBC 6.7, RBC 4.71, ALC 1.8, platelets 118, neutrophils 4.1. Biochemistry also good with LFT and Renal profile normal and GFR 84.00. LDH 181.00 and B2M 2.4 (norm at Bournemouth lab 1.4 - 2.4) Another
Mikey47
in
CLL Support
10 years ago
FDA Grants Special Protocol Assessment to Phase III Ublituximab/Ibrutinib Study
"TG Therapeutics has reached an agreement with the FDA regarding a Special Protocol Assessment for a phase III clinical trial exploring ublituximab (TG-1101, a chimeric recombinant glycoengineered monoclonal antibody directed against CD20) in combination with ibrutinib (
Imbruvica
) for the treatment of
"TG Therapeutics has reached an agreement with the FDA regarding a Special Protocol Assessment for a phase III clinical trial exploring ublituximab (TG-1101, a chimeric recombinant glycoengineered monoclonal antibody directed against CD20) in combination with ibrutinib (
Imbruvica
) for the treatment of
AussieNeil
Administrator
in
CLL Support
10 years ago
CLL
Anyone else on
Imbruvica
with similar systems, if so how long before things started getting better. I am so tired of not feeling well!
Anyone else on
Imbruvica
with similar systems, if so how long before things started getting better. I am so tired of not feeling well!
Healthyasahorse
in
CLL Support
10 years ago
Approval of Imbruvica Frontline for 17p deleted CLL and Important Trials
Hi Friends, The recent approval of ibrutinib for 17p deletion frontline hopefully is the opening wedge of more indications for treatment naive patients for it and other non-chemo choices. I have posted why this is so important and a list with links to some important clinical trials on my latest blog
Hi Friends, The recent approval of ibrutinib for 17p deletion frontline hopefully is the opening wedge of more indications for treatment naive patients for it and other non-chemo choices. I have posted why this is so important and a list with links to some important clinical trials on my latest blog
bkoffman
CLL CURE Hero
in
CLL Support
10 years ago
Zydelig: The Black Box Warnings for use in CLL
Hi Friends, On my blog (http://bkoffman.blogspot.com), I have commented on the extensive black box warnings on the label for idelalisib or ZYDELIG that is a stark contrast to no black box for ibrutinib, not that
IMBRUVICA
doesn't come with its own set of cautions and concerns.
Hi Friends, On my blog (http://bkoffman.blogspot.com), I have commented on the extensive black box warnings on the label for idelalisib or ZYDELIG that is a stark contrast to no black box for ibrutinib, not that
IMBRUVICA
doesn't come with its own set of cautions and concerns.
bkoffman
CLL CURE Hero
in
CLL Support
10 years ago
Imbruvica/Ibrutinib joint pain side effects
Because joint pain has been experienced by patients on Imbru/Ibru and others have not had this side effect, it is wise to explore all possible causes. I just found this article on a new virus to the US. It has a cool name "Chikungunya" and you thought new drug names were hard to pronounce;-) This virus
Because joint pain has been experienced by patients on Imbru/Ibru and others have not had this side effect, it is wise to explore all possible causes. I just found this article on a new virus to the US. It has a cool name "Chikungunya" and you thought new drug names were hard to pronounce;-) This virus
ThreeWs
in
CLL Support
10 years ago
Update on PCYC-1115-CA Randomised, Phase 3 study of Ibrutinib/Imbruvica versus Chlorambucil in Patients 65 yrs + and untreated with CLL/SLL.
Day 1 of cycle 12 today and with the exception of my platelets, (fluctuating around 100) and my low Immunoglobulins, all counts are in the normal range. Lymphocytes 2.4, LDH 222, B2m 2.8 (a month ago) and WBC 7.5. Biochemistry all in normal range also. A CT scan and possibly BMB next month will reveal
Day 1 of cycle 12 today and with the exception of my platelets, (fluctuating around 100) and my low Immunoglobulins, all counts are in the normal range. Lymphocytes 2.4, LDH 222, B2m 2.8 (a month ago) and WBC 7.5. Biochemistry all in normal range also. A CT scan and possibly BMB next month will reveal
Mikey47
in
CLL Support
10 years ago
Less than the prescribed dosage of Ibrutinib ( Imbruvica) ?
One of the prescribed dosages of
Imbruvica
for one patient with CLL is 140mg, 3 capsules, once per day. Has anyone with CLL experienced taking less than that amount and if so, What have been the results, if any ?
One of the prescribed dosages of
Imbruvica
for one patient with CLL is 140mg, 3 capsules, once per day. Has anyone with CLL experienced taking less than that amount and if so, What have been the results, if any ?
Soflajoe
in
CLL Support
10 years ago
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