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Unsure of best option in early prostate cancer diagnosis.
I have had PSA tests annually for 10 years and in Oct 2023 had an elevated 6.42 result. Was referred to a urologist, whom performed a DRE. There was prostate enlargement but no tumor discovered through DRE. After discussing several options, I decided to have a biopsy on Nov 21, 2023. Dec 5, 2023,
I have had PSA tests annually for 10 years and in Oct 2023 had an elevated 6.42 result. Was referred to a urologist, whom performed a DRE. There was prostate enlargement but no tumor discovered through DRE. After discussing several options, I decided to have a biopsy on Nov 21, 2023. Dec 5, 2023,
cobrasc429
in
Advanced Prostate Cancer
7 months ago
high b12 high mch and mcv
Hi, b12 797 (145 - 637) folate 35.1 (7 - 39) mch 37.6 (27.4 - 33.9) mcv 110 (83 - 97) iron 12 (8 - 30) ferritin 69.30 (13 - 150) haemoglobin 124 (119 - 157) What does this mean? I am not taking b12 supplements or injections. My GP said that I had a b12 deficiency (she didn't measure my b12),
Hi, b12 797 (145 - 637) folate 35.1 (7 - 39) mch 37.6 (27.4 - 33.9) mcv 110 (83 - 97) iron 12 (8 - 30) ferritin 69.30 (13 - 150) haemoglobin 124 (119 - 157) What does this mean? I am not taking b12 supplements or injections. My GP said that I had a b12 deficiency (she didn't measure my b12),
nyx19
in
Pernicious Anaemia Society
4 months ago
vitamin D and magnesium deficiency from B12 loading doses
good day, I'm on my sixth month of loading methy B12 and learning so much on with every ones posts, I am trying to balance out my cofactors now that I've started to feel better along this journey. So with other factors I'm finding out I'm deficient in from all my gastritis from B12 deficiency for several
good day, I'm on my sixth month of loading methy B12 and learning so much on with every ones posts, I am trying to balance out my cofactors now that I've started to feel better along this journey. So with other factors I'm finding out I'm deficient in from all my gastritis from B12 deficiency for several
JesusMercy60
in
Pernicious Anaemia Society
4 months ago
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I am still struggling with treatment decisions - Help please.
I am struggling to decide on my treatment. The main point of conflict is HT or not, and LDR Brachytherapy (if I am eligible - because of a previous HOLEP) or IMRT. I also wonder if I should push hard for a 10-day earlier consultation at the risk of bad feeling. I welcome advice. In the UK - Referral
I am struggling to decide on my treatment. The main point of conflict is HT or not, and LDR Brachytherapy (if I am eligible - because of a previous HOLEP) or IMRT. I also wonder if I should push hard for a 10-day earlier consultation at the risk of bad feeling. I welcome advice. In the UK - Referral
Nordman
in
Advanced Prostate Cancer
7 months ago
Cause of RLS - another step
Brain Iron Dysregulation in Iron Deficiency Anemia-Related Restless Leg Syndrome Revealed by Neuron-Derived Extracellular Vesicles: A Case–Control Study Apostolos Manolopoulos, MD ,1 William York, BS,1 Krishna Ananthu Pucha, BS,1 Christopher J. Earley, MBBCh, PhD,2 and Dimitrios Kapogiannis, MD1
Brain Iron Dysregulation in Iron Deficiency Anemia-Related Restless Leg Syndrome Revealed by Neuron-Derived Extracellular Vesicles: A Case–Control Study Apostolos Manolopoulos, MD ,1 William York, BS,1 Krishna Ananthu Pucha, BS,1 Christopher J. Earley, MBBCh, PhD,2 and Dimitrios Kapogiannis, MD1
RLSLearner
in
Restless Legs Syndrome
4 months ago
Know your Biomarker … Know Your Mutation
KRAS mutation in colorectal cancer is an abnormal change in the KRAS gene, which is involved in controlling cell growth and survival. 40% of CRC has a KRAS mutation. There are more than 25 ongoing clinical trials studying treatments for KRAS-mutated colorectal cancer. Learn more about the KRAS biomarker
KRAS mutation in colorectal cancer is an abnormal change in the KRAS gene, which is involved in controlling cell growth and survival. 40% of CRC has a KRAS mutation. There are more than 25 ongoing clinical trials studying treatments for KRAS-mutated colorectal cancer. Learn more about the KRAS biomarker
GCCA-Survivor
Administrator
in
Colon Cancer Connected
7 months ago
Haematologist’s unsupportive B12 response
In a recent pathology test, my gastroenterologist was concerned with my low haemoglobin count and a high reticulocyte count. She mentioned that although I’m low in ferritin (40) I’m not yet needing an iron infusion just yet. My white cell count was seemingly low also and she suggested that I should get
In a recent pathology test, my gastroenterologist was concerned with my low haemoglobin count and a high reticulocyte count. She mentioned that although I’m low in ferritin (40) I’m not yet needing an iron infusion just yet. My white cell count was seemingly low also and she suggested that I should get
GoneWithTheWind1972
in
Pernicious Anaemia Society
4 months ago
Staying on Ibrance & Anastrozole after 2 recurrences
I’ve been on Ibrance and Anastrozole for the last 6 years for metastatic endometrial cancer. I started out on the Ibrance125 mg and after a couple of years, had a problem recovering on the week off, so my dose was reduced to 100 mg. By spring this year, the counts could not recover on the week off,
I’ve been on Ibrance and Anastrozole for the last 6 years for metastatic endometrial cancer. I started out on the Ibrance125 mg and after a couple of years, had a problem recovering on the week off, so my dose was reduced to 100 mg. By spring this year, the counts could not recover on the week off,
Merma
in
SHARE Metastatic Breast Cancer
7 months ago
Iron Levels
I am a 74-year-old woman living in New Zealand. I was on Ropinirole for restless legs for approximately 3 years. Augmentation set in and I saw his forum went to my doctor who has changed my medication to Pregabalin. Currently on 50mg per day as I weaned off Ropinirole (completely weaned off for 3 nights
I am a 74-year-old woman living in New Zealand. I was on Ropinirole for restless legs for approximately 3 years. Augmentation set in and I saw his forum went to my doctor who has changed my medication to Pregabalin. Currently on 50mg per day as I weaned off Ropinirole (completely weaned off for 3 nights
Brufax
in
Restless Legs Syndrome
4 months ago
diverticulosis, itis, IBS etc
Hi everyone, I’ve taken note of discussions on here regarding gut issues vis a vis under active thyroid. Does levothyroxine of itself also cause gut issues? Many thanks.
Hi everyone, I’ve taken note of discussions on here regarding gut issues vis a vis under active thyroid. Does levothyroxine of itself also cause gut issues? Many thanks.
Calceolaria
in
Thyroid UK
4 months ago
Stopping iron supplement
Hi all hope everyone is well. I am going to have a iron blood test. How many days before the test do i stop my iron supplement?
Hi all hope everyone is well. I am going to have a iron blood test. How many days before the test do i stop my iron supplement?
giggy63
in
Thyroid UK
4 months ago
Ovary discomfort a month after failed ET.
I’ve been experiencing some dull aches in my ovary over the last few days. Occasionally I get sharp pains in my ovary, although I have always had this now and again. It has been about a month since my ET which failed and I have had a bleed since. And I have already ovulated. I spoke to my clinic and
I’ve been experiencing some dull aches in my ovary over the last few days. Occasionally I get sharp pains in my ovary, although I have always had this now and again. It has been about a month since my ET which failed and I have had a bleed since. And I have already ovulated. I spoke to my clinic and
Saskiahope
in
Fertility Network UK
4 months ago
Squamous cell Carcinoma
HERE’S WHAT TO LOOK OUT FOR: Small, hard white or skin coloured lumps. SCCs often first appear on the skin like this. A persistent, scaly red patch with irregular borders. These can sometimes crust or bleed. An elevated growth with a central depression A growth of this type may rapidly increase
HERE’S WHAT TO LOOK OUT FOR: Small, hard white or skin coloured lumps. SCCs often first appear on the skin like this. A persistent, scaly red patch with irregular borders. These can sometimes crust or bleed. An elevated growth with a central depression A growth of this type may rapidly increase
SkcinHQ
Partner
in
Skin Cancer UK
7 months ago
Orchiectomy and Psa
Can anyone who has had Bilateral Ochiectomy tell me if there is a certain psa level required before surgery can be done. Thanks Guys Knittingque
Can anyone who has had Bilateral Ochiectomy tell me if there is a certain psa level required before surgery can be done. Thanks Guys Knittingque
Knittingque
in
Advanced Prostate Cancer
7 months ago
Increased my ferritin levels
Hi all,I have known about the RLS/iron link for many years however as my ferritin iron level has always been around 100 I haven't taken iron consistently.Five months ago I started "getting serious " in taking it every other night with vitamin C as even with my Zomorph and Pregablin I was still getting
Hi all,I have known about the RLS/iron link for many years however as my ferritin iron level has always been around 100 I haven't taken iron consistently.Five months ago I started "getting serious " in taking it every other night with vitamin C as even with my Zomorph and Pregablin I was still getting
Pippins2
in
Restless Legs Syndrome
4 months ago
unknown rash
hi everyone! Last week I posted pictures of my son’s face rash asking if it looked like cutaneous lupus. For those who are just reading now, he had this rash for about two months now— started on his ear which was raw red then went away. A few weeks later the rash developed bright red spots on his face
hi everyone! Last week I posted pictures of my son’s face rash asking if it looked like cutaneous lupus. For those who are just reading now, he had this rash for about two months now— started on his ear which was raw red then went away. A few weeks later the rash developed bright red spots on his face
Demaso33
in
LUPUS UK
3 months ago
Chronic Pain,and fear.
Hi All,I’m hoping for some advice off anyone on here who suffers with flare ups of Diverticulitis. I won’t go into my full story ,as I would be here all day. Basically I’m 80yrs old,and about 9mths ago I was told I have Diverticula,just to add to all my other problems. Well I’ve had about 5 flare
Hi All,I’m hoping for some advice off anyone on here who suffers with flare ups of Diverticulitis. I won’t go into my full story ,as I would be here all day. Basically I’m 80yrs old,and about 9mths ago I was told I have Diverticula,just to add to all my other problems. Well I’ve had about 5 flare
Breathless1943
in
Bowel Disease Support
4 months ago
Really lost - doctor advised me to stop injecting and now B12 keeps going down
Hi everyone, First, I want to say how much this group has been a help and source of comfort and much needed information! Thank you. In Feb 2019 I was diagnosed as having "Vitamin B12 deficiency anemia due to intrinsic factor deficiency." At the time I was 35. My doctor did not say "Pernicious Anemia
Hi everyone, First, I want to say how much this group has been a help and source of comfort and much needed information! Thank you. In Feb 2019 I was diagnosed as having "Vitamin B12 deficiency anemia due to intrinsic factor deficiency." At the time I was 35. My doctor did not say "Pernicious Anemia
marlesk
in
Pernicious Anaemia Society
4 months ago
Pain and Laxido
Ive been taking Laxido for eight months now for recurring impactions and now down to one a day where I do a good BM most days but the last week started to get the most awful stomach pain and bloating which lasts all day . Has anybody else experienced this after taking this product for quite a while
Ive been taking Laxido for eight months now for recurring impactions and now down to one a day where I do a good BM most days but the last week started to get the most awful stomach pain and bloating which lasts all day . Has anybody else experienced this after taking this product for quite a while
Shopnow1
in
IBS Network
4 months ago
Food sensitivities
Hi everyone, just looking for a bit advice re food issues. I have had long term issues with constipation, which resolved when I went dairy free. I also find I feel much better on a gluten free diet so have been GF and DF for about 1 year. These are both very tricky to manage when eating out and I know
Hi everyone, just looking for a bit advice re food issues. I have had long term issues with constipation, which resolved when I went dairy free. I also find I feel much better on a gluten free diet so have been GF and DF for about 1 year. These are both very tricky to manage when eating out and I know
DaisyTed
in
Thyroid UK
4 months ago
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