Experiences with

Fludarabine, cyclophosphamide and rituximab (FCR)

I’m 6 years post FCR

I am 6 years since FCR treatment and to date still doing well not near further treatment ( fingers crossed) my daughter lives in South Africa I’m in Scotland and looking to visit her next year. Does anyone have advice on travel insurance best options who does the best at best rate etc.

And yet we don't seem to talk about it quite as much on here as Ibrutinib and FCR. Just this month a very helpful and quite detailed review article has been released. It is well worth a look whether you are in watch and wait, remission, or coming up for treatment.

Well, it's the evening before I start FCR and a friend has sent me cut flowers. There is conflicting info on line, some sights say no flowers or plants in the house at all and others say just not in the bedroom. Any thoughts?

Did the usual watchful waiting till 2009, then had FCR for 6 months. Went into total remission till 2016... Had AIHA in September of 2018, treated in hospital with 4 transfusions ,and prednisone. My cll is back & I started imbruvica 3 days ago.

Hi members ..i complete my final FCR treatment in the UK on October 11th..we have a motorhome and have been travelling around the UK in it during treatment when I have been well..the question is we would like to travel to spain in it 5 weeks after treatment completes to our holiday home there for a

superior to FCR in IGHV [i]unmutated[/i] patients but [i]not in IGHV mutated[/i] patients.

Paul is well ( he had FCR about 4 years ago), although his numbers are trending towards more CLL treatment . Thanks for any advice. Look after yourselves and each other, Fran 😉

I dont want a reaction doing it too early ..even makeup caused irritation shortly after FCR started so a bit apprehensive for hair dye ...

I have just had my latest 6 monthly ‘Watch and Wait’ blood tests and Flair trial assessment 3 years on from commencement of FCR chemotherapy.

I was talking to someone else with PD and told them I took 100cr every 2+half hours and they told me that it was dangerous to take them so often as the were designed to be take every 4+ hours . I’m worried now as are regular Sinemet,gives me even less on time Has anyone heard this I would like to

In the end I chose FCR rather than entering the Flair trial as my markers met with a good outcome from FCR.

He decided to treat with FCR (fludaribine, cyclophosphamide, but stopped after only 2 cycles because she was not tolerating it well. She was 72 at this stage. Ibrutinib then became available at reasonable cost in Australia so he started her on daily 420 mg.

Four years ago he had FCR and found that very tough. However so far, so good...... Happy to provide updates if it helps others Beryl

In analyzing which patients derived the most benefit from the former standard of care, Jain said data from prior studies showed frontline FCR therapy resulted in favorable long-term progression-free survival (PFS) in patients with IGHV mutations who had achieved undetectable minimal residual disease

For those of us who have had FCR chemotherapy would we expect to be immunocompromised in the long-term? I think here lymphocyte and neutrophil levels are relevant.

In Switzerland they propose FCR treatment and have said outcomes are generally the same. I have read differently. Any insights? Can you direct me to articles? Thank you, his wife

After my daughter25 years sll patients had taken the first dose of FCR the glands in her neck responded and Her size reduces and then returned to inflation again before the time of the second dose Is this normal

When I finished FCR in 4/2014 my blood showed MRD negative. Since than it showed starting 2/2015 CLL of 0,1 - 0,5% in 10/2017. next in 2018 UMRD as they told me, it was undetectable. In 10/2018 it was 0,01 % and in 5/2019 0,02%! Looks like 16 out of 10.000 lymphocytes.

On W&W until 2017 when I had one cycle of FCR, after a bad reaction in intensive care with neutropenic sepsis I recovered and in remission for 18 months until now. My blood counts during this remission have been reasonably stable, around the 130 HGB and below 9 WBC.