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Experiences with
Fludarabine, cyclophosphamide and rituximab (FCR)
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Long-Term Data Showcase the Clinical Utility of Fixed-Duration Venetoclax/Obinutuzumab in Treatment-Naïve CLL
We also know that some intensive chemoimmunotherapies increase the risk of specific malignancies, such as secondary acute myeloid leukemia after an
FCR
[fludarabine, cyclophosphamide, and rituximab (Rituxan)] treatment, so we have a particular focus of looking at secondary malignancies.
We also know that some intensive chemoimmunotherapies increase the risk of specific malignancies, such as secondary acute myeloid leukemia after an
FCR
[fludarabine, cyclophosphamide, and rituximab (Rituxan)] treatment, so we have a particular focus of looking at secondary malignancies.
lankisterguy
Volunteer
in
CLL Support
3 years ago
bmb showing partial remission after 6mnths fcr treatment
hi all ive had my bone marrow results which shows. pr. partial remission after 6 cycles of
fcr
finished in Jan 2021...unmutated,,,bloods show ..hb..112...plts.55...neuts..0.7 ..wbc..2.0...my question his,,is this a bad thing the p.r.and as anyone else who is un mutated had the same ,,,thank you ..kell
hi all ive had my bone marrow results which shows. pr. partial remission after 6 cycles of
fcr
finished in Jan 2021...unmutated,,,bloods show ..hb..112...plts.55...neuts..0.7 ..wbc..2.0...my question his,,is this a bad thing the p.r.and as anyone else who is un mutated had the same ,,,thank you ..kell
kel555
in
CLL Support
3 years ago
Ageing pet’s effect on my health
I love her dearly, but I have noticed I cough a lot when I get up and having done some research online, I am now worried about her affect on my lungs and - post
FCR
- my chances of developing lung cancer. Any thoughts from our wonderful community?
I love her dearly, but I have noticed I cough a lot when I get up and having done some research online, I am now worried about her affect on my lungs and - post
FCR
- my chances of developing lung cancer. Any thoughts from our wonderful community?
Mandy56
in
CLL Support
3 years ago
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Nausea with FCR
I have just finished day 5 of my first cycle of
fcr
. The first day I felt fine but every day since I have had terrible nausea and also physically been sick. Does anyone know if this stops now i have finished the 5 days oral chemo and any advice on how they coped with it. Thanks x
I have just finished day 5 of my first cycle of
fcr
. The first day I felt fine but every day since I have had terrible nausea and also physically been sick. Does anyone know if this stops now i have finished the 5 days oral chemo and any advice on how they coped with it. Thanks x
Daisy1993
in
CLL Support
3 years ago
VACCINE ANTIBOBY TEST STUDY
My history so maybe you can relate; 12 year veteran,
FCR
, Ibrutanib, Venclaxta now on cycle #16 of LOXO-305. 11q deleted C-481 mutation, and currently in REMISSION.
My history so maybe you can relate; 12 year veteran,
FCR
, Ibrutanib, Venclaxta now on cycle #16 of LOXO-305. 11q deleted C-481 mutation, and currently in REMISSION.
steve5441
in
CLL Support
3 years ago
blood results after 9 week fcr finished
hi all,,, went for my blood review today 9 week after cycle 6
fcr
finished ,,wbc.106....plts 34.....HB.108.....neuts.0.5........ not to happy with these results can anyone help me with these as iam thinking does the body take time to recover after 6 months of
FCR
,,,,got a couple of mouth ulcers and feeling
hi all,,, went for my blood review today 9 week after cycle 6
fcr
finished ,,wbc.106....plts 34.....HB.108.....neuts.0.5........ not to happy with these results can anyone help me with these as iam thinking does the body take time to recover after 6 months of
FCR
,,,,got a couple of mouth ulcers and feeling
kel555
in
CLL Support
3 years ago
NICE Approves Acalabrutinib (Calquence) for specified groups of CLL patients in England
Patients for whom chlorambucil would've been an option at that time would have been the less fit patients who could not have tolerated
FCR
or BR.
Patients for whom chlorambucil would've been an option at that time would have been the less fit patients who could not have tolerated
FCR
or BR.
Jm954
in
Leukaemia Support
3 years ago
NICE Approves Acalabrutinib (Calquence) for specified groups of CLL patients in England
Patients for whom chlorambucil would've been an option at that time would have been the less fit patients who could not have tolerated
FCR
or BR.
Patients for whom chlorambucil would've been an option at that time would have been the less fit patients who could not have tolerated
FCR
or BR.
Jm954
Administrator
in
CLL Support
3 years ago
New guy here, just want to share my story.
A barrage of blood tests were ordered and to summarize the results, I had everything one could want and nothing you wouldn't want, so I was the perfect candidate for
FCR
with great chance for a long remission.
A barrage of blood tests were ordered and to summarize the results, I had everything one could want and nothing you wouldn't want, so I was the perfect candidate for
FCR
with great chance for a long remission.
CallmeT
in
CLL Support
3 years ago
First Time Post: CLL in full relapse mode + vaccines and Calquence next line of defense.
Unfortunately my leukemia is back after nearly 2 years of remission with
FCR
. I’ve undergone the typical CLL tests and was ‘relieved’ to find it had not transformed into anything worse - so I got that going for me.
Unfortunately my leukemia is back after nearly 2 years of remission with
FCR
. I’ve undergone the typical CLL tests and was ‘relieved’ to find it had not transformed into anything worse - so I got that going for me.
TimDeeSeattle
in
CLL Support
3 years ago
NICE Recommends Acalabrutinib for treating CLL for certain groups
People with untreated CLL without a 17p deletion or TP53 mutation usually have
FCR
or BR. If
FCR
or BR is unsuitable, chlorambucil plus obinutuzumab is offered instead.
People with untreated CLL without a 17p deletion or TP53 mutation usually have
FCR
or BR. If
FCR
or BR is unsuitable, chlorambucil plus obinutuzumab is offered instead.
Jm954
Administrator
in
CLL Support
3 years ago
Chest pain in CLL
Hi all am waiting to start
fcr
treatment for my cll quite soon, but for the past 3 week's I've been suffering from tightness and slight pain in the middle and right side of my chest. Had my heart checked and all ok. Just wondering if anyone has had this problem Thank you
Hi all am waiting to start
fcr
treatment for my cll quite soon, but for the past 3 week's I've been suffering from tightness and slight pain in the middle and right side of my chest. Had my heart checked and all ok. Just wondering if anyone has had this problem Thank you
Daisy1993
in
CLL Support
3 years ago
bloods not going up
hi all went the hospital today for check and review plts 36 ,,neuts 0.4 ,,hb 108,,,having one gscf injection every week.. 9 week post
fcr
,,,my numbers don,t seem to be going up my neuts have actually dropped from 0.5 to 0.4 is there anything else they can to raise the blood numbers or is it just a waiting
hi all went the hospital today for check and review plts 36 ,,neuts 0.4 ,,hb 108,,,having one gscf injection every week.. 9 week post
fcr
,,,my numbers don,t seem to be going up my neuts have actually dropped from 0.5 to 0.4 is there anything else they can to raise the blood numbers or is it just a waiting
kel555
in
CLL Support
3 years ago
Which vaccine is better for CLL patients, Pfizer or Astra Zeneca ?
After 5 years of slow raising , at 134000 WBC I had
FCR
chemo, only two cycles, as I reacted with high fever to Rituximab and blood count droped down to 8000 immediately, so twice the second day of Cyclofosfamid was cancelled and unfortunately I did suffer from Clostridium Difficile after each treatment
After 5 years of slow raising , at 134000 WBC I had
FCR
chemo, only two cycles, as I reacted with high fever to Rituximab and blood count droped down to 8000 immediately, so twice the second day of Cyclofosfamid was cancelled and unfortunately I did suffer from Clostridium Difficile after each treatment
Ankakoza
in
CLL Support
3 years ago
Astra Zeneca - any reactions?
I am so much more sensitive to all kinds of things since
FCR
two and a half years ago. Anyway, small price to pay for not getting covid.
I am so much more sensitive to all kinds of things since
FCR
two and a half years ago. Anyway, small price to pay for not getting covid.
Mandy56
in
CLL Support
3 years ago
Inevitable, but still a blow and a huge disappointment
Over 10 years diagnosed with CLL and after a 4 year remission following
FCR
, I have just been told that my lymphocyte levels has just risen to just over 5 (Outside the upper scale of normal).
Over 10 years diagnosed with CLL and after a 4 year remission following
FCR
, I have just been told that my lymphocyte levels has just risen to just over 5 (Outside the upper scale of normal).
Rich316
in
CLL Support
3 years ago
not sure
I all ,i started treatment august 2020
FCR
, i was doing fine no problems until my 3 cycle October i seem to have a slight cough which would did not go away as time went on it got worse ,i was due to start my 4 cycle so i went to my doctors for a review before treatment i told him about the cough and
I all ,i started treatment august 2020
FCR
, i was doing fine no problems until my 3 cycle October i seem to have a slight cough which would did not go away as time went on it got worse ,i was due to start my 4 cycle so i went to my doctors for a review before treatment i told him about the cough and
kel555
in
CLL Support
3 years ago
Exercising and walking when your muscles are stiff
Is high intensity exercises or long walks advisable if you have sore stiff muscles? I always thought being active as much as possible was suppose to be helpful for people with Parkinson's, but in my case it seems to make the stiffness worse the following day. Maybe it's because I'm doing some of the
Is high intensity exercises or long walks advisable if you have sore stiff muscles? I always thought being active as much as possible was suppose to be helpful for people with Parkinson's, but in my case it seems to make the stiffness worse the following day. Maybe it's because I'm doing some of the
Doohat
in
Cure Parkinson's
3 years ago
Health Canada approves Ibrutinib plus Rituximab for First Line Treatment of Patients with Chronic Lymphocytic Leukemia (CLL)
The risk of disease progression or death was reduced by 66 per cent in the IMBRUVICA® arm compared with
FCR
, with a median follow-up time of 37 months.
The risk of disease progression or death was reduced by 66 per cent in the IMBRUVICA® arm compared with
FCR
, with a median follow-up time of 37 months.
AussieNeil
Partner
in
CLL Support
3 years ago
Wearing Off or Dyskinesia
Wearing Off or Dyskinesia Author: Jill Marjama-Lyons, MD and Mary J. Shoman ….possible changes to your medicines…discuss with your doctor. •Use Sinemet CR (controlled release) or Sinemet ER (extended release). •Add a dopamine agonist. •Add a COMT inhibitor to Sinemet (immediate release, CR form
Wearing Off or Dyskinesia Author: Jill Marjama-Lyons, MD and Mary J. Shoman ….possible changes to your medicines…discuss with your doctor. •Use Sinemet CR (controlled release) or Sinemet ER (extended release). •Add a dopamine agonist. •Add a COMT inhibitor to Sinemet (immediate release, CR form
Hidden
in
Cure Parkinson's
3 years ago
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