blood results after 9 week fcr finished

[kel555]

hi all,,, went for my blood review today 9 week after cycle 6 fcr finished ,,wbc.106....plts 34.....HB.108.....neuts.0.5........ not to happy with these results can anyone help me with these as iam thinking does the body take time to recover after 6 months of FCR,,,,got a couple of mouth ulcers and feeling a bit light headed ,,,many thanks ,,kell

[Jm954 Administrator]

Your results are very low for 9 weeks post FCR, it's known as delayed recovery and not that rare.

It's these sort of toxicities that is encouraging the move away from FCR to targeted treatments even for those that might be expected to do well, long term, with FCR.

I hope your counts start to recover soon but it may be some time and a bone marrow biopsy may be needed to be sure of what is going on here. There is also the outside possibility that they may never recover. Please discuss with your Dr and get their opinion on this.

Please let your doctor know that you have the ulcers and are feeling lighted headed. They need to follow you up carefully.

Best wishes, keep us updated

Jackie

[kel555 in reply to Jm954]

thanks Jackie ,got a phone call today the doctors put me on folic acid and 1 injection once a week for 4 weeks and some antibiotics ,,,,iam a bit botherd about that MDS which you can get ive been told so fingers crossed ,iam unmutated i dont know my deletion also iam atm negative and tp53 negative ,,,so god knows ,,,kell

[Jm954 Administrator in reply to kel555]

I think that will probably be B12 injections Kell, so they are doing all they can to give your bone marrow every opportunity to make the cells you need. I hope this all helps, please let us know what your results are like when you have them done again.

Take care

Jackie

[GMa27]

What are your markers?

I am 13q mutated and had 3 rounds of FCR. Got tested and was able to stop.

The first day of chemo my WBC went from 225 down to 60. I was anemic before treatment....my HGB was normal after first round.

It does take 6 months to a year for certain levels to get better. My platelets after 2 years in remission just moved into the low end of normal range. But yours is quite low. WBC is still high.

Were you given choices of treatments? What does your Hematologist think? Let your doctor know your symptoms. 💕

[kel555 in reply to GMa27]

thankyou

[very]

My husband, had 6 cycles of FCR in 2016 ,i would say it took 12months for his immune system to recover .He had a BM and CT scan after 3 months . His BM was clear and his scan was back to its normal size. He is having a CT scan on on the 9th of March as part of the FCR trial.

jenny uk

[kel555 in reply to very]

thankyou

[LeoPa]

Do you qualify now for targeted treatments if the chemo does not prove helpful for long? Hope you get better soon and have a better treatment option next time.

[kel555 in reply to LeoPa]

i hope so

[bennevisplace]

Hi kel555. I also did 6 cycles of FCR and it has taken much longer than 9 weeks for my blood values to recover. 12 months on, haemoglobin and platelets are getting there while lymphocytes and neutrophils are still way down. Other members here have reported recovery times of 6 months, even 18 months. I expect your haematologist will have seen this kind of variability, so I would go along with his/ her assessment for now.

As part of the trial, you should get a bone marrow test 3 months after finishing treatment, which will better inform your haemo as to how you're doing.

PS get a referral for the mouth ulcers. FCR makes you highly vulnerable to infections. I had that too, and even the specialist missed the cause until biopsy nailed it.

[kel555 in reply to bennevisplace]

hi and thank you for your reply ,can i ask you what was the cause for the mouth ulcers ,,,kell

[bennevisplace in reply to kel555]

The oral surgeon was stymied. Biopsy showed an infection "consistent with herpes simplex virus" and later a different doctor diagnosed it as herpes zoster, i.e. shingles (which by the way I had had on the body less than a year before). Either way, the remedy was Aciclovir, which many CLL patients will be familiar with. I took it for a week, the sores disappeared then returned. Now I'm on Aciclovir indefinitely it's all clear.

[kel555 in reply to bennevisplace]

yes iam on the same meds i will keep you informed ,,thankyou

[RSixtyThree]

I finished FCR mid 2020. Took 6 months for my neutrophils to climb high enough to avoid mouth sores. My neutrophils and lymphocyte counts are still below the normal range. My hemoglobin and platelets have recovered.