Experiences with

Estradiol / Norgestrel

Hello, so I feel as though I’m back to square one, my Gynecologist gave me Estradiol cream because of the severe burning I’m experiencing. The dose is 0.5g twice a week, I felt it was not helping so asked if I could use it more often, she said no, the maximum dose is 3 times per week. (???) I’ve read

Strategies to Resensitize CRPC to AR-Targeted Therapies Castration-resistant prostate cancer (CRPC) often remains driven by the androgen receptor (AR) pathway despite resistance to standard AR-targeted treatments. Numerous strategies – from drugs and combinations to hormonal cycling and lifestyle changes

Maybe beating this horse to death... Estrogen Therapy (e.g., Transdermal Estradiol) o Previously used but abandoned due to heart-related side effects with oral estrogen. o Transdermal estradiol (PATCH trial) is being reconsidered as a safer option with potential benefits for bone and metabolic health

These are my latest blood tests from my GP My TSH has lowered since my last private bloods, so they won't test the FT4 or FT3 The surgery phoned about my cholesterol levels, I stopped taking my statins last year. My diet is low carb, I have dairy, but not milk. I eat meat, but not fish. Serum vitamin

Firmly of the opinion that people here 'know' lots of things My new consultant is asking my GP for the following tests: FBC Renal profile Lipid profile - need to check if she wants fasting or non fasting Liver Function tests 9am cortisol - 9am 🙄 LH and FSH and oestradiol Prolactin TSH and FT4

Hey Ladies, I thought I’d ask on here as I’ve been asking myself the questions and going around about it in my head. I’m preparing to have a FET and have been taking Estradiol tablets 200mg x 3 a day. I went to my scan on day 9 of taking the tablets but my lining isn’t quite there yet to start taking

Hi everyone, Im hoping someone who has been through a modified natural FET could share if estrogen was added to your protocol? After several medicated FETS failed I'm preparing for a modified natural FET transfer this Monday with two untested 4CB embryos. My own natural estrogen level before trigger

We have results. Transdermal Estradiol Plus ARPIs Demonstrate Comparable PSA Response to LHRHa in Metastatic Prostate Cancer https://www.onclive.com/view/transdermal-estradiol-plus-arpis-demonstrate-comparable-psa-response-to-lhrha-in-metastatic-prostate-cancer

My wife just got her thyroid tested because she is on HRT and we suspect her estradiol may be causing an issue. Are her results optimal? Here are the results: TSH 1.56 mu/L (normal range 0.27 - 4.2 mU/L) Thyroxine 17.7 pmol/L (normal range 12 - 22 pmol/L) Triodothyronine 4.2 pmol/L (normal range

I think the correct answer may be both. Many of you reading this are aware that most endogenous E2 is due to aromatase conversion of T to E2. So while on ADT, there is little or no endogenous E2, often under 5 pg/mL (mine was < 2). The implication is that during ADT (or loT BAT cycles), a low dose

Hello, I was wondering if anyone has had the side effects of coming off the depot provera shot like I have and was wondering how long it took your hormones to level out? I'm 39 years old and had been on the shot for 20 years with 3 breaks in between. My last shot was in March of last year and about 4

(Tw: decent results) Hi everyone, after over a year of planning (and faffing!), I finally did my egg freezing cycle last week, and got 17 eggs retrieved and 13 frozen. I have a 30 minute follow up with my doc on Monday, and I'd love to know what are the most important questions to ask about my cycle

Dear Friends, I finished the ADT in August 2024 (last injection of Decapeptyl in May 2024) and for fear that the estradiol would hinder the recovery of the TST I almost simultaneously stopped applying extradiol patches (2 per week of 25 mcg) that for almost the duration of the ADT they maintained the

ContainsEthinyl Estradiol (0.03mg)+ Drospirenone (3mg). Contains Ethinyl Estradiol (30mcg)+ Dienogest (2mg) Which one is helpful and more effective for heavy period?. Im waiting for your response Thankyou

hello there, Just wondering if anyone can please give me some advice on vaginal HRT. Thanks in advance. I was diagnosed with vaginal atrophy a couple of years ago - last period was three years ago - I’m 52. I was prescribed 10micrograms of Estradiol pessaries by GP a couple of years ago but I’ve

Hello, My wife and I recently moved to the UK from the US and we're having an issue. She suffers from hypothyroidism, specifically with her T3. TSH is almost always on the lower end of normal despite being on levothyroxine. We know her main issue is with T3 from past experience and have informed the

I have suffered from a hypertonic pelvic floor for years. I also have MS, and the pelvic pain seems to ease or worsen along with other spasticity in my body. I have had difficulty with intercourse (translation: no intercourse) since I was 51. I am now 59. Every single time I have used estradiol cream

This request for some experiences regarding gynecomastia. As such it is probably initially directed at the guys on this brillant forum. But if there are any lady carers/partners of cirrhosis patients with experiences, please assist as well, if you can. My 1st decompensated hospital episode was 9+ years

I feel like...we will soon be all moved to estradiol! A phase 2 study from the STAMPEDE trial found that transdermal estradiol (tE2) patches, when combined with androgen receptor pathway inhibitors (ARPIs), reduce PSA levels as effectively as luteinizing hormone-releasing hormone analogues (LHRHa) in

The results comparing tE2 + ARPI agents to LHRHa + ARPI agents were presented at the ASCO meeting in February, 2025. The primary conclusion is that PSA responses were similar in patients treated with tE2+ARPI or LHRHa+ARPI, further supporting the use of tE2 patches for ADT in prostate cancer management