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Experiences with
Entacapone
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HDT more or less
Currently I'm on levodopa and
entacapone
, taking meds at several intervals /day. As meds wear off before it is time for the next dose, I'm experiencing EXTREME fatigue. It's nearly impossible to stand or move. The fatigue comes on rapidly.
Currently I'm on levodopa and
entacapone
, taking meds at several intervals /day. As meds wear off before it is time for the next dose, I'm experiencing EXTREME fatigue. It's nearly impossible to stand or move. The fatigue comes on rapidly.
Zardoz
in
Cure Parkinson's
2 years ago
Anyone taking GOCOVRI?
I tried
Entacapone
before that and it gave me bad dreams. My questions are; 1) Have you used it? 2). Did/does it help? 3) It is very expensive, it costs $3,900/month. The speciality pharmacy gave me a special deal of $20/ month until I go in Medicare, which will be in January.
I tried
Entacapone
before that and it gave me bad dreams. My questions are; 1) Have you used it? 2). Did/does it help? 3) It is very expensive, it costs $3,900/month. The speciality pharmacy gave me a special deal of $20/ month until I go in Medicare, which will be in January.
laglag
in
Cure Parkinson's
2 years ago
COMPT inhibitors friend or foe?
A physician (not mine ) has suggested
Entacapone
might help reduce the unwanted movement and increase the “on” time . I’m reluctant to add more drugs but diskenesia is limiting my daily activities and driving me to sit on the couch way too much. Any thoughts?
A physician (not mine ) has suggested
Entacapone
might help reduce the unwanted movement and increase the “on” time . I’m reluctant to add more drugs but diskenesia is limiting my daily activities and driving me to sit on the couch way too much. Any thoughts?
134A
in
Cure Parkinson's
2 years ago
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Weighing tablets
The measurements below are raw (uncalibrated) weights (mg) of Stalevo tablets (levodopa 75, carbidopa 18.57,
entacapone
200). 5 tablets were weighed from each of two batches. Each tablet (A to E) was weighed 3 times. The pills came from unopened plastic pill tubs, with a foil cover.
The measurements below are raw (uncalibrated) weights (mg) of Stalevo tablets (levodopa 75, carbidopa 18.57,
entacapone
200). 5 tablets were weighed from each of two batches. Each tablet (A to E) was weighed 3 times. The pills came from unopened plastic pill tubs, with a foil cover.
johntPM
in
Cure Parkinson's
2 years ago
Looking for answer
Has anyone taken
Entacapone
200mg 3 times a day
Has anyone taken
Entacapone
200mg 3 times a day
Knight1963
in
Cure Parkinson's
2 years ago
Medications, supplements and other therapies used in Parkinsons
Ashwagandha Astragalus Azilect Berberine BioVie Brain derived neurotropic factor (BDNF) Black Seed Oil (Nigella Saliva) BMPS/7 Broccoli Sprout Butyric acid B-carotene Cannabis CBD Celastrol Celebrex Choline Cinnamon, Ceylon Coffee Coconut Oil CoEnzyme Q10 Collagen COMT inhibitors (
entacapone
Ashwagandha Astragalus Azilect Berberine BioVie Brain derived neurotropic factor (BDNF) Black Seed Oil (Nigella Saliva) BMPS/7 Broccoli Sprout Butyric acid B-carotene Cannabis CBD Celastrol Celebrex Choline Cinnamon, Ceylon Coffee Coconut Oil CoEnzyme Q10 Collagen COMT inhibitors (
entacapone
healthyheart7
in
Cure Parkinson's
2 years ago
Entacapone
Dear all My consultant has prescribed a drug called
Entacapone
. This was in response to me describing the dramatic down period once my Sinement+ tablet had worn off - it is supposed to lessen / even out the fall. Please does any one have any current views on
Entacapone
- and does it work?
Dear all My consultant has prescribed a drug called
Entacapone
. This was in response to me describing the dramatic down period once my Sinement+ tablet had worn off - it is supposed to lessen / even out the fall. Please does any one have any current views on
Entacapone
- and does it work?
Mocha1263
in
Cure Parkinson's
3 years ago
Dysknesia
I normally take 2 25/100 every 3 hrs, I tried
entacapone
with 1 and 2 pills worked OK, then I was getting dysknesia more often, cut pill
entacapone
in half didn't help, weaned off
entacapone
. I would get dysknesia occasionally, lately every time I take 2 25/100.
I normally take 2 25/100 every 3 hrs, I tried
entacapone
with 1 and 2 pills worked OK, then I was getting dysknesia more often, cut pill
entacapone
in half didn't help, weaned off
entacapone
. I would get dysknesia occasionally, lately every time I take 2 25/100.
akgirlsrock
in
Cure Parkinson's
3 years ago
Weaning off pramipexole
After that start
Entacapone
. I’m almost two weeks in. So far my movement is a struggle and I’m thinking when I get to 0.375 1x daily it can only get worse. If I take the supplement Now Dopa Mucana in the morning it helps. Anyone try weaning pramipexole this way?
After that start
Entacapone
. I’m almost two weeks in. So far my movement is a struggle and I’m thinking when I get to 0.375 1x daily it can only get worse. If I take the supplement Now Dopa Mucana in the morning it helps. Anyone try weaning pramipexole this way?
Jeaner73
in
Cure Parkinson's
3 years ago
Balance with dopamine / choline receptors
I tried
entacapone
for 4 days and gave me dysknesia, I even cut pill in half, it seemed worse in the morning , I'm thinking my ER night pill is still in my system. Also I was feeling a wave of depression that I normally don't feel, had anyone had this feeling with
entacapone
. Thank you, Maria
I tried
entacapone
for 4 days and gave me dysknesia, I even cut pill in half, it seemed worse in the morning , I'm thinking my ER night pill is still in my system. Also I was feeling a wave of depression that I normally don't feel, had anyone had this feeling with
entacapone
. Thank you, Maria
akgirlsrock
in
Cure Parkinson's
3 years ago
? for Entacapone users
For those who have used
entacapone
, did you find it caused you fatigue?
For those who have used
entacapone
, did you find it caused you fatigue?
Zardoz
in
Cure Parkinson's
3 years ago
Opicapone: A third generation COMT inhibitor
• In clinical trials BIPARK I and II, 50 mg of opicapone once daily was shown to be noninferior to
entacapone
and reduced the mean off time by about 50 min when compared to placebo. https://www.sciencedirect.com/science/article/pii/S2590112520300517
• In clinical trials BIPARK I and II, 50 mg of opicapone once daily was shown to be noninferior to
entacapone
and reduced the mean off time by about 50 min when compared to placebo. https://www.sciencedirect.com/science/article/pii/S2590112520300517
Farooqji
in
Cure Parkinson's
3 years ago
Anavex Life Sciences Announces Presentation of Phase 2 Clinical Biomarker Data from ANAVEX®2-73-PDD-001 Parkinson’s Disease Dementia Study
Study participants were allowed to be on stable regimen of anti-Parkinson's disease medications (including levodopa, dopamine agonists, MAO-B inhibitors, or
entacapone
).
Study participants were allowed to be on stable regimen of anti-Parkinson's disease medications (including levodopa, dopamine agonists, MAO-B inhibitors, or
entacapone
).
John_morris71
in
Cure Parkinson's
2 years ago
Agonists list
Have I imagined this Can some kind person on here tell me if
Entacapone
Teva is an agonist
Have I imagined this Can some kind person on here tell me if
Entacapone
Teva is an agonist
M-o-ggy
in
Cure Parkinson's
3 years ago
Entacapone/Comtan question
My husband was just given a prescription for this medication to bridge his off time. I’m not able to find a lot of information on it, as far as how well, or not it is working for folks. He is on C/L 4 to 5 doses a day, and 1 Xadago in the a.m. Anyone have good or bad experiences with this medication
My husband was just given a prescription for this medication to bridge his off time. I’m not able to find a lot of information on it, as far as how well, or not it is working for folks. He is on C/L 4 to 5 doses a day, and 1 Xadago in the a.m. Anyone have good or bad experiences with this medication
1rocketman
in
Cure Parkinson's
3 years ago
Vitamin C in the world of Parkinson´s
Vitamins and
entacapone
in levodopa-induced hyperhomocysteinemia: a randomized controlled study. Neurology. Quiroga (2014). Ascorbate and zinc responsive parkinsonism. Ann Pharmacother. Rabin (1989).
Vitamins and
entacapone
in levodopa-induced hyperhomocysteinemia: a randomized controlled study. Neurology. Quiroga (2014). Ascorbate and zinc responsive parkinsonism. Ann Pharmacother. Rabin (1989).
parkinsonshereandnow
in
Cure Parkinson's
3 years ago
Anavex Announces Ph. 2 results : Improved both Primary Cognitive and Secondary MDS-UPDRS Efficacy EndpointsTreatment of Parkinsons Dementia
Study participants were allowed to be on stable regimen of anti-Parkinson's disease medications (including levodopa, dopamine agonists, MAO-B inhibitors, or
entacapone
).
Study participants were allowed to be on stable regimen of anti-Parkinson's disease medications (including levodopa, dopamine agonists, MAO-B inhibitors, or
entacapone
).
John_morris71
in
Cure Parkinson's
3 years ago
Sinement overdose Effect
Can I please be advised on how to reduce the sinement dose, I also take mannitol powder,
entacapone
teva , but it's not working I want to add pramipexole. What else can I do. Thank you all.
Can I please be advised on how to reduce the sinement dose, I also take mannitol powder,
entacapone
teva , but it's not working I want to add pramipexole. What else can I do. Thank you all.
Masterka
in
Cure Parkinson's
4 years ago
A riddle, wrapped in a mystery, inside an enigma!
increases with each successsive
entacapone
dose?
increases with each successsive
entacapone
dose?
Hidden
in
Cure Parkinson's
4 years ago
Medicine/Supplement Regime (Mucuna etc)
helps with bioavailability - Building block for dopamine, epinephrine, norepinephrine and thyroid hormones; Replenishes cognitive resources used in memory Quercetin - Half life is 3.5 hours - Doses greater than 1gram a day can cause kidney damage - Improves L-Dopa absorption - Has ComT activity like
Entacapone
helps with bioavailability - Building block for dopamine, epinephrine, norepinephrine and thyroid hormones; Replenishes cognitive resources used in memory Quercetin - Half life is 3.5 hours - Doses greater than 1gram a day can cause kidney damage - Improves L-Dopa absorption - Has ComT activity like
Entacapone
pdkid
in
Cure Parkinson's
4 years ago
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