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Slow release cardopa/levodopa
Sometimes it's depends if my food has interfered with pills, and then I'll have to take a muscle relaxant half, I try not to take them, and lately I've been using the Inbrija for when I completely need
dopamine
, and seriously off, especially when I eat protein, I am a meat eater , but it's weird because
Sometimes it's depends if my food has interfered with pills, and then I'll have to take a muscle relaxant half, I try not to take them, and lately I've been using the Inbrija for when I completely need
dopamine
, and seriously off, especially when I eat protein, I am a meat eater , but it's weird because
akgirlsrock
in
Cure Parkinson's
2 years ago
Holistic first consultation of RLS sufferers with their doctor and use of intravenous iron therapy
See my discussion on iron therapy and dispelling the ‘fallacious fear of raised ferritin’ (not the sensible scientific care in avoiding iron overload) Discuss treatment options - intravenous iron, alpha 2 delta ligands , opioids and only if absolutely necessary………………
dopamine
agonists. 9 For those
See my discussion on iron therapy and dispelling the ‘fallacious fear of raised ferritin’ (not the sensible scientific care in avoiding iron overload) Discuss treatment options - intravenous iron, alpha 2 delta ligands , opioids and only if absolutely necessary………………
dopamine
agonists. 9 For those
Kakally
in
Restless Legs Syndrome
2 years ago
Some thoughts on Gluten sensitivity
A brain scan was done on the man that showed abnormalities that were consistent with lower levels of
dopamine
production, which when combined with the clinical data, led the doctor to diagnose him with PD.
A brain scan was done on the man that showed abnormalities that were consistent with lower levels of
dopamine
production, which when combined with the clinical data, led the doctor to diagnose him with PD.
Farooqji
in
Cure Parkinson's
2 years ago
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News that worried us and studies that gave us hope (04/2022).
It also participates in the synthesis of
dopamine
and glutathione. It also inhibits the aggregation of spontaneous alpha-synuclein and that produced by iron (Golts 2002). Magnesium concentration in Parkinson's patients is low.
It also participates in the synthesis of
dopamine
and glutathione. It also inhibits the aggregation of spontaneous alpha-synuclein and that produced by iron (Golts 2002). Magnesium concentration in Parkinson's patients is low.
parkinsonshereandnow
in
Cure Parkinson's
2 years ago
Any scientific papers on DAWS (Dopamine Agonist Withdrawal Syndrome) and/or withdrawing off or tapering down dopamine agonists?
Good afternoon everyone. I had an appointment with my neurologist last week and finally convinced her that I should try reducing my Rotigotine (Neupro patch) medication (currently at 4mg). However, I am not happy with her suggestion/recommendation that I just drop down to 3mg patches. I told her that
Good afternoon everyone. I had an appointment with my neurologist last week and finally convinced her that I should try reducing my Rotigotine (Neupro patch) medication (currently at 4mg). However, I am not happy with her suggestion/recommendation that I just drop down to 3mg patches. I told her that
YodaDog
in
Restless Legs Syndrome
2 years ago
Dr. Jonathan Sackner-Bernstein - "What If I Discovered the Silver Bullet?" on Zoom at 7.30pm London time on Monday 21st Feb
He published his analysis last summer in the Journal of Parkinson’s disease showing that these critical neurons do not lack
dopamine
– they have excess
dopamine
. This led him to design a clinical trial to test a drug that addresses this newly defined mechanism of disease.
He published his analysis last summer in the Journal of Parkinson’s disease showing that these critical neurons do not lack
dopamine
– they have excess
dopamine
. This led him to design a clinical trial to test a drug that addresses this newly defined mechanism of disease.
Michel0220
in
Cure Parkinson's
2 years ago
How many of you have found that exercise helps with your movement? How many of you have tried the ''Fast Walking?'How many succeeded?
That repairs the damaged glial cells and the brain can then produce more
dopamine
and our symptoms improve.
That repairs the damaged glial cells and the brain can then produce more
dopamine
and our symptoms improve.
JohnPepper
in
Cure Parkinson's
2 years ago
AMPA Receptor Excitotoxicity and neurodegeneration.
Second, the CP-AMPAR-induced loss of
dopamine
neurons in the midbrain causes PD-related depression (Zhang et al., 2019).
Second, the CP-AMPAR-induced loss of
dopamine
neurons in the midbrain causes PD-related depression (Zhang et al., 2019).
Hidden
in
Cure Parkinson's
2 years ago
Berberine: Time to nail down the dosage!
Then I look at this study: Oral berberine improves brain dopa/
dopamine
levels to ameliorate Parkinson’s disease by regulating gut microbiota 2021 https://www.nature.com/articles/s41392-020-00456-5 and they prescribed humans 500 mg twice a day.
Then I look at this study: Oral berberine improves brain dopa/
dopamine
levels to ameliorate Parkinson’s disease by regulating gut microbiota 2021 https://www.nature.com/articles/s41392-020-00456-5 and they prescribed humans 500 mg twice a day.
Bolt_Upright
in
Cure Parkinson's
2 years ago
small study, but researchers report evidence of picornavirus antigen in 7 of 9 Parkinsons postmortem samples of midbrain
Picornavirus May Be Linked to Parkinson’s Disease through Viral Antigen in
-Containing Neurons of Substantia Nigra https://www.mdpi.com/2076-2607/10/3/599/htm
Picornavirus May Be Linked to Parkinson’s Disease through Viral Antigen in
-Containing Neurons of Substantia Nigra https://www.mdpi.com/2076-2607/10/3/599/htm
Hidden
in
Cure Parkinson's
2 years ago
A Wise Person Told Me to Not Forget About TUDCA
Lastly, a rotenone-induced PD model using rats with daily intraperitoneal injections of UDCA resolved striatal
dopamine
content close to the control group level and significantly downregulated nuclear factor-κB (NF-κB), BCL2 associated X apoptosis regulator (Bax) and caspase-9 mRNA levels.
Lastly, a rotenone-induced PD model using rats with daily intraperitoneal injections of UDCA resolved striatal
dopamine
content close to the control group level and significantly downregulated nuclear factor-κB (NF-κB), BCL2 associated X apoptosis regulator (Bax) and caspase-9 mRNA levels.
Bolt_Upright
in
Cure Parkinson's
2 years ago
Sex drive
A year ago I got put on a
dopamine
medicine for restless legs syndrome. Side effects are possible addictive behaviour, risky behaviour, vivid dreams, ect. I was dreaming that she was cheating on me, but I was finding this to be a turn on.
A year ago I got put on a
dopamine
medicine for restless legs syndrome. Side effects are possible addictive behaviour, risky behaviour, vivid dreams, ect. I was dreaming that she was cheating on me, but I was finding this to be a turn on.
Gil89
in
Men's Health Forum
2 years ago
Lower lip
This is very uncomfortable, I have to pull lip down to talk, another low
dopamine
symptoms, I'm guessing. Anyone have botox in face from Parkinsons symptoms? Thank you all for your advice, Maria
This is very uncomfortable, I have to pull lip down to talk, another low
dopamine
symptoms, I'm guessing. Anyone have botox in face from Parkinsons symptoms? Thank you all for your advice, Maria
akgirlsrock
in
Cure Parkinson's
2 years ago
Anavex Life Sciences Announces Presentation of Phase 2 Clinical Biomarker Data from ANAVEX®2-73-PDD-001 Parkinson’s Disease Dementia Study
Study participants were allowed to be on stable regimen of anti-Parkinson's disease medications (including levodopa,
dopamine
agonists, MAO-B inhibitors, or entacapone).
Study participants were allowed to be on stable regimen of anti-Parkinson's disease medications (including levodopa,
dopamine
agonists, MAO-B inhibitors, or entacapone).
John_morris71
in
Cure Parkinson's
2 years ago
Dopamine Patch versus tablets your experience?
Hi, I am seeking your experience as to whether Patches are safe and do or do not cause more complications than the tablets. I was diagnosed with PD 6 years ago and my Neurologist has suggested a Neupro patch 2mg/24h because I reported no real on and off periods on the Madopar tablets and no real difference
Hi, I am seeking your experience as to whether Patches are safe and do or do not cause more complications than the tablets. I was diagnosed with PD 6 years ago and my Neurologist has suggested a Neupro patch 2mg/24h because I reported no real on and off periods on the Madopar tablets and no real difference
Coling
in
Cure Parkinson's
2 years ago
Dopamine Vs long term pain
Or any greater knowledge on the treatment of long term pain via
dopamine
regulation.
Or any greater knowledge on the treatment of long term pain via
dopamine
regulation.
Labrat80
in
Pain Concern
2 years ago
Recording now available of presentation by Prof Barker - Cambridge University: "Can we repair the brain in PD using cell-based therapies?"
We were all treated to an amazing presentation by Professor Roger Barker, explaining in great depth and with simplicity the journey so far and future hopes of cell-based
dopamine
replacement therapies.
We were all treated to an amazing presentation by Professor Roger Barker, explaining in great depth and with simplicity the journey so far and future hopes of cell-based
dopamine
replacement therapies.
Michel0220
in
Cure Parkinson's
2 years ago
Instant help
When I am in bed trying to sleep and my legs are jumping because my
dopamine
agonist doesn’t work, then I stand on my cold balcony only in my underwear for about 5 minutes (at the moment it is maybe about 0 and 8 degree Celsius or 32 to 46 degree Fahrenheit).
When I am in bed trying to sleep and my legs are jumping because my
dopamine
agonist doesn’t work, then I stand on my cold balcony only in my underwear for about 5 minutes (at the moment it is maybe about 0 and 8 degree Celsius or 32 to 46 degree Fahrenheit).
Happyfriday123
in
Restless Legs Syndrome
2 years ago
How can I get some real relief from this RLS torture?
Apart of course from
Dopamine
Agonists which I won't touch. Apologies for the length of my rant but, as you can probably tell, I am truly desperate (and miserable). 😭
Apart of course from
Dopamine
Agonists which I won't touch. Apologies for the length of my rant but, as you can probably tell, I am truly desperate (and miserable). 😭
feetgrind
in
Restless Legs Syndrome
2 years ago
Mirapex detox by microdosing?
Has anyone tried having a compounding pharmacy make the pills into microdoses and reducing extremely slowly so your brain has an easier time catching up with
dopamine
production? This seems like a gentler way of detoxing, but is there something I should be aware of? I'd appreciate any advice.
Has anyone tried having a compounding pharmacy make the pills into microdoses and reducing extremely slowly so your brain has an easier time catching up with
dopamine
production? This seems like a gentler way of detoxing, but is there something I should be aware of? I'd appreciate any advice.
bardo71
in
Restless Legs Syndrome
2 years ago
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