Experiences with

Dopamine

I read on a facebook page, "over 70% of our dopamine is produced in our gut and transported to the brain via the vagus nerve"? Does this mean all dopamine in the gut makes it to the vagus nerve--Even what is produced when bacteria consume our meds.

An estimated 85% to 90 % of patients with RLS will respond very well to opiates.An analysis of drug responses in RLS over a 2 to 10 year period showed that 85 percent of RLS patients who started on methadone were still on it compared to less than 20 percent of those who started on a Dopamine drug.

“Our experiments showed that farnesol both [i]significantly prevented the loss of neurons and reversed behavioral deficits[/i] in mice, indicating its promise as a potential drug treatment to prevent Parkinson’s disease,” Ted Dawson, MD, PhD, director of the Johns Hopkins Institute for

Interesting, i also took a supplement to increase dopamine shortly before all of this in conjunction with the vaping to improve performance in gym etc Anyone any have thoughts/comments? Could a dopamine supplement kick start RLS ? Kindest Regards

Question: is it likely that my dopamine receptors are damaged from the months on ropinerole? Another question: should I start taking berberine to help get them back to normal? Third question: regarding iron, I’m taking heme iron capsules every other night.

“[…] BTBD9 was observed to significantly reduce brain dopamine levels and led to an abnormal sleep pattern in mutant flies (182).

I thought it'd be worthwhile to try MP, I have got Now dopa mucuna 800 mg with 15% L- dopamine. Yesterday I took it at night I felt better. But tonight it's a different story. My legs feel like jelly and I Can't even sleep or move. Think I'm overdosed n having dyskinesia. My questions: 1.

It doesn't look at endogenous (locally produced) dopamine. John

Things are bad but there is no certain evidence this will occur.The process is him getting wired from release of dopamine etc. Sometimes I feel he is not making good decisions about purchases.Any advice is welcome. He is pushing me away.Unrealistic expections

Some of the available literature suggest that this supplement increase the dopamine levels https://lifespa.com/health-topics/energy/researchers-rediscover-shilajit-benefits/

“They don’t produce dopamine, but they may reduce the effects of whatever is causing the loss of dopamine,” he says. The higher the exercise intensity, the greater the levels of neurotrophic factors, Alberts adds.

They may be seen in autoimmune disorders triggered by an infectious or toxic agent, as in basal ganglia encephalitis with antibodies against the dopamine-D2 receptors. Is Parkinson's disease really a deficiency of dopamine or is it an inability to utilize the dopamine hormone?

In plain language this means that it stimulates the growth of new dopamine neurons. is stimulated. New studies show that ibogaine is also interesting for the treatment of Parkinson's patients.

An idle thought - could stimulants, specifically dopamine reuptake inhibitors (like Ritalin, Adderall, Vyvanse) treat the symptoms of RLS? Intuitively I would think yes, given that dopamine agonists are widely used for RLS.

The team has ‘programmed’ the cells to develop into dopamine nerve cell, which will be transplanted into the brains of patients to replace cells that are lost in Parkinson’s disease.

As a treatment, if it works, it would mean creating a small amount of stress to reduce dopamine levels. Perhaps it could be something as simple as putting your fingers in a bowl of iced water. I would appreciate some guidance as to the ethics of this approach.

known as 'seeding', prion-like proteins such as alpha Synuclein,  propagate their misfolded configuration by transforming their respective soluble monomers into fibrils. 1  Parkinson's disease (PD) is characterized by the presence of alpha Synuclein inclusions in the brain and the degeneration of dopamine-producing

I play a lot of solitaire on my phone and tablet because it's an easy source of dopamine when I'm struggling, and it provides enough of a boost to keep me going and eventually get back to what I had been trying to do. But it's also come with its fair share of frustrations.

Clonazepam but even taking a good mixture of meds nothing helped .I was waiting to get over the first couple of months hoping things would settle down but they never did unfortunately in my case I gave it a full year then couldn't take it any longer so went onto Neupro patch which I know is another Dopamine

Is it heat/ dopamine? Not sure - I’ll see how I go - interesting!