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Docetaxel
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Genetic Pathology Report is in, now what?
Before we discuss with MO (who replies the findings indicate continuation of SOC (
Docetaxel
+ Carboplatin), the key oncogenic markers are: ERBB3 (2.3%), MYC (2.7%), AGO2 (2.7), AR (5.8), TP53 (-4.0%). btw. NKX3-1 (16%) any suggestions on the way to go next?
Before we discuss with MO (who replies the findings indicate continuation of SOC (
Docetaxel
+ Carboplatin), the key oncogenic markers are: ERBB3 (2.3%), MYC (2.7%), AGO2 (2.7), AR (5.8), TP53 (-4.0%). btw. NKX3-1 (16%) any suggestions on the way to go next?
julyturqsee
in
Advanced Prostate Cancer
3 years ago
Not responding
With the
Docetaxel
his psa just keeps going up. He just had his fourth round. Spoke with his local oncologist yesterday. He said if someone doesn’t respond to
Docetaxel
it ususally is a poor prognosis. I have not yet heard from Dana Farber Dr Beltran. I want to see if she feels the same.
With the
Docetaxel
his psa just keeps going up. He just had his fourth round. Spoke with his local oncologist yesterday. He said if someone doesn’t respond to
Docetaxel
it ususally is a poor prognosis. I have not yet heard from Dana Farber Dr Beltran. I want to see if she feels the same.
Fight11
in
Advanced Prostate Cancer
3 years ago
Ice on hands/feet during taxotere/docetaxel infusion: what for and does it work
I am having my second infusion in a week. From the first infusion I got some pain in my wrists and feet, especially when cold. Not sure if it is arthritis. Also food doesn't taste the same anymore. I've read that using ice during infusion can mitigate these effects. Googling helped, but I would like
I am having my second infusion in a week. From the first infusion I got some pain in my wrists and feet, especially when cold. Not sure if it is arthritis. Also food doesn't taste the same anymore. I've read that using ice during infusion can mitigate these effects. Googling helped, but I would like
Oldie68
in
Advanced Prostate Cancer
2 years ago
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Docetaxel
He is now on
Docetaxel
he had his fourth round today. Psa does not seem to be responding. He will have bone scans and ct scan.Is there something he can take in conjunction with the chemo? If this treatment fails I don’t know where to go from here.
He is now on
Docetaxel
he had his fourth round today. Psa does not seem to be responding. He will have bone scans and ct scan.Is there something he can take in conjunction with the chemo? If this treatment fails I don’t know where to go from here.
Fight11
in
Advanced Prostate Cancer
3 years ago
Experiencing Leg muscle weakness post chemo, not able to walk more than 2-3 mins, any advice?
Completed 10
docetaxel
session on 19th October. After 9th chemo I experienced left leg muscle getting tired only after 2-3 mins of walk and I needed to sit. On doctor's advice started pregabalin 75 twice daily from 12th October. Got back to normalcy after 2 days. Stopped med on 15th November.
Completed 10
docetaxel
session on 19th October. After 9th chemo I experienced left leg muscle getting tired only after 2-3 mins of walk and I needed to sit. On doctor's advice started pregabalin 75 twice daily from 12th October. Got back to normalcy after 2 days. Stopped med on 15th November.
Soumen79
in
Advanced Prostate Cancer
3 years ago
Chemo induced anemia
My father has had 2 cycles of
docetaxel
chemo and his Hb is 8.2 g/dl while RBC is 2.96 mcL. Due to this, the next chemo has been postponed by a week The MO says the only way anemia can be dealt is blood transfusion if Hb goes below 8 g/dl.
My father has had 2 cycles of
docetaxel
chemo and his Hb is 8.2 g/dl while RBC is 2.96 mcL. Due to this, the next chemo has been postponed by a week The MO says the only way anemia can be dealt is blood transfusion if Hb goes below 8 g/dl.
Vsahay
in
Advanced Prostate Cancer
3 years ago
Lymphoedema with MBC
I am currently halfway through my chemo - I have had three cycles of
Docetaxel
(plus Phesgo) with three to go. I've had a lot of horrible side-effects but am persevering.
I am currently halfway through my chemo - I have had three cycles of
Docetaxel
(plus Phesgo) with three to go. I've had a lot of horrible side-effects but am persevering.
Ursula_I
in
SHARE Metastatic Breast Cancer
3 years ago
Trial: Docetaxel in combination with DKN-01
Has any one had experience with this form of therapy with DKN-01 monoclonal antibody and
Docetaxel
to treat advance PCa patients with elevated DKK1?
Has any one had experience with this form of therapy with DKN-01 monoclonal antibody and
Docetaxel
to treat advance PCa patients with elevated DKK1?
Back2future
in
Advanced Prostate Cancer
3 years ago
Clinical trial
He was suppose to start his chemo tomorrow the new one seen as though the
Docetaxel
failed. Now our concern is he will not be able to start the chemo if we go with the trial which means he will be on no treatment for a month. His cancer will spread. He is already having pain.
He was suppose to start his chemo tomorrow the new one seen as though the
Docetaxel
failed. Now our concern is he will not be able to start the chemo if we go with the trial which means he will be on no treatment for a month. His cancer will spread. He is already having pain.
Fight11
in
Advanced Prostate Cancer
3 years ago
Intermittant chemo
I am going to ask him about doing more chemo (
Docetaxel
) in intermittant sessions - for example one session every 4 months. Havnt found too much literature on that yet (more on other cancers) - am going to ask what he thinks.
I am going to ask him about doing more chemo (
Docetaxel
) in intermittant sessions - for example one session every 4 months. Havnt found too much literature on that yet (more on other cancers) - am going to ask what he thinks.
Stoneartist
in
Advanced Prostate Cancer
3 years ago
information on BITE trial: anyone have experience with BITE?
it seems my partner is losing ground fast on Standard Care Lupron + (Zytiga failed in less than 8 months); he's on Chemo (
Docetaxel
(the first 4 failed out of 7 infusions) + Carboplatin (3).
it seems my partner is losing ground fast on Standard Care Lupron + (Zytiga failed in less than 8 months); he's on Chemo (
Docetaxel
(the first 4 failed out of 7 infusions) + Carboplatin (3).
julyturqsee
in
Advanced Prostate Cancer
3 years ago
Experiences with Docetaxel after lots of side effects from first session
Hi, I had my first
Docetaxel
session 12 days ago and it's been a rough ride. Severe joint pain (solved with hydromorphone), nausea, constipation and now an infection. I'm wondering what the future sessions may bring.
Hi, I had my first
Docetaxel
session 12 days ago and it's been a rough ride. Severe joint pain (solved with hydromorphone), nausea, constipation and now an infection. I'm wondering what the future sessions may bring.
davebliz
in
Advanced Prostate Cancer
3 years ago
What kind timeline are we looking at?
Past Treatment: -
Docetaxel
x 6 cycles 12/29/2015- 4/15/2016 - Xtandi 9/2/2018- 9/2019 - Apalutamide 1/15/2020- June 2020 - Olaparib 150 mg PO BID started on 8/20/2020, dose reduced to 75 mg PO BID on 10/13/2020, discontinued due to side effects on 06/29/2021 - palliative RT to prostate and inferior
Past Treatment: -
Docetaxel
x 6 cycles 12/29/2015- 4/15/2016 - Xtandi 9/2/2018- 9/2019 - Apalutamide 1/15/2020- June 2020 - Olaparib 150 mg PO BID started on 8/20/2020, dose reduced to 75 mg PO BID on 10/13/2020, discontinued due to side effects on 06/29/2021 - palliative RT to prostate and inferior
KinkyPinky
in
Advanced Prostate Cancer
3 years ago
Dasatinib
therapy after discontinuing
docetaxel
treatment."
therapy after discontinuing
docetaxel
treatment."
pjoshea13
in
Advanced Prostate Cancer
3 years ago
177Lu-PSMA-617 versus docetaxel in chemotherapy-naïve mCRPC: a randomized, controlled, phase 2 non inferiority trial.
/134156-177lu-psma-617-versus-
docetaxel
-in-chemotherapy-naive-metastatic-castration-resistant-prostate-cancer-a-randomized-controlled-phase-2-non-inferiority-trial.html
/134156-177lu-psma-617-versus-
docetaxel
-in-chemotherapy-naive-metastatic-castration-resistant-prostate-cancer-a-randomized-controlled-phase-2-non-inferiority-trial.html
tango65
in
Advanced Prostate Cancer
3 years ago
Some good news!!
A quick recap: DX PCa, gleason4+5 jan 2000 with PSA=1000, started Zoladex and
docetaxel
(6 sessions)immediately, PSA steadily falling til july 2021 when castrate resistance kicked in. Starten on Xtandi 6 Okt with PSA at 4.7. Todays news is great.
A quick recap: DX PCa, gleason4+5 jan 2000 with PSA=1000, started Zoladex and
docetaxel
(6 sessions)immediately, PSA steadily falling til july 2021 when castrate resistance kicked in. Starten on Xtandi 6 Okt with PSA at 4.7. Todays news is great.
Stoneartist
in
Advanced Prostate Cancer
3 years ago
Eyelid swelling with docetaxel
Has anyone experienced swelling of upper eyelid during chemo? My father had his 2nd chemo 2 days ago and now has left upper eyelid swelling with mild pain
Has anyone experienced swelling of upper eyelid during chemo? My father had his 2nd chemo 2 days ago and now has left upper eyelid swelling with mild pain
Vsahay
in
Advanced Prostate Cancer
3 years ago
Appointment with Oncologist tomorrow what should we ask about Docetaxel?
Husband has 6th Xofigo on this Thursday. PSA when started in June was 447.53 July it went down 354.52. We knew PSA was not important during these months but Oct it was 692.39.Oncologist called and thinks it is time to try Chemo. My husband who has wanted to try to maintain quality of life is willing
Husband has 6th Xofigo on this Thursday. PSA when started in June was 447.53 July it went down 354.52. We knew PSA was not important during these months but Oct it was 692.39.Oncologist called and thinks it is time to try Chemo. My husband who has wanted to try to maintain quality of life is willing
Yorkielover2
in
Advanced Prostate Cancer
3 years ago
Low Red Blood Cell count
I had initially started on
Docetaxel
about 19 months ago and had three treatments. So maybe bone marrow was impacted somewhat then.
I had initially started on
Docetaxel
about 19 months ago and had three treatments. So maybe bone marrow was impacted somewhat then.
tennis8285
in
Advanced Prostate Cancer
3 years ago
Rising PSA after chemo, next steps?
Started degarelix, had 6 sessions of
docetaxel
, added abiraterone in August, consolidative SBRT in September. Lowest PSA was 0.99 right after chemo, in August. In September, 1.12, October 1.87, and now in November it is 4.16. His Testosterone levels remain <7. (Switched to Orgovyx 6 weeks ago.)
Started degarelix, had 6 sessions of
docetaxel
, added abiraterone in August, consolidative SBRT in September. Lowest PSA was 0.99 right after chemo, in August. In September, 1.12, October 1.87, and now in November it is 4.16. His Testosterone levels remain <7. (Switched to Orgovyx 6 weeks ago.)
leebeth
in
Advanced Prostate Cancer
3 years ago
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