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Perineural invasion increases soft tissue progression risk in metastatic castration-resistant prostate cancer post-abiraterone resistance
Background : Prostate cancer presents with soft tissue progression (STP) is highly aggressive. We analyzed the risk factor for STP in patients with metastatic castration-resistant prostate cancer (mCRPC) who developed abiraterone acetate (AA) resistance. Methods : This retrospective study included
Background : Prostate cancer presents with soft tissue progression (STP) is highly aggressive. We analyzed the risk factor for STP in patients with metastatic castration-resistant prostate cancer (mCRPC) who developed abiraterone acetate (AA) resistance. Methods : This retrospective study included
God_Loves_Me
in
Advanced Prostate Cancer
3 months ago
Cholesterol Issues Question
Hi, I recently had a routine physical (first time in a few years) and my cholesterol was through the roof LDL 188 Overall 260 I had a few questions as I am in full panic mode. 1) I had a few beers the night before the test and buffalo chicken pizza (11 hours before test) following a week of hot
Hi, I recently had a routine physical (first time in a few years) and my cholesterol was through the roof LDL 188 Overall 260 I had a few questions as I am in full panic mode. 1) I had a few beers the night before the test and buffalo chicken pizza (11 hours before test) following a week of hot
Bostonj
in
Anxiety Support
1 month ago
Divver? IBS? Something more sinister?
Back again. Noticed after a few weeks that I was eating fairly normally - always very careful - and not really going to the bathroom as much as I should have. Small soft BMs, after feeling like a huge BM was coming. Also having either hemmerhoid or fissure, fistula issues, but my opening is very sore
Back again. Noticed after a few weeks that I was eating fairly normally - always very careful - and not really going to the bathroom as much as I should have. Small soft BMs, after feeling like a huge BM was coming. Also having either hemmerhoid or fissure, fistula issues, but my opening is very sore
NewEnglander
in
IBS Network
10 months ago
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worries
Here again. I am just so worried still. My liver enzymes were high. Managed to stay off the booze. Alt gone down slightly but ggt gone up a lot. Iron is low. My g p keeps saying it’s mental health issues but surely that cannot make my bloods deranged. She did an e consult to hepology and he said I
Here again. I am just so worried still. My liver enzymes were high. Managed to stay off the booze. Alt gone down slightly but ggt gone up a lot. Iron is low. My g p keeps saying it’s mental health issues but surely that cannot make my bloods deranged. She did an e consult to hepology and he said I
Curryblue
in
British Liver Trust
3 months ago
Heart Palps after eating
Does anyone get Heart palpitations after eating ? I get them no matter what I eat protein only, prot & carbs or carbs (tested this) … This isn’t new but its becoming more pronounced and I can’t figure out the issues or if it’s hypo related but just seems odd to hit only after eating (morning) is the
Does anyone get Heart palpitations after eating ? I get them no matter what I eat protein only, prot & carbs or carbs (tested this) … This isn’t new but its becoming more pronounced and I can’t figure out the issues or if it’s hypo related but just seems odd to hit only after eating (morning) is the
Batty1
in
Thyroid UK
5 months ago
Australian research - possible cure?
I don’t like raising false hope among our community about ‘cures’ toted in the media, but I found this article interesting. It’s about the T-cells, which many of us already know is involved in autoimmune activity: https://www.sbs.com.au/news/podcast-episode/australian-researchers-develop-world-first-method-of-treating-lupus
I don’t like raising false hope among our community about ‘cures’ toted in the media, but I found this article interesting. It’s about the T-cells, which many of us already know is involved in autoimmune activity: https://www.sbs.com.au/news/podcast-episode/australian-researchers-develop-world-first-method-of-treating-lupus
MusicalFurbaby
in
LUPUS UK
6 months ago
What happens next
My 68 year old husband was diagnosed with metastatic prostate cancer to the bones Oct 22 with PSA at 220. Since then he has been on Zoladex, Enzalutamide and has just finished 8 rounds of Docetaxel. Apart from this cancer he is very healthy - but what happens now when the PSA starts rising again. He
My 68 year old husband was diagnosed with metastatic prostate cancer to the bones Oct 22 with PSA at 220. Since then he has been on Zoladex, Enzalutamide and has just finished 8 rounds of Docetaxel. Apart from this cancer he is very healthy - but what happens now when the PSA starts rising again. He
Bongoed
in
Advanced Prostate Cancer
3 months ago
Apixaban
I wonder if there is anyone here who is over 80, weighs less than 55kg and is on Apixaban? I was on warfarin but due to my INR being very unstable and also my forgetting to take it sometimes, my cardiologist switched me to Apixaban which I found a great improvement in that there were no more diet restrictions
I wonder if there is anyone here who is over 80, weighs less than 55kg and is on Apixaban? I was on warfarin but due to my INR being very unstable and also my forgetting to take it sometimes, my cardiologist switched me to Apixaban which I found a great improvement in that there were no more diet restrictions
Greenhilldrive
in
Anticoagulation Support
5 months ago
I am waiting to find out if I have Lupus but I haven’t got my ANA result back yet and I want to know if people think this could be lupus
Hi, I have been having concerns for over a year about me having Lupus. I had a blood test last year which everything came back normal and the ANA was negative however I am experiencing more symptoms this year and I have taken another blood test and so far the bloods again are normal but I have currently
Hi, I have been having concerns for over a year about me having Lupus. I had a blood test last year which everything came back normal and the ANA was negative however I am experiencing more symptoms this year and I have taken another blood test and so far the bloods again are normal but I have currently
katiepops2004
in
LUPUS UK
6 months ago
Please advise about treatment
I posted recently about my Dad’s PSA going up from 0.008 in December 2023 to 0.029 in March 2024. He had a PET Scan that showed some activity in a rib and prostate, MRI showed nothing. The PSA started dropping to 0.026 at the end of March and then 0.025 in April without any treatment. We didn’t anticipate
I posted recently about my Dad’s PSA going up from 0.008 in December 2023 to 0.029 in March 2024. He had a PET Scan that showed some activity in a rib and prostate, MRI showed nothing. The PSA started dropping to 0.026 at the end of March and then 0.025 in April without any treatment. We didn’t anticipate
Simonapo
in
Advanced Prostate Cancer
3 months ago
Three Big Challenges in Metastatic PC
Common themes that often emerge from the posts and responses on this particular hub of HU are intermittent and alternative therapy, the use of testosterone replacement and the various associated issues. In the latest GU podcast, co-hosts Dr Declan Murphy and Renu Eapen from [i]Peter MacCallum Cancer
Common themes that often emerge from the posts and responses on this particular hub of HU are intermittent and alternative therapy, the use of testosterone replacement and the various associated issues. In the latest GU podcast, co-hosts Dr Declan Murphy and Renu Eapen from [i]Peter MacCallum Cancer
marnieg46
in
Fight Prostate Cancer
3 months ago
Caffeine shown to affect brain dopamine function in patients with Parkinson's disease
Regular high caffeine consumption affects dopamine function in patients with Parkinson's disease, shows a new international study led by the University of Turku and Turku University Hospital in Finland. Caffeine consumption before undergoing diagnostic brain dopamine imaging may also affect the imaging
Regular high caffeine consumption affects dopamine function in patients with Parkinson's disease, shows a new international study led by the University of Turku and Turku University Hospital in Finland. Caffeine consumption before undergoing diagnostic brain dopamine imaging may also affect the imaging
JCRO
in
Cure Parkinson's
3 months ago
pulsatile tinnitus
hi I’ve had pulsatile tinnitus for almost 2 years. It came on all of a sudden not long after I’d had covid and had been a bit unwell with migraine for a week or so. A nurse said I had an ear infection but antibiotics made no difference. I was quickly sent for an MRA which was clear. I also had an ENT
hi I’ve had pulsatile tinnitus for almost 2 years. It came on all of a sudden not long after I’d had covid and had been a bit unwell with migraine for a week or so. A nurse said I had an ear infection but antibiotics made no difference. I was quickly sent for an MRA which was clear. I also had an ENT
Pinkbarbi
in
Tinnitus UK
5 months ago
PSA test after TRUS Biopsy ?
Would a trus biopsy affect psa results. How many days after a biopsy can one get a psa done doc has said to get biopsy done and then meet him with biopsy results and a fresh psa even though psa was done 3 weeks back and was 18
Would a trus biopsy affect psa results. How many days after a biopsy can one get a psa done doc has said to get biopsy done and then meet him with biopsy results and a fresh psa even though psa was done 3 weeks back and was 18
Tinkudi
in
Advanced Prostate Cancer
3 months ago
tinnitus on rapid head rotation
Does anyone else experience a sound/vibration when shaking their head quickly from side to side? What I hear is a vibration of frequency about E flat (about 610Hz)? I have recently had an attempt at micro suction to remove ear wax and this has only started since then and I am wondering whether there
Does anyone else experience a sound/vibration when shaking their head quickly from side to side? What I hear is a vibration of frequency about E flat (about 610Hz)? I have recently had an attempt at micro suction to remove ear wax and this has only started since then and I am wondering whether there
SandraMarric
in
Tinnitus UK
5 months ago
Orgovyx and Zytiga with adding Prozac, good or bad?
Poollover wants to know if adding Prozac would cause a problem with androgen deprivation drugs?
Poollover wants to know if adding Prozac would cause a problem with androgen deprivation drugs?
Poollover
in
Advanced Prostate Cancer
5 months ago
After 25 years they have stopped my B12 - what can I do?
I'm in my early sixties. Generally very good health. On no medication. About twenty five years ago my then brilliant GP did a blood test for B12. A few days later rang me to come to the surgery immediately where he injected B12 himself. Apparently I had dangerously low levels of B12 that indicated I
I'm in my early sixties. Generally very good health. On no medication. About twenty five years ago my then brilliant GP did a blood test for B12. A few days later rang me to come to the surgery immediately where he injected B12 himself. Apparently I had dangerously low levels of B12 that indicated I
DIYenthusiast
in
Pernicious Anaemia Society
1 day ago
Health anxiety
I m having health anxiety since 15 years. I lost my very precious 15 years almost sitting in one corner. It's very difficult to write everything at once. Pls any one here help.I m under medication Daxid 100mg - 2 tablets per day ( sertraline) Clonotril 2mg - 2 tablets per day (Clonazapam) One glucose
I m having health anxiety since 15 years. I lost my very precious 15 years almost sitting in one corner. It's very difficult to write everything at once. Pls any one here help.I m under medication Daxid 100mg - 2 tablets per day ( sertraline) Clonotril 2mg - 2 tablets per day (Clonazapam) One glucose
Blackandwhite1
in
Anxiety Support
1 month ago
Help!
I'm at the end of my tether. I'm 74 and have had UTIs since 16 - usually 1-2 a year, easily treated. A couple of years ago they were getting more frequent and GP gave me standby px for Macrobid and with this I've managed to self treat at the 1st symptom. 5 months ago I had a bad flare up which took several
I'm at the end of my tether. I'm 74 and have had UTIs since 16 - usually 1-2 a year, easily treated. A couple of years ago they were getting more frequent and GP gave me standby px for Macrobid and with this I've managed to self treat at the 1st symptom. 5 months ago I had a bad flare up which took several
Lunadoo
in
Bladder Health UK
5 months ago
Thanks for letting me join
I found out today I have to have injections into my right eye for macular, left eye is dry macular. not sure what’s happening on that one, I’m absolutely petrified, I didn’t ask any questions as I was too scared, I just wanted to get out. Can anyone tell me what will happen please. I had both cataracts
I found out today I have to have injections into my right eye for macular, left eye is dry macular. not sure what’s happening on that one, I’m absolutely petrified, I didn’t ask any questions as I was too scared, I just wanted to get out. Can anyone tell me what will happen please. I had both cataracts
marysuds
in
Macular Society
5 months ago
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