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Clinical Trials
Has anyone participated in ANY Clinical Trials?? Which ones and have they helped at all???
Has anyone participated in ANY Clinical Trials?? Which ones and have they helped at all???
smv123
in
Cure Parkinson's
8 months ago
Vitamin D and Dementia
Vitamin D is a topic that gets a regular airing on this forum. In the context of CLL, here is a good place to review past posts https://healthunlocked.com/cllsupport/posts/149126536/recent-research-report?responses=149129259 (reply by Lankisterguy). Personally, the idea of dying with CLL just doesn't
Vitamin D is a topic that gets a regular airing on this forum. In the context of CLL, here is a good place to review past posts https://healthunlocked.com/cllsupport/posts/149126536/recent-research-report?responses=149129259 (reply by Lankisterguy). Personally, the idea of dying with CLL just doesn't
bennevisplace
in
CLL Support
8 months ago
Easy-to-use inhaled levodopa system readying request for US approval
That’s according to results from a company-sponsored clinical trial (NCT06037590) comparing the pharmacological properties of Levodopa Cyclops against those of Inbrija, an approved inhaled powder formulation of levodopa developed by Acorda Therapeutics. “This randomized cross-over trial of Levodopa
That’s according to results from a company-sponsored clinical trial (NCT06037590) comparing the pharmacological properties of Levodopa Cyclops against those of Inbrija, an approved inhaled powder formulation of levodopa developed by Acorda Therapeutics. “This randomized cross-over trial of Levodopa
Farooqji
in
Cure Parkinson's
8 months ago
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clinical trial: ATR inhibitor for ATM mutated solid tumors
in vivo and in vitro studies suggest that ATR inhibitors work better than PARP inhibitors for people with ATM gene mutations…but together they may work even better I hope to find more data about this clinical trial https://www.biospace.com/article/releases/aprea-therapeutics-announces-dosing-of-first-patient-in-phase
in vivo and in vitro studies suggest that ATR inhibitors work better than PARP inhibitors for people with ATM gene mutations…but together they may work even better I hope to find more data about this clinical trial https://www.biospace.com/article/releases/aprea-therapeutics-announces-dosing-of-first-patient-in-phase
Maxone73
in
Advanced Prostate Cancer
8 months ago
lung hyperinflation,
Having severe shortness of breath month now, chest xray shows moderate lung hyperinflation. Can this be caused by anxiety?
Having severe shortness of breath month now, chest xray shows moderate lung hyperinflation. Can this be caused by anxiety?
msthingy123
in
Lung Conditions Community Forum
1 year ago
Current SUPERNOVA Clinical Trial for Reformulated EVUSHELD for preventing COVID-19 infection for immune-impaired individuals
A Phase II sub-study of SUPERNOVA clinical trial (2023) is currently operating to test the efficacy and safety of AZD3152 as a component of a reformulated version of EVUSHELD mAbs prophylaxis for immune-impaired individuals who cannot mount antibody responses to COVID-19 vaccines. Study Understanding
A Phase II sub-study of SUPERNOVA clinical trial (2023) is currently operating to test the efficacy and safety of AZD3152 as a component of a reformulated version of EVUSHELD mAbs prophylaxis for immune-impaired individuals who cannot mount antibody responses to COVID-19 vaccines. Study Understanding
Classicaljazz
in
CLL Support
8 months ago
need some guidance, feeling desperate..
My husband has advanced, Stage IV castration resistant prostate cancer. When he was diagnosed in May 2022 his PSA was 4700, he has widespread bone metastases. He stopped responding to Docetaxel, Pluvicto and is now not responding to Cabazitaxel, his PSA is now over 700. He is feeling good, no pain
My husband has advanced, Stage IV castration resistant prostate cancer. When he was diagnosed in May 2022 his PSA was 4700, he has widespread bone metastases. He stopped responding to Docetaxel, Pluvicto and is now not responding to Cabazitaxel, his PSA is now over 700. He is feeling good, no pain
Kiki27
in
Advanced Prostate Cancer
8 months ago
Taste Issues and finger neuropathy on Xtandi( enzalutamide) ?
In order to participate in a clinical trial (FOR46 at UCSF) I had to switch from Nubeqa (darolutamide) to enzalutamide. Previously on abiraterone. Did really well on both medications. Now 4 months on enzalutamide and my 5th research infusion, I'm experiencing some side effects. Trying to determine
In order to participate in a clinical trial (FOR46 at UCSF) I had to switch from Nubeqa (darolutamide) to enzalutamide. Previously on abiraterone. Did really well on both medications. Now 4 months on enzalutamide and my 5th research infusion, I'm experiencing some side effects. Trying to determine
bandgeek
in
Advanced Prostate Cancer
8 months ago
It won't end!
I have been plagued with severe depression and mercilessly suffering with both depression andi anxiety since 2021.I've been in and out of the hospital. I feel hopeless and don't want to go on.
I have been plagued with severe depression and mercilessly suffering with both depression andi anxiety since 2021.I've been in and out of the hospital. I feel hopeless and don't want to go on.
Notthesamecat
in
Anxiety and Depression Support
1 year ago
Randomised clinical trial - prophylactic radiation therapy to asymptomatic bone metastases improved survival
Prophylactic Radiation Therapy Versus Standard of Care for Patients With High-Risk Asymptomatic Bone Metastases: A Multicenter, Randomized Phase II Clinical Trial Authors: Erin F. Gillespie, MD, MPH https://orcid.org/0000-0002-1386-1542 gillespe@mskcc.org, Joanna C. Yang, MD, MPH, Noah J. Mathis, BA
Prophylactic Radiation Therapy Versus Standard of Care for Patients With High-Risk Asymptomatic Bone Metastases: A Multicenter, Randomized Phase II Clinical Trial Authors: Erin F. Gillespie, MD, MPH https://orcid.org/0000-0002-1386-1542 gillespe@mskcc.org, Joanna C. Yang, MD, MPH, Noah J. Mathis, BA
Graham49
in
Advanced Prostate Cancer
9 months ago
Acalabrutinib and Skin Cancers
I began taking Acalabrutinib three years ago as a participant in a clinical trial. I have enjoyed excellent success. However, recently I began breaking out in skin cancer lesions on various parts of the body. Particularly on my legs, ankles and feet. I have been prone to sun damaged skin converting
I began taking Acalabrutinib three years ago as a participant in a clinical trial. I have enjoyed excellent success. However, recently I began breaking out in skin cancer lesions on various parts of the body. Particularly on my legs, ankles and feet. I have been prone to sun damaged skin converting
spanish36
in
CLL Support
9 months ago
Amitriptyline - ATLANTIS clinical trial
Can anyone explain to me why money has been spent on a clinical trial for amitriptyline in relation to IBS, when this has been prescribed for IBS and specifically IBS pain for years already?: https://www.theibsnetwork.org/blog/irritable-bowel-syndrome-relieved-by-low-dose-amitriptyline/ When investigating
Can anyone explain to me why money has been spent on a clinical trial for amitriptyline in relation to IBS, when this has been prescribed for IBS and specifically IBS pain for years already?: https://www.theibsnetwork.org/blog/irritable-bowel-syndrome-relieved-by-low-dose-amitriptyline/ When investigating
xjrs
in
IBS Network
9 months ago
Senolytics - “senolytic” drugs, dasatinib (D) and quercetin (Q) disapointing results in small test- Peter Attia
January 13, 2024 COGNITIVE HEALTH & NEURODEGENERATIVE DISEASE Targeting senescent cells for cognitive health With the recent publication of the first clinical trial of senolytics for AD treatment, popular interest in these drugs has swelled, but is the excitement justified? PETER ATTIA
January 13, 2024 COGNITIVE HEALTH & NEURODEGENERATIVE DISEASE Targeting senescent cells for cognitive health With the recent publication of the first clinical trial of senolytics for AD treatment, popular interest in these drugs has swelled, but is the excitement justified? PETER ATTIA
Scout4answers
in
Fight Prostate Cancer
9 months ago
High-Dose Vitamin B1 / Thiamine and Fat Soluble Benfotiamine Form
I am reposting a reply to the Vitamin B1 thread as I noticed a search on HealthUnlocked for Benfotiamine doesn't list the thread for Vitamin B1 and the information I posted doesn't fit in one reply. I'm not giving medical advice but I know a lot of people here are open to trying things and watch if
I am reposting a reply to the Vitamin B1 thread as I noticed a search on HealthUnlocked for Benfotiamine doesn't list the thread for Vitamin B1 and the information I posted doesn't fit in one reply. I'm not giving medical advice but I know a lot of people here are open to trying things and watch if
jazj
in
Advanced Prostate Cancer
9 months ago
anticipatory anxiety
tonight I am going to a concet. I’m not worried about getting sick as it is outdoors at a stadium. But concerts tend to make me a little nervous. Once I’m there I’m usually fine but it’s the anticipation. Also one of my friends may stay over my apartment. I’m close with her but we don’t see each other
tonight I am going to a concet. I’m not worried about getting sick as it is outdoors at a stadium. But concerts tend to make me a little nervous. Once I’m there I’m usually fine but it’s the anticipation. Also one of my friends may stay over my apartment. I’m close with her but we don’t see each other
Daisy425
in
Anxiety and Depression Support
1 year ago
SRBT and EXTEND trial
Does anybody have the full text of EXTEND trial results from June 2023? (my payment attempt is rejected and the tips on how to get a study without cost doesn´t work) https://pubmed.ncbi.nlm.nih.gov/37022702/ Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic
Does anybody have the full text of EXTEND trial results from June 2023? (my payment attempt is rejected and the tips on how to get a study without cost doesn´t work) https://pubmed.ncbi.nlm.nih.gov/37022702/ Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic
Purple-Bike
in
Advanced Prostate Cancer
9 months ago
New Malecare AI Assisted PCa Search
For users of the $20 per month ChatGPT account Malecare is the world's first patient advocacy organization to develop and publish GPT's in Open AI's Chat GPT (app) Marketplace! Indeed, we have five apps published! Here they are: Clinical Trial Navigator -- https://chat.openai.com/g/g-rl6cvjdon-clinical-trial-navigator
For users of the $20 per month ChatGPT account Malecare is the world's first patient advocacy organization to develop and publish GPT's in Open AI's Chat GPT (app) Marketplace! Indeed, we have five apps published! Here they are: Clinical Trial Navigator -- https://chat.openai.com/g/g-rl6cvjdon-clinical-trial-navigator
dmt1121
in
Advanced Prostate Cancer
9 months ago
Endless cycles
I was in therapy, and we talked about emotions and my problem with attempting to be vulnerable.I get frustrated and even if the initial problem is resolved, it lingers. Therapist states that it's because of a deeper emotion. All I can conclude is that I feel helpless. I do feel this way with a lot of
I was in therapy, and we talked about emotions and my problem with attempting to be vulnerable.I get frustrated and even if the initial problem is resolved, it lingers. Therapist states that it's because of a deeper emotion. All I can conclude is that I feel helpless. I do feel this way with a lot of
Gradients-of-Blue
in
Anxiety and Depression Support
1 year ago
Totally Exhausted lately due to ...
Hello I am in US and used to take 88 mcg Unithroid, and 30 MCG of Cytomel. Then the doctor discontinued my Cytomel. So I got some Grossman Cynomel from Mexico which works great. I have been on Cynomel for 3 months. I tested a month ago and had my Unithroid go down to 1.02 (range is .82 to 1.77
Hello I am in US and used to take 88 mcg Unithroid, and 30 MCG of Cytomel. Then the doctor discontinued my Cytomel. So I got some Grossman Cynomel from Mexico which works great. I have been on Cynomel for 3 months. I tested a month ago and had my Unithroid go down to 1.02 (range is .82 to 1.77
jeanie245
in
Thyroid UK
1 year ago
Experiences and Research on Managing PV with Autophagy, Intermittent Fasting, and Vegan Diet
Hello everyone, I am reaching out to the community for insights and personal experiences regarding the management of Polycythemia Vera (PV), particularly in relation to autophagy, intermittent fasting, and vegan diets. [u]
Autophagy and PV
[/u]: Has anyone with PV experimented with or has
Hello everyone, I am reaching out to the community for insights and personal experiences regarding the management of Polycythemia Vera (PV), particularly in relation to autophagy, intermittent fasting, and vegan diets. [u]
Autophagy and PV
[/u]: Has anyone with PV experimented with or has
skakulec2
in
MPN Voice
9 months ago
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