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Upcoming Hormone Therapy and Sex
Currently 52, diagnosed at 49 with Gleason 7 (3 +4) and PSA 5.1. Underwent prostatectomy (clear margins, lymph clean, seminal vesicle removed, but extraprostatic extensions) later followed by salvage radiation due to PSA recurrence. At this point my PSA has increased every three months from 0.11 to
Currently 52, diagnosed at 49 with Gleason 7 (3 +4) and PSA 5.1. Underwent prostatectomy (clear margins, lymph clean, seminal vesicle removed, but extraprostatic extensions) later followed by salvage radiation due to PSA recurrence. At this point my PSA has increased every three months from 0.11 to
OhioGuy2
in
Advanced Prostate Cancer
5 years ago
Adding Casodex (Bicalutamide) a good idea ?
I’d like to ask this community about the wisdom of adding Casodex to standard ADT. Background: Dx Feb 2018, PSA 168; multiple mets to bones. Firmagon monthly Feb - Nov switched to 3 monthly Dipherelin in Nov. 6 rounds of Docetaxel Apr - Jul. PSA nadir 0.4 in Aug. rose slightly to 0.64 by Mar 2019
I’d like to ask this community about the wisdom of adding Casodex to standard ADT. Background: Dx Feb 2018, PSA 168; multiple mets to bones. Firmagon monthly Feb - Nov switched to 3 monthly Dipherelin in Nov. 6 rounds of Docetaxel Apr - Jul. PSA nadir 0.4 in Aug. rose slightly to 0.64 by Mar 2019
hansjd
in
Advanced Prostate Cancer
5 years ago
Need more Info
Hola Fellow Travelers I am a 76 year old Canadian living in Mexico. In May of last year my PSA registered 128 ng/mL The four physicians that I consulted all assured me that I had prostate cancer which had almost certainly metastasized. My gammagram was negative for bone metastasis and since I have
Hola Fellow Travelers I am a 76 year old Canadian living in Mexico. In May of last year my PSA registered 128 ng/mL The four physicians that I consulted all assured me that I had prostate cancer which had almost certainly metastasized. My gammagram was negative for bone metastasis and since I have
Frigataflyer
in
Advanced Prostate Cancer
5 years ago
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My Story
It all started in October 2017 with a regular visit to my PCP for prescription refills. Once the check up was completed and I was leaving he called out to me and said "Hey, you're due for your annual blood work" sure I got some time and they drew the blood. 12 hours later I get the results online. Normal
It all started in October 2017 with a regular visit to my PCP for prescription refills. Once the check up was completed and I was leaving he called out to me and said "Hey, you're due for your annual blood work" sure I got some time and they drew the blood. 12 hours later I get the results online. Normal
Hidden
in
Advanced Prostate Cancer
5 years ago
Casodex dosing
Just got first shot of Lupron yesterday, I have been on casodex for 24 days so far . Got prescription from doctor who dx me . I asked RO how long should I be on it . He said I usually do 2 weeks of casodex before Lupron shot so I say I have another 40 pills left he says take them .... is more better
Just got first shot of Lupron yesterday, I have been on casodex for 24 days so far . Got prescription from doctor who dx me . I asked RO how long should I be on it . He said I usually do 2 weeks of casodex before Lupron shot so I say I have another 40 pills left he says take them .... is more better
Rmurchu
in
Advanced Prostate Cancer
5 years ago
Psa after six months while lupron and casodex
hello, what do you think? my father 69 years 2016 radical prostatectomy pt 3b gleason 8 psa post op 0.24 3 months later 0.56 2017 radiotherapy that failed psa a year later about 2 in september 2018: lupron, casodex December 2018 psa 0.08 April 2019 0.11
hello, what do you think? my father 69 years 2016 radical prostatectomy pt 3b gleason 8 psa post op 0.24 3 months later 0.56 2017 radiotherapy that failed psa a year later about 2 in september 2018: lupron, casodex December 2018 psa 0.08 April 2019 0.11
Katiafrench
in
Advanced Prostate Cancer
5 years ago
Rising psa
My 81 year old husband diagnosed 1/2016 with mets to many bones. Hormone therapy has worked well. Casodex 18 months now xtandi, eligard, and xgeva for over 18 months. His PSA went to <.01 almost immediately but now for the last 6 months has risen by .1 each month. It is now .7. The MO doesn’t seem
My 81 year old husband diagnosed 1/2016 with mets to many bones. Hormone therapy has worked well. Casodex 18 months now xtandi, eligard, and xgeva for over 18 months. His PSA went to <.01 almost immediately but now for the last 6 months has risen by .1 each month. It is now .7. The MO doesn’t seem
Bball
in
Advanced Prostate Cancer
5 years ago
Drug Resistence
Hey guys, My Father is currently on his third round of hormone blockade. However it appears he has become Zytiga and or Degarelix resistant. PSA Feb 25th was 22 and PSA March 25th is 24. He used Casodex on his first hormone blockade run in March 2014. He is Chemotherapy and Radiation naive. Our
Hey guys, My Father is currently on his third round of hormone blockade. However it appears he has become Zytiga and or Degarelix resistant. PSA Feb 25th was 22 and PSA March 25th is 24. He used Casodex on his first hormone blockade run in March 2014. He is Chemotherapy and Radiation naive. Our
taylor123
in
Advanced Prostate Cancer
5 years ago
LU 177 now or later?
I had a prostectomy by robotic surgery 7 years ago. It was Gleason 9 and had a little outside the capsule, but my surgeon thought he got it all, so sent me home to have PSA'a 4 x per year. The highest my PSA had been was 8.8 before surgery. In 2018, my PSA started to climb to about 0.6, so I was sent
I had a prostectomy by robotic surgery 7 years ago. It was Gleason 9 and had a little outside the capsule, but my surgeon thought he got it all, so sent me home to have PSA'a 4 x per year. The highest my PSA had been was 8.8 before surgery. In 2018, my PSA started to climb to about 0.6, so I was sent
kiskadog
in
Advanced Prostate Cancer
5 years ago
Casodex and liver problem?
My father is suffering from cancer he is on casodex one a day He vomit blood and black stool due to esophageal varices (condition due to liver problem) He was HCV possitive but PCR test reveals not detected . My question is that is casodex is destroying his liver ??
My father is suffering from cancer he is on casodex one a day He vomit blood and black stool due to esophageal varices (condition due to liver problem) He was HCV possitive but PCR test reveals not detected . My question is that is casodex is destroying his liver ??
Hidden
in
Advanced Prostate Cancer
5 years ago
Successful PSMA Lu177 treatment of hormone-sensitive PCa
tango65 reported that he had his lymph node mets treated with Lu177 in Munich. They were gone after one cycle of Lu177: https://healthunlocked.com/advanced-prostate-cancer/posts/138579678/lutetium-177-treatment-options?responses=138638930 So I thought I would also get my eight lymph node mets treated
tango65 reported that he had his lymph node mets treated with Lu177 in Munich. They were gone after one cycle of Lu177: https://healthunlocked.com/advanced-prostate-cancer/posts/138579678/lutetium-177-treatment-options?responses=138638930 So I thought I would also get my eight lymph node mets treated
GP24
in
Advanced Prostate Cancer
5 years ago
Just stared casodex now new doc says stop
Dx in Florida , Gleason 10 doc prescribed casodex to start until we can get back to Canada after the scan tomorrow. So he has taken 2 pills and our uro in Toronto says stop that immediately ....what’s going on ? No explanation as to why... any thoughts
Dx in Florida , Gleason 10 doc prescribed casodex to start until we can get back to Canada after the scan tomorrow. So he has taken 2 pills and our uro in Toronto says stop that immediately ....what’s going on ? No explanation as to why... any thoughts
Rmurchu
in
Advanced Prostate Cancer
5 years ago
Still need advice
Ok guys I’ve got about eight days to decide about dynamo trial at MDAnderson. I’m 61 had casodex rad surgery, radiation and lupron injections every 3 months. I’ve never had two drugs at once but individually not working. Overall I feel great and don’t have any issues except BP which is controlled well.they
Ok guys I’ve got about eight days to decide about dynamo trial at MDAnderson. I’m 61 had casodex rad surgery, radiation and lupron injections every 3 months. I’ve never had two drugs at once but individually not working. Overall I feel great and don’t have any issues except BP which is controlled well.they
spm58
in
Advanced Prostate Cancer
5 years ago
asking for members' input
Hi guys. My dad is currently being treated for metastatic prostate cancer and I wanted to get some input from the community. Dx'd 10/2018 at age 66, multiple bone mets. Initial PSA 2230. Gleason 4+3. No visceral mets. Started on Lupron and Casodex and added up front docetaxel. PSA has fallen to 0.06
Hi guys. My dad is currently being treated for metastatic prostate cancer and I wanted to get some input from the community. Dx'd 10/2018 at age 66, multiple bone mets. Initial PSA 2230. Gleason 4+3. No visceral mets. Started on Lupron and Casodex and added up front docetaxel. PSA has fallen to 0.06
mediocra
in
Advanced Prostate Cancer
5 years ago
lupron or casodex
my husband was given the choice of 6 months of lupron, or 2 years of casodex. along with radiation to prostate bed + nodes. (cleveland clinic) if you were offered this choice, which one did you choose & why? any regrets?
my husband was given the choice of 6 months of lupron, or 2 years of casodex. along with radiation to prostate bed + nodes. (cleveland clinic) if you were offered this choice, which one did you choose & why? any regrets?
pwallace
in
Advanced Prostate Cancer
5 years ago
Best ADT for CVD?
My husband is going to have ADT + Zytiga +radiation (prostate +lymph nodes pelvis + metastasis) in an aggressive approach to oligometastatic cancer (T3b, N1 M1, Gleason 9). He is fit but has atheroscleroses and will need stents. Now for ADT I thought Degarelix would be the best choice regarding CVD.
My husband is going to have ADT + Zytiga +radiation (prostate +lymph nodes pelvis + metastasis) in an aggressive approach to oligometastatic cancer (T3b, N1 M1, Gleason 9). He is fit but has atheroscleroses and will need stents. Now for ADT I thought Degarelix would be the best choice regarding CVD.
Hidden
in
Advanced Prostate Cancer
5 years ago
Cabazitaxel/Carboplatin w/4.4 PSA zenith
What about requesting it after 3.5 years on Lupron, 1 on Casodex and 2 months on Xtandi (rough time estimates) w/a nadir of .92/peak of 4.2 PSA? Am I overboard? Nous Defions Crabcrusher
What about requesting it after 3.5 years on Lupron, 1 on Casodex and 2 months on Xtandi (rough time estimates) w/a nadir of .92/peak of 4.2 PSA? Am I overboard? Nous Defions Crabcrusher
Crabcrushe
in
Advanced Prostate Cancer
5 years ago
Casodex after failing Xtandi and Lupron
G9 cancer, diagnosis 2005 with PSA 5.5 then. No treatment of any type,,no RP, RT, ADT for next 13 years. PSA by early(March) 2017 had climbed to 70, MRI and Pet CT were clean. September PSA had jumped to 260 MRI scan was normal showing contained tumor in Prostate. However Pet CT showed Mets
G9 cancer, diagnosis 2005 with PSA 5.5 then. No treatment of any type,,no RP, RT, ADT for next 13 years. PSA by early(March) 2017 had climbed to 70, MRI and Pet CT were clean. September PSA had jumped to 260 MRI scan was normal showing contained tumor in Prostate. However Pet CT showed Mets
Sxrxrnr1
in
Advanced Prostate Cancer
5 years ago
Please shoot holes in this plan.
Dx Stage 4 Gl 9 bone mets only, PSA 41, 6 cy. docataxel, leuprolide since 10/16, PSA 1.2, doubled in a year, added bicalutamide, doubled in a year, swapped out Casodex for enzalutamide, roughly half way through the Provenge thang. Plan to pause Lupron/Xtandi for 2 quarters, receive SBRT in Sep, cavitaxel
Dx Stage 4 Gl 9 bone mets only, PSA 41, 6 cy. docataxel, leuprolide since 10/16, PSA 1.2, doubled in a year, added bicalutamide, doubled in a year, swapped out Casodex for enzalutamide, roughly half way through the Provenge thang. Plan to pause Lupron/Xtandi for 2 quarters, receive SBRT in Sep, cavitaxel
Crabcrushe
in
Advanced Prostate Cancer
5 years ago
Need Advice to next level
Hello everyone, I need some advice. Diagnosed almost 2 years ago. Found my cancer had spread to lymph but not bone. I had radical prostatectomy, and was put on casodex. Psa climbed so did radiation. Still climbed up to 1.6 from .4. Put on lupron and had two 3- month injections so far and jumped to 4.6
Hello everyone, I need some advice. Diagnosed almost 2 years ago. Found my cancer had spread to lymph but not bone. I had radical prostatectomy, and was put on casodex. Psa climbed so did radiation. Still climbed up to 1.6 from .4. Put on lupron and had two 3- month injections so far and jumped to 4.6
spm58
in
Advanced Prostate Cancer
5 years ago
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