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FDA approves niraparib and abiraterone acetate plus prednisone for BRCA-mutated metastatic castration-resistant prostate cancer - 08/11/2023
On August 11, 2023, the Food and Drug Administration approved the fixed dose combination of niraparib and abiraterone acetate (Akeega, Janssen Biotech, Inc.), with prednisone, for adult patients with deleterious or suspected deleterious BRCA-mutated castration-resistant prostate cancer (mCRPC), as determined
On August 11, 2023, the Food and Drug Administration approved the fixed dose combination of niraparib and abiraterone acetate (Akeega, Janssen Biotech, Inc.), with prednisone, for adult patients with deleterious or suspected deleterious BRCA-mutated castration-resistant prostate cancer (mCRPC), as determined
cujoe
in
Fight Prostate Cancer
11 months ago
Treatment and Prevention Strategies for Cognitive Function in PCa
Treatment and Prevention strategies for cognitive function in men being treated for advanced prostate cancer. Mild cognitive impairment (“brain fog” chemo-brain”) is common and widely recognized in those being treated with ADT and androgen signaling drugs, as well as with taxane chemotherapy. I am highlighting
Treatment and Prevention strategies for cognitive function in men being treated for advanced prostate cancer. Mild cognitive impairment (“brain fog” chemo-brain”) is common and widely recognized in those being treated with ADT and androgen signaling drugs, as well as with taxane chemotherapy. I am highlighting
MateoBeach
in
Fight Prostate Cancer
6 months ago
Low Testosterone and value of continuing Hormone Therapy
83 year old male with a question: My understanding is that the role of hormone therapy is to lower one’s testosterone level. Does hormone therapy provide additional benefits in fighting prostate cancer beyond lowering testosterone levels? I was diagnosed with high grade prostate cancer (Gleason 10
83 year old male with a question: My understanding is that the role of hormone therapy is to lower one’s testosterone level. Does hormone therapy provide additional benefits in fighting prostate cancer beyond lowering testosterone levels? I was diagnosed with high grade prostate cancer (Gleason 10
saniku
in
Advanced Prostate Cancer
5 months ago
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My PSA tripled in 8 months
I had my RP in Jan 31, 2023, started hormonal therapy from April 17 with Diphereline every 28 days plus one Casodex daily. My PSA went down to 0.005 from May to November. Yesterday I had my blood test again and the report indicated my PSA has jumped to 0.159. I am panic. Can you explain what does
I had my RP in Jan 31, 2023, started hormonal therapy from April 17 with Diphereline every 28 days plus one Casodex daily. My PSA went down to 0.005 from May to November. Yesterday I had my blood test again and the report indicated my PSA has jumped to 0.159. I am panic. Can you explain what does
Formosan
in
Advanced Prostate Cancer
6 months ago
Can HRT stop working?
Hi, I had a total hysterectomy June 22 and have been on everol estrogen 100mg patches since and my menopause symptoms were controlled for the most. However, these past few weeks my symptoms have been creeping back starting with sleeplessness, night sweats, brain fog and now my skin is itchy as anything
Hi, I had a total hysterectomy June 22 and have been on everol estrogen 100mg patches since and my menopause symptoms were controlled for the most. However, these past few weeks my symptoms have been creeping back starting with sleeplessness, night sweats, brain fog and now my skin is itchy as anything
EvieJ70
in
Menopause and Perimenopause Support
6 months ago
Welcome to Stage Denial
Greetings, fellow warriors fighting prostate cancer. Mababa here, with a funny-sounding username that's a joining of my first name initial with the last part of the name of the city where I was born: Addis Ababa, seventy-one years and six months ago. Actually, I'm not quite in the fight yet, so I can't
Greetings, fellow warriors fighting prostate cancer. Mababa here, with a funny-sounding username that's a joining of my first name initial with the last part of the name of the city where I was born: Addis Ababa, seventy-one years and six months ago. Actually, I'm not quite in the fight yet, so I can't
mababa
in
Advanced Prostate Cancer
6 months ago
Wow ! Newly Diagnosed Prostate Cancer. Greatly appreciate some Guidance with all this new Technology. Tampa Bay Area.
72yo – Gleason 7 – (4+3)- Group 3 - PSA 6.456 – PHI 91.7 – Free 12.86% - Localized in Left Lobe – Clean PSMA- 8mm Lesion – 15 cores taken – 5 unfavorable – 36cc PH - Hi All, Recently diagnosed with PC. Had the MRI, Biopsy and Pet PSMA done. Urologist suggested ERT + HT ( 6 mths). Started to research
72yo – Gleason 7 – (4+3)- Group 3 - PSA 6.456 – PHI 91.7 – Free 12.86% - Localized in Left Lobe – Clean PSMA- 8mm Lesion – 15 cores taken – 5 unfavorable – 36cc PH - Hi All, Recently diagnosed with PC. Had the MRI, Biopsy and Pet PSMA done. Urologist suggested ERT + HT ( 6 mths). Started to research
mijona
in
Prostate Cancer Network
5 months ago
prostrap injections
Hi All, thank you for the add- I am new here. I have ademomyosis, fibroids and also possibly endometriosis. I am listed for a total hysterectomy but start (thursday!) prostrap injections to see how I would cope with no ovaries (with add back HRT) and to check the effect on my terrible ovulation symptoms
Hi All, thank you for the add- I am new here. I have ademomyosis, fibroids and also possibly endometriosis. I am listed for a total hysterectomy but start (thursday!) prostrap injections to see how I would cope with no ovaries (with add back HRT) and to check the effect on my terrible ovulation symptoms
ForestFi
in
Endometriosis UK
6 months ago
Menopause Hot Flush Medication Gets Approval
Another article from the Guardian regarding an alternative to HRT for those suffering from hot flushes during menopause. However it looks like its only going to be available privately for now. https://www.theguardian.com/society/2023/dec/18/veoza-fezolinetant-menopause-drug-hot-flushes-wins-uk-approval
Another article from the Guardian regarding an alternative to HRT for those suffering from hot flushes during menopause. However it looks like its only going to be available privately for now. https://www.theguardian.com/society/2023/dec/18/veoza-fezolinetant-menopause-drug-hot-flushes-wins-uk-approval
Sparklingsunshine
in
Thyroid UK
6 months ago
PSA rise soon after surgery!
Writing regarding my dad. Worried and dont get any answers / just wait and see approach from medical team :( Dad 63 years old now, was diagnosed with prostate cancer october 2022. 2 small tumors 5x3 mm was shown on MR, no spread shown there. Biopsy showed gleason 3+4 ( 4 was 50%) Ralp surgery robotic
Writing regarding my dad. Worried and dont get any answers / just wait and see approach from medical team :( Dad 63 years old now, was diagnosed with prostate cancer october 2022. 2 small tumors 5x3 mm was shown on MR, no spread shown there. Biopsy showed gleason 3+4 ( 4 was 50%) Ralp surgery robotic
Daddysgirl83
in
Advanced Prostate Cancer
11 months ago
Psa rise soon after surgery, help!
Writing regarding my dad. Worried and dont get any answers / just wait and see approach from medical team :( Dad 63 years old now, was diagnosed with prostate cancer october 2022. 2 small tumors 5x3 mm was shown on MR, no spread shown there. Biopsy showed gleason 3+4 ( 4 was 40%). Ralp surgery robotic
Writing regarding my dad. Worried and dont get any answers / just wait and see approach from medical team :( Dad 63 years old now, was diagnosed with prostate cancer october 2022. 2 small tumors 5x3 mm was shown on MR, no spread shown there. Biopsy showed gleason 3+4 ( 4 was 40%). Ralp surgery robotic
Daddysgirl83
in
Fight Prostate Cancer
11 months ago
Cyproterone and Blood Pressure
I am currently on LHRH hormone therapy in preparation for radiotherapy followed by HDR brachytherapy for my locally advanced PCa, T3a Gleason 8, no visible mets fortunately. I have been suffering from quite unpleasant hot flushes which have shown no signs of going away. I discussed this with my consultant
I am currently on LHRH hormone therapy in preparation for radiotherapy followed by HDR brachytherapy for my locally advanced PCa, T3a Gleason 8, no visible mets fortunately. I have been suffering from quite unpleasant hot flushes which have shown no signs of going away. I discussed this with my consultant
tunybgur
in
Advanced Prostate Cancer
6 months ago
my life is miserable life due to hormone treatment (eligard) want to quit asap . questions to ask ? /experiences ?
Im a very active 61 - had zero symptoms - no peeing in the night etc and 15 PSA was only flagged while doing pre op for a hip replacement in January. Next PSA was 17 in March so in for biopsy - 8 positive biopsy samples of 48 taken but only one of concern with Gleason of 8. PET scan indicated borderline
Im a very active 61 - had zero symptoms - no peeing in the night etc and 15 PSA was only flagged while doing pre op for a hip replacement in January. Next PSA was 17 in March so in for biopsy - 8 positive biopsy samples of 48 taken but only one of concern with Gleason of 8. PET scan indicated borderline
moon1878
in
Prostate Cancer Network
6 months ago
Do your mental struggles show something wonderful about you?
As many know, I am a big advocate of Dr David Burns' work. He wrote "Feeling Great" and does the "Feeling Good" podcast. He developed TEAM CBT which is Testing, Empathy, Agenda-setting, Methods Cognitive Behavioral Therapy. He uses a hypothetical situation and asks if there was a magic button that cured
As many know, I am a big advocate of Dr David Burns' work. He wrote "Feeling Great" and does the "Feeling Good" podcast. He developed TEAM CBT which is Testing, Empathy, Agenda-setting, Methods Cognitive Behavioral Therapy. He uses a hypothetical situation and asks if there was a magic button that cured
LoveforAll41
in
Anxiety and Depression Support
6 months ago
Clinical trial: keep an eye on this
First results should be available by the first months of 2024. Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation Enhancing Medication (M3814) Versus Radium-223 Dichloride Plus M3814 Plus Avelumab (a Type of Immunotherapy) for Advanced Prostate Cancer Not Responsive
First results should be available by the first months of 2024. Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation Enhancing Medication (M3814) Versus Radium-223 Dichloride Plus M3814 Plus Avelumab (a Type of Immunotherapy) for Advanced Prostate Cancer Not Responsive
Maxone73
in
Advanced Prostate Cancer
6 months ago
Is it safe to use red light / near infrared therapy if you have Graves' disease?
Hi all, First a little bit of background about me. I am 49, living in Ireland. I have Graves's disease diagnosed by an endocrinologist who did antibody test etc.. After diagnosis I underwent 18 months on Carbimazole and then came off for a couple of months but my T3 and T4 shot back up again (and TSH
Hi all, First a little bit of background about me. I am 49, living in Ireland. I have Graves's disease diagnosed by an endocrinologist who did antibody test etc.. After diagnosis I underwent 18 months on Carbimazole and then came off for a couple of months but my T3 and T4 shot back up again (and TSH
MyNameIsAugust
in
Thyroid UK
11 months ago
Advice on natural hormone replacement while taking Warfarin.
Hello, I take Warfarin for the rest of my life after a PE. Currently 52 and in Menopause. I can never take an actual hormone replacement because of the ( pulmonary embolisms) I have takin Provitalize for 9 months now, it only helped with a few symptoms for a short amount of time. needing something
Hello, I take Warfarin for the rest of my life after a PE. Currently 52 and in Menopause. I can never take an actual hormone replacement because of the ( pulmonary embolisms) I have takin Provitalize for 9 months now, it only helped with a few symptoms for a short amount of time. needing something
Smokedalmonds
in
Anticoagulation Support
6 months ago
Chemo Vs ADT
So this is possibly the dumbest question I have asked. But the knowledge on this forum is worth tapping into even for people like me who struggle with all the complexities of PC. So, - ADT suppresses PC but will not kill it. Chemo on the other hand finds the PC cells and kills them. So why do
So this is possibly the dumbest question I have asked. But the knowledge on this forum is worth tapping into even for people like me who struggle with all the complexities of PC. So, - ADT suppresses PC but will not kill it. Chemo on the other hand finds the PC cells and kills them. So why do
Mike58
in
Advanced Prostate Cancer
6 months ago
Declining psa #8
Gm folks, hope all is well during this Christmas season… I’ve just received my 8th psa test after getting off ADT, 9 months of using alternative meds ivermectin, cbd oil turmeric zinc ashwaganda n dim a natural estrogen blocker solely. Psa came in at .95 down from 1.29, 6 weeks ago and down from 1.95
Gm folks, hope all is well during this Christmas season… I’ve just received my 8th psa test after getting off ADT, 9 months of using alternative meds ivermectin, cbd oil turmeric zinc ashwaganda n dim a natural estrogen blocker solely. Psa came in at .95 down from 1.29, 6 weeks ago and down from 1.95
Nfler
in
Advanced Prostate Cancer
6 months ago
SE from ADT and two natural remedies I always use. Anger=kava kava, insomnia=wild lettuce.
Hi fellow warriors, i am sharing this because after being an herbalist and wild medicine harvester there are two absolutely essential herbs i use to counter ADT side effects. Be advised I make my own so cost does not factor into how much or how often i take it. The most important is wild lettuce (
Hi fellow warriors, i am sharing this because after being an herbalist and wild medicine harvester there are two absolutely essential herbs i use to counter ADT side effects. Be advised I make my own so cost does not factor into how much or how often i take it. The most important is wild lettuce (
KocoPr
in
Fight Prostate Cancer
6 months ago
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