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Cabazitaxel in combo with Carboplatin
Has anyone had this combination of chemo at the same time? If so did you have good results?
Has anyone had this combination of chemo at the same time? If so did you have good results?
Jeff3181
in
Advanced Prostate Cancer
2 years ago
Is it possible to have chemo again after radiation?
After 4yrs and several treatment protocols (zytiga, docetaxel, xtandi, lu177,
cabazitaxel
,
cabazitaxel
+carbo) my husband now has numerous mets on the spine and his pca has traveled to the rectum as well. Nothing worked. PSA kept rising altho his pca emits little PSA.
After 4yrs and several treatment protocols (zytiga, docetaxel, xtandi, lu177,
cabazitaxel
,
cabazitaxel
+carbo) my husband now has numerous mets on the spine and his pca has traveled to the rectum as well. Nothing worked. PSA kept rising altho his pca emits little PSA.
dvcarola2
in
Advanced Prostate Cancer
2 years ago
A lil levity for HU and an update after Cabazitaxel #11. In 2001 my daughter and I were in "Friends" episode"The one with Monica's Boots"
#11
Cabazitaxel
last Friday, but PSA climbed to 3.6 from 2.8 three weeks earlier :-(. T at 13.
#11
Cabazitaxel
last Friday, but PSA climbed to 3.6 from 2.8 three weeks earlier :-(. T at 13.
dockam
in
Advanced Prostate Cancer
2 years ago
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65th bday last Sunday (Dx'd in 2015) Did 65 miles over two months with Bonnie and did a bday 5k. #10 Cabazitaxel right now, just got Lupron
Have a phone appt with MO to see next step, looks like 9
Cabazitaxel
sessions didn't do it. Taxotere failed in 2021, so did Abiraterone and then Xtandi in 2020. May be time for a PSMA scan, since I'm on Kaiser Medicare now, then biopsy if large enough.
Have a phone appt with MO to see next step, looks like 9
Cabazitaxel
sessions didn't do it. Taxotere failed in 2021, so did Abiraterone and then Xtandi in 2020. May be time for a PSMA scan, since I'm on Kaiser Medicare now, then biopsy if large enough.
dockam
in
Advanced Prostate Cancer
2 years ago
'Substandard' Control Arms in Clinical Trials– Practice found common in prostate cancer studies
Thirty-five percent of patients had not received prior docetaxel, and 45% of docetaxel-pretreated patients had not received prior
cabazitaxel
-- treatments proven to improve survival in the mCRPC setting.
Thirty-five percent of patients had not received prior docetaxel, and 45% of docetaxel-pretreated patients had not received prior
cabazitaxel
-- treatments proven to improve survival in the mCRPC setting.
GeorgeGlass
in
Advanced Prostate Cancer
2 years ago
Update w/ Questions: Tumor growth w/o PSA rise; Chemo Round 2, Cabazitaxel This Time
I start 12 cycles of
Cabazitaxel
tomorrow. My MO expects me to handle it well, I hope she is right. Last time was kind of awful. Can y'all share your experience with
Cabazitaxel
, particularly if you have gotten another kind of chemo? Thank you everyone, and take care o' yourselves.
I start 12 cycles of
Cabazitaxel
tomorrow. My MO expects me to handle it well, I hope she is right. Last time was kind of awful. Can y'all share your experience with
Cabazitaxel
, particularly if you have gotten another kind of chemo? Thank you everyone, and take care o' yourselves.
BillNIttles
in
Advanced Prostate Cancer
2 years ago
Life expectancy shock revelation
This would be after finishing Docetaxel then having 2nd line
Cabazitaxel
which would work for 14 - 16 months. I am completely shocked and I'm obviously looking to retire now. With me being so far down the treatment path it's so less likely his prediction will be wrong isn't it?
This would be after finishing Docetaxel then having 2nd line
Cabazitaxel
which would work for 14 - 16 months. I am completely shocked and I'm obviously looking to retire now. With me being so far down the treatment path it's so less likely his prediction will be wrong isn't it?
konichiwa12
in
Advanced Prostate Cancer
2 years ago
Incontinence but why?
After 3rd Chemo(
Cabazitaxel
) reduced dose was suffering constipation for 2 days before then all went crazy!
After 3rd Chemo(
Cabazitaxel
) reduced dose was suffering constipation for 2 days before then all went crazy!
Yorkielover2
in
Advanced Prostate Cancer
2 years ago
Lu-177 or Cabazitaxel
- From your knowledge, my dad should take Lu177 or
Cabazitaxel
next? My dad experiences ATD, Docetaxel and Zytiga. - Please share if you have any other thought Thanks you in advance for your sharing,
- From your knowledge, my dad should take Lu177 or
Cabazitaxel
next? My dad experiences ATD, Docetaxel and Zytiga. - Please share if you have any other thought Thanks you in advance for your sharing,
Hidden
in
Advanced Prostate Cancer
2 years ago
The combination of cabazitaxel and cyproheptadine is a promising candidate for overcoming prostate cancer
Prediction of Synergistic Drug Combinations for Prostate Cancer by Transcriptomic and Network Characteristics Prostate cancer (PRAD) is a major cause of cancer-related deaths. Current monotherapies show limited efficacy due to often rapidly emerging resistance. Combination therapies could provide an
Prediction of Synergistic Drug Combinations for Prostate Cancer by Transcriptomic and Network Characteristics Prostate cancer (PRAD) is a major cause of cancer-related deaths. Current monotherapies show limited efficacy due to often rapidly emerging resistance. Combination therapies could provide an
Hidden
in
Advanced Prostate Cancer
2 years ago
Pleura Effusion drained twice now since June 20th
Fast forward to now 1 liter drained June 20th then July 25 3 liters from the right side(always there) He has had 6 Taxotere treatments then 3 month break but we were told have to do something something while waiting for Pluvicto(PSA 1100) Has had 2 reduced Chemo treatments (
Cabazitaxel
) His oxygen level
Fast forward to now 1 liter drained June 20th then July 25 3 liters from the right side(always there) He has had 6 Taxotere treatments then 3 month break but we were told have to do something something while waiting for Pluvicto(PSA 1100) Has had 2 reduced Chemo treatments (
Cabazitaxel
) His oxygen level
Yorkielover2
in
Advanced Prostate Cancer
2 years ago
Bone marrow suppression with cabazitaxel carboplatin combination
I see a number of members are receiving combination treatment of
cabazitaxel
and carboplatin. I'm wondering how that affects bone marrow suppression. Please comment on your experience with red and white blood counts while receiving the treatment
I see a number of members are receiving combination treatment of
cabazitaxel
and carboplatin. I'm wondering how that affects bone marrow suppression. Please comment on your experience with red and white blood counts while receiving the treatment
Javelin18
in
Advanced Prostate Cancer
2 years ago
My Jevtana/Carboplatin results to date. Plus participation in Bipolar Androgen Therapy testing
I asked about adding carboplatin to the current chemotherapy (
cabazitaxel
) and she agreed to add it. She didn’t seem positive but more accommodating to my suggestion.
I asked about adding carboplatin to the current chemotherapy (
cabazitaxel
) and she agreed to add it. She didn’t seem positive but more accommodating to my suggestion.
Mount_Rainier
in
Advanced Prostate Cancer
2 years ago
4th Taxotere treatment past Monday! Labs show bump again in PSA!
Has anyone switched to
Cabazitaxel
at this point? Oncologist thinking about it .Husband having very hard time with chemo! First week mostly sleeping .Eats small meals. Mentioned to Pallative care Doctor feels like right leg will go out from under him. Using cane now.
Has anyone switched to
Cabazitaxel
at this point? Oncologist thinking about it .Husband having very hard time with chemo! First week mostly sleeping .Eats small meals. Mentioned to Pallative care Doctor feels like right leg will go out from under him. Using cane now.
Yorkielover2
in
Advanced Prostate Cancer
2 years ago
Thanks, this is why I'm here
I was able to keep my hemoglobin steady following my
cabazitaxel
infusion , and avoid getting the transfusion. Back in the early 2000's I consulted at Microsoft editing the DotNet users guide. It was a collection of articles on how to transition from individual PC computing to cloud computing.
I was able to keep my hemoglobin steady following my
cabazitaxel
infusion , and avoid getting the transfusion. Back in the early 2000's I consulted at Microsoft editing the DotNet users guide. It was a collection of articles on how to transition from individual PC computing to cloud computing.
Javelin18
in
Advanced Prostate Cancer
2 years ago
Treatment update... Back on the chemo
Plan B:
Cabazitaxel
with Carboplatin... And Neulasta... Age 59... Stage 4 Gleason 9 BRCA2 positive. Changed from CS to CR... resistant instead of sensitive somewhere in the last six months. Lynparza (Oliperab) was working great for 4 months, until Nov 2021.
Plan B:
Cabazitaxel
with Carboplatin... And Neulasta... Age 59... Stage 4 Gleason 9 BRCA2 positive. Changed from CS to CR... resistant instead of sensitive somewhere in the last six months. Lynparza (Oliperab) was working great for 4 months, until Nov 2021.
subliminaldood
in
Advanced Prostate Cancer
2 years ago
Rock on Cabazitaxel!!
about the chances of the next treatment -
cabazitaxel
, commenced 3 weeks ago , doing much. But about a week ago the terrible pain he’d been suffering in his coccyx suddenly started improving and he can sit comfortably again.
about the chances of the next treatment -
cabazitaxel
, commenced 3 weeks ago , doing much. But about a week ago the terrible pain he’d been suffering in his coccyx suddenly started improving and he can sit comfortably again.
Crummy64
in
Advanced Prostate Cancer
2 years ago
In whom does BAT work? Some new clues
They also pointed out that in the recent trial of
cabazitaxel
+carboplatin at MD Anderson, the same genomic predictors of success were found.
They also pointed out that in the recent trial of
cabazitaxel
+carboplatin at MD Anderson, the same genomic predictors of success were found.
Tall_Allen
in
Advanced Prostate Cancer
2 years ago
Choosing a trial
I'm now starting
cabazitaxel
to hold the cancer at bay while I wait to join a trial. I spoke with City of Hope about joining their CAR -T trial, for which it looks like I would be a good candidate.
I'm now starting
cabazitaxel
to hold the cancer at bay while I wait to join a trial. I spoke with City of Hope about joining their CAR -T trial, for which it looks like I would be a good candidate.
Javelin18
in
Advanced Prostate Cancer
2 years ago
Confusion As To Next Treatments - Carboplatin and Cabazitaxel
I asked about adding carboplatin to the current chemotherapy (
cabazitaxel
) and she agreed to add it. She didn’t seem positive but more accommodating to my suggestion.
I asked about adding carboplatin to the current chemotherapy (
cabazitaxel
) and she agreed to add it. She didn’t seem positive but more accommodating to my suggestion.
Mount_Rainier
in
Advanced Prostate Cancer
2 years ago
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